Patents by Inventor Brian Wodlinger
Brian Wodlinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11051790Abstract: This invention provides a system and method for providing Indicator Features in high resolution micro-ultrasound prostate images, wherein the ultrasound device operates at a center frequency of 15 MHz and above. Indicator Features are features, which have been identified alone and/or in combination with other features in high resolution micro-ultrasound images, and have been determined to be significantly statistically correlated to either benign tissue or some grade of cancerous tissue on the basis of predictive probabilities. These Indicator Features can be used to train a linear or non-linear classifier, which can be used to classify patient images of the prostate. These Indicator Features can be used to guide a clinician as to where to take a biopsy core from the prostate, as well as assist in diagnosis of the tissue.Type: GrantFiled: November 10, 2016Date of Patent: July 6, 2021Assignee: Exact Imaging, Inc.Inventors: Brian Wodlinger, Theresa McGrath, Jerrold Wen
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Patent number: 10994131Abstract: Methods of treating pain are disclosed, wherein a non-pulsed, low-frequency electrical current is applied to the nerve carrying the pain signals in order to suppress transmission of those signals. In desired embodiments, the current is applied in a direction transverse to the nerve axis. Such currents have been found not to induce motor-neuron recruitment, meaning these methods can treat pain without causing muscle spasm or other muscular responses. A cuff for applying such a current transverse to the nerve axis is also disclosed.Type: GrantFiled: February 26, 2018Date of Patent: May 4, 2021Assignee: CASE WESTERN RESERVE UNIVERSITYInventors: Dominique M. Durand, Brian Wodlinger
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Patent number: 10779730Abstract: A method and an electrode for monitoring electrical activity in a nerve are provided along with a method of fabricating such an electrode. The electrode includes a cuff formed from a chronically-implantable material that, when implanted, extends at least partially around an external periphery of the nerve. A plurality of contacts are supported by the cuff to be arranged adjacent to different regions of the nerve distributed along a transverse direction of the nerve when the cuff is implanted. A multiplexer is coupled to the cuff to be implanted for receiving electrical signals introduced to the contacts by the nerve and multiplexing, in vivo, the electrical signals to be transmitted to an external receiver over a shared communication channel.Type: GrantFiled: January 10, 2018Date of Patent: September 22, 2020Assignee: CASE WESTERN RESERVE UNIVERSITYInventors: Dominique M. Durand, Brian Wodlinger
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Patent number: 10470680Abstract: Systems and methods are provided for controlling an entity in response to activity in a peripheral nerve comprising a plurality of fascicles. A multicontact electrode assembly is configured to record activity from the peripheral nerve. A processing component includes a sensor mapping component configured to quantify activity associated with a proper subset of the plurality of fascicles, an evaluation component configured to determine an adjustment of the status of the controlled entity from the quantified activity of the proper subset of the plurality of fascicles, and a controller configured to provide a control signal, representing the adjustment of the status of the controlled entity, to the controlled entity.Type: GrantFiled: March 15, 2017Date of Patent: November 12, 2019Assignee: CASE WESTERN RESERVE UNIVERSITYInventors: Dominique M. Durand, Brian Wodlinger
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Publication number: 20180333140Abstract: This invention provides a system and method for providing Indicator Features in high resolution micro-ultrasound prostate images, wherein the ultrasound device operates at a center frequency of 15 MHz and above. Indicator Features are features, which have been identified alone and/or in combination with other features in high resolution micro-ultrasound images, and have been determined to be significantly statistically correlated to either benign tissue or some grade of cancerous tissue on the basis of predictive probabilities. These Indicator Features can be used to train a linear or non-linear classifier, which can be used to classify patient images of the prostate. These Indicator Features can be used to guide a clinician as to where to take a biopsy core from the prostate, as well as assist in diagnosis of the tissue.Type: ApplicationFiled: November 10, 2016Publication date: November 22, 2018Inventors: Brian WODLINGER, Theresa MCGRATH, Jerrold WEN
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Publication number: 20180200507Abstract: Methods of treating pain are disclosed, wherein a non-pulsed, low-frequency electrical current is applied to the nerve carrying the pain signals in order to suppress transmission of those signals. In desired embodiments, the current is applied in a direction transverse to the nerve axis. Such currents have been found not to induce motor-neuron recruitment, meaning these methods can treat pain without causing muscle spasm or other muscular responses. A cuff for applying such a current transverse to the nerve axis is also disclosed.Type: ApplicationFiled: February 26, 2018Publication date: July 19, 2018Inventors: Dominique M. Durand, Brian Wodlinger
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Publication number: 20180146853Abstract: A method and an electrode for monitoring electrical activity in a nerve are provided along with a method of fabricating such an electrode. The electrode includes a cuff formed from a chronically-implantable material that, when implanted, extends at least partially around an external periphery of the nerve. A plurality of contacts are supported by the cuff to be arranged adjacent to different regions of the nerve distributed along a transverse direction of the nerve when the cuff is implanted. A multiplexer is coupled to the cuff to be implanted for receiving electrical signals introduced to the contacts by the nerve and multiplexing, in vivo, the electrical signals to be transmitted to an external receiver over a shared communication channel.Type: ApplicationFiled: January 10, 2018Publication date: May 31, 2018Inventors: Dominique M. Durand, Brian Wodlinger
