Patents by Inventor Bridget Cole

Bridget Cole has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF MICROBIALLY INDUCED AMYLOID
    Publication number: 20230113225
    Abstract: The present disclosure provides compounds useful for the prevention of amyloid formation and the treatment of amyloid related disorders, including synucleopathics such as Parkinson's Disease.
    Type: Application
    Filed: August 4, 2022
    Publication date: April 13, 2023
    Applicant: Axial Therapeutics, Inc.
    Inventors: Anthony Stewart Campbell, Bridget Cole, Alessandra Bartolozzi
  • INHIBITORS OF MICROBIALLY INDUCED AMYLOID
    Publication number: 20230103887
    Abstract: The present disclosure provides compounds useful for the prevention of amyloid formation and the treatment of amyloid related disorders, including synucleopathies such as Parkinson's Disease.
    Type: Application
    Filed: August 4, 2022
    Publication date: April 6, 2023
    Applicant: Axial Therapeutics, Inc.
    Inventors: Anthony Stewart Campbell, Bridget Cole, Alessandra Bartolozzi
  • COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20220402925
    Abstract: The invention relates to a compound of Formula I, pharmaceutical compositions comprising a compound of Formula I, and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I to a subject in need thereof.
    Type: Application
    Filed: June 2, 2022
    Publication date: December 22, 2022
    Inventors: Feng Li, Christopher Oalmann, Bridget Cole, Andrew Kolodziej, Richard Fitzpatrick
  • Inhibitors of microbially induced amyloid
    Patent number: 11505528
    Abstract: The present disclosure provides compounds useful for the prevention of amyloid formation and the treatment of amyloid related disorders, including synucleopathies such as Parkinson's Disease.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: November 22, 2022
    Assignee: Axial Therapeutics, Inc.
    Inventors: Anthony Stewart Campbell, Bridget Cole, Alessandra Bartolozzi
  • INHIBITORS OF MICROBIALLY INDUCED AMYLOID
    Publication number: 20200290970
    Abstract: The present disclosure provides compounds useful for the prevention of amyloid formation and the treatment of amyloid related disorders, including synucleopathies such as Parkinson's Disease.
    Type: Application
    Filed: August 6, 2018
    Publication date: September 17, 2020
    Applicant: Axial Biotherapeutics, Inc.
    Inventors: Anthony Stewart Campbell, Bridget Cole, Alessandra Bartolozzi
  • RHO KINASE INHIBITORS
    Publication number: 20120202793
    Abstract: The present invention relates to inhibitors of ROCK1 and ROCK2, which may be selective for ROCK2, and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCK1 and/or ROCK2. Also provided are treatments combining inhibitors of ROCK1 and/or ROCK2 with statins.
    Type: Application
    Filed: March 9, 2010
    Publication date: August 9, 2012
    Inventors: Paul Sweetnam, Alessandra Bartolozzi, Anthony Stewart Campbell, Bridget Cole, Hope Foudoulakis, Brian Kirk, Hemalatha Seshadri, Siya Ram
  • Somatostatin antagonists and agonists that act at the sst subtype 2 receptor
    Publication number: 20050054581
    Abstract: Compounds according formula (I) A-G-Z-W and pharmaceutically acceptable salts, solvates or hydrates thereof; wherein, A is (C6-C10)aryl, (C6-C10)aryl-SO2, (C6-C10)aryl-CH2—, (C6-C10)arylcarbonyl, (C1-C9)heteroaryl, (C1-C9)heteroaryl-SO2—, (C1-C9)heteroaryl-CH2—; or (C1-C9)heteroarylcarbonyl; G is selected from the group consisting of: where B is (C6-C10)aryl or (C1-C9)heteroaryl, and X is CH2, SO2, or carbonyl; where X is CH2, SO2, or carbonyl; and R1 and R1? are each independently selected from H, CN, (C1-C8)alkyl-, and phenyl(CH2)—, wherein said alkyl and phenyl groups are optionally substituted; and where Z and W are as defined in the present Specificiation; and pharmaceutical compositions and methods useful to increase secretion of growth hormone(GH) from the anterior pituitary of mammals, including on a sustained release basis.
    Type: Application
    Filed: November 16, 2001
    Publication date: March 10, 2005
    Inventors: Bruce Hay, Bridget Cole, Anthony Ricketts