Abstract: In a described example, a sheath has an elongate tubular sidewall that includes a deflectable distal body end portion that extends from a proximal body end portion. The distal body end portion includes a deflection control portion extending axially along part of the tubular sidewall of the distal body end portion, such as defining a cylindrical sector of the tubular sidewall. The deflection control portion has a different stiffness relative to at least a diametrically opposed axially extending sector of the tubular sidewall of the distal body end portion to provide a deflection zone of the distal body end portion multiple different bend diameters.

Abstract: Systems and methods for serial analysis of electrocardiograms are presented, wherein serial electrocardiographic (ECG) assessment is incorporated with three-dimensional vectorial analysis of the cardiac electrical signal, using changes in novel 3D-based vectorial markers over time to improve diagnostic sensitivity for acute coronary syndromes (ACS), and improve differentiation of ACS from the broad range of heart diseases that resemble ACS on ECG.

Abstract: Apparatus for control of physiological functions, including physiological functions of the urinary tract, using at least one electrode sized and configured to be located on, in, or near a targeted component of the pudendal nerve, and/or its branch(es), and/or its spinal root(s). The apparatus includes a controller coupled to the electrode to apply an electrical signal having an amplitude to the electrode at a selected frequency to stimulate the targeted component. The controller operates in a first mode to apply a first frequency or range of frequencies without substantially changing the amplitude for achieving a first physiologic response (e.g., controlling urinary continence) and the controller operates in a second mode to apply a second frequency or range of frequencies, different than the first frequency, for achieving a second physiologic response different than the first physiologic response (e.g., controlling micturition).

Abstract: Systems and methods control physiological functions of the urinary tract using at least one electrode sized and configured to be located on, in, or near a targeted component of the pudendal nerve. The systems and methods apply an electrical signal to the electrode at a selected frequency to stimulate the targeted component. The selected frequency is a first frequency or range of frequencies for achieving a first physiologic response (e.g., controlling urinary continence) and a second frequency or range of frequencies, different than the first frequency, for achieving a second physiologic response different than the first physiologic response (e.g., controlling micturition).