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Patent number: 9980645Abstract: A method and an electrode for monitoring electrical activity in a nerve are provided along with a method of fabricating such an electrode. The electrode includes a cuff formed from a chronically-implantable material that, when implanted, extends at least partially around an external periphery of the nerve. A plurality of contacts are supported by the cuff to be arranged adjacent to different regions of the nerve distributed along a transverse direction of the nerve when the cuff is implanted. A multiplexer is coupled to the cuff to be implanted for receiving electrical signals introduced to the contacts by the nerve and multiplexing, in vivo, the electrical signals to be transmitted to an external receiver over a shared communication channel.Type: GrantFiled: June 21, 2012Date of Patent: May 29, 2018Assignee: Case Western Reserve UniversityInventors: Dominique M. Durand, Brian Wodlinger
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Patent number: 9974947Abstract: Methods of treating pain are disclosed, wherein a non-pulsed, low-frequency electrical current is applied to the nerve carrying the pain signals in order to suppress transmission of those signals. In desired embodiments, the current is applied in a direction transverse to the nerve axis. Such currents have been found not to induce motor-neuron recruitment, meaning these methods can treat pain without causing muscle spasm or other muscular responses. A cuff for applying such a current transverse to the nerve axis is also disclosed.Type: GrantFiled: April 13, 2015Date of Patent: May 22, 2018Assignee: Case Western Reserve UniversityInventors: Dominique M. Durand, Brian Wodlinger
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Publication number: 20170181652Abstract: Systems and methods are provided for controlling an entity in response to activity in a peripheral nerve comprising a plurality of fascicles. A multicontact electrode assembly is configured to record activity from the peripheral nerve. A processing component includes a sensor mapping component configured to quantify activity associated with a proper subset of the plurality of fascicles, an evaluation component configured to determine an adjustment of the status of the controlled entity from the quantified activity of the proper subset of the plurality of fascicles, and a controller configured to provide a control signal, representing the adjustment of the status of the controlled entity, to the controlled entity.Type: ApplicationFiled: March 15, 2017Publication date: June 29, 2017Inventors: Dominique M. Durand, Brian Wodlinger
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Patent number: 9636239Abstract: Systems and methods are provided for controlling an entity in response to activity in a peripheral nerve comprising a plurality of fascicles. A multicontact electrode assembly is configured to record activity from the peripheral nerve. A processing component includes a sensor mapping component configured to quantify activity associated with a proper subset of the plurality of fascicles, an evaluation component configured to determine an adjustment of the status of the controlled entity from the quantified activity of the proper subset of the plurality of fascicles, and a controller configured to provide a control signal, representing the adjustment of the status of the controlled entity, to the controlled entity.Type: GrantFiled: August 20, 2010Date of Patent: May 2, 2017Assignee: Case Western Reserve UniversityInventors: Dominique M. Durand, Brian Wodlinger
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Publication number: 20150224301Abstract: Methods of treating pain are disclosed, wherein a non-pulsed, low-frequency electrical current is applied to the nerve carrying the pain signals in order to suppress transmission of those signals. In desired embodiments, the current is applied in a direction transverse to the nerve axis. Such currents have been found not to induce motor-neuron recruitment, meaning these methods can treat pain without causing muscle spasm or other muscular responses. A cuff for applying such a current transverse to the nerve axis is also disclosed.Type: ApplicationFiled: April 13, 2015Publication date: August 13, 2015Inventors: Dominique M. Durand, Brian Wodlinger
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Patent number: 9037248Abstract: Methods of treating pain are disclosed, wherein a non-pulsed, low-frequency electrical current is applied to the nerve carrying the pain signals in order to suppress transmission of those signals. In desired embodiments, the current is applied in a direction transverse to the nerve axis. Such currents have been found not to induce motor-neuron recruitment, meaning these methods can treat pain without causing muscle spasm or other muscular responses. A cuff for applying such a current transverse to the nerve axis is also disclosed.Type: GrantFiled: August 10, 2011Date of Patent: May 19, 2015Assignee: Case Western Reserve UniversityInventors: Dominique M. Durand, Brian Wodlinger
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Publication number: 20130138193Abstract: Methods of treating pain are disclosed, wherein a non-pulsed, low-frequency electrical current is applied to the nerve carrying the pain signals in order to suppress transmission of those signals. In desired embodiments, the current is applied in a direction transverse to the nerve axis. Such currents have been found not to induce motor-neuron recruitment, meaning these methods can treat pain without causing muscle spasm or other muscular responses. A cuff for applying such a current transverse to the nerve axis is also disclosed.Type: ApplicationFiled: August 10, 2011Publication date: May 30, 2013Applicant: CASE WESTERN RESERVE UNIVERSITYInventors: Dominique M. Durand, Brian Wodlinger
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Publication number: 20110046506Abstract: Systems and methods are provided for controlling an entity in response to activity in a peripheral nerve comprising a plurality of fascicles. A multicontact electrode assembly is configured to record activity from the peripheral nerve. A processing component includes a sensor mapping component configured to quantify activity associated with a proper subset of the plurality of fascicles, an evaluation component configured to determine an adjustment of the status of the controlled entity from the quantified activity of the proper subset of the plurality of fascicles, and a controller configured to provide a control signal, representing the adjustment of the status of the controlled entity, to the controlled entity.Type: ApplicationFiled: August 20, 2010Publication date: February 24, 2011Inventors: DOMINIQUE M. DURAND, Brian Wodlinger