Patents by Inventor Bridget M. Cole

Bridget M. Cole has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triazolopyridine polymorph A
    Patent number: 11746108
    Abstract: The invention relates to a Form A polymorph of a triazolopyridine compound, pharmaceutical compositions and methods of use thereof.
    Type: Grant
    Filed: June 13, 2022
    Date of Patent: September 5, 2023
    Assignee: APM Therapeutics 1, Inc.
    Inventors: Jianmin Mao, Bridget M. Cole
  • Phthalazinone compounds and methods for the treatment of cystic fibrosis
    Patent number: 10889576
    Abstract: The invention relates to a compound of Formula I and methods of treating CFTR (cystic fibrosis transmembrane conductance regulator) mediated diseases, in particular cystic fibrosis, comprising the step of administering a therapeutically effective amount of a compound of Formula I to a patient in need thereof:
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: January 12, 2021
    Assignee: Flatley Discovery Lab, LLC
    Inventor: Bridget M. Cole
  • PYRIDAZINONE COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20200017486
    Abstract: The invention relates to a compound of having the following formulae and methods of treating cystic fibrosis:
    Type: Application
    Filed: July 15, 2019
    Publication date: January 16, 2020
    Inventors: Bridget M. Cole, Richard A. Nugent, Andrew Kolodziej, Karen Handley, Yevgen Barsukov
  • Triazolopyridine compounds and methods for the treatment of cystic fibrosis
    Patent number: 10472357
    Abstract: The invention relates to a compound of Formula I or IA and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof:
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: November 12, 2019
    Assignee: Flatley Discovery Lab, LLC
    Inventors: Bridget M. Cole, Richard A. Nugent, Paul T. Smith, Jr.
  • PHTHALAZINONE COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20190256505
    Abstract: The invention relates to a compound of Formula I and methods of treating CFTR (cystic fibrosis transmembrane conductance regulator) mediated diseases, in particular cystic fibrosis, comprising the step of administering a therapeutically effective amount of a compound of Formula I to a patient in need thereof:
    Type: Application
    Filed: April 30, 2019
    Publication date: August 22, 2019
    Inventor: Bridget M. Cole
  • Pyridazinone compounds and methods for the treatment of cystic fibrosis
    Patent number: 10370366
    Abstract: The invention relates to a compound of having the following formulae and methods of treating cystic fibrosis:
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: August 6, 2019
    Assignee: Flatley Discovery Lab, LLC
    Inventors: Bridget M. Cole, Richard A. Nugent, Andrew Kolodziej, Karen Handley, Yevgen Barsukov
  • Phthalazinone compounds and methods for the treatment of cystic fibrosis
    Patent number: 10280160
    Abstract: The invention relates to a compound of Formula I and methods of treating CFTR (cystic fibrosis transmembrane conductance regulator) mediated diseases, in particular cystic fibrosis, comprising the step of administering a therapeutically effective amount of a compound of Formula I to a patient in need thereof:
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: May 7, 2019
    Assignee: FLATLEY DISCOVERY LAB, LLC
    Inventor: Bridget M. Cole
  • Compounds and methods for the treatment of cystic fibrosis
    Patent number: 10072017
    Abstract: The invention relates to a compound of Formula I or IA compositions comprising compounds of Formula I or IA, and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof:
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: September 11, 2018
    Assignee: Flatley Discovery Lab, LLC
    Inventors: Michael P. Zawistoski, Asmita Deshpande, Bridget M. Cole
  • Triazolopyridine Compounds and Methods for the Treatment of Cystic Fibrosis
    Publication number: 20180230146
    Abstract: The invention relates to a compound of Formula I or IA and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof:
    Type: Application
    Filed: February 8, 2018
    Publication date: August 16, 2018
    Inventors: Bridget M. Cole, Richard A. Nugent, Paul T. Smith, JR.
  • Compounds and methods for the treatment of cystic fibrosis
    Patent number: 9944603
    Abstract: The invention relates to a compound of Formula I and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: April 17, 2018
    Assignee: FLATLEY DISCOVERY LAB, LLC
    Inventors: Michael P. Zawistoski, Yevgen Barsukov, Bridget M. Cole, Richard A. Nugent
  • PYRIDAZINONE COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20180093976
    Abstract: The invention relates to a compound of having the following formulae and methods of treating cystic fibrosis:
    Type: Application
    Filed: October 6, 2017
    Publication date: April 5, 2018
    Inventors: Bridget M. Cole, Richard A. Nugent, Andrew Kolodziej, Karen Handley, Yevgen Barsukov
  • Triazolopyridine compounds and methods for the treatment of cystic fibrosis
    Patent number: 9926315
    Abstract: The invention relates to a compound of Formula I or IA and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof:
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: March 27, 2018
    Assignee: Flatley Discovery Lab, LLC
    Inventors: Bridget M. Cole, Richard A. Nugent, Paul T. Smith, Jr.
  • PHTHALAZINONE COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20180044330
    Abstract: The invention relates to a compound of Formula I and methods of treating CFTR (cystic fibrosis transmembrane conductance regulator) mediated diseases, in particular cystic fibrosis, comprising the step of administering a therapeutically effective amount of a compound of Formula I to a patient in need thereof:
    Type: Application
    Filed: June 6, 2017
    Publication date: February 15, 2018
    Inventor: Bridget M. Cole
  • Isoxazole compounds and methods for the treatment of cystic fibrosis
    Patent number: 9855249
    Abstract: The invention relates to a compound of Formula I and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I or II to a patient in need thereof:
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: January 2, 2018
    Assignee: FLATLEY DISCOVERY LAB, LLC
    Inventors: Bridget M. Cole, Andrew Kolodziej
  • COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20170313659
    Abstract: The invention relates to a compound of Formula I and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof:
    Type: Application
    Filed: April 10, 2017
    Publication date: November 2, 2017
    Inventors: Michael P. Zawistoski, Yevgen Barsukov, Bridget M. Cole, Richard A. Nugent
  • Pyridazinone compounds and methods for the treatment of cystic fibrosis
    Patent number: 9790215
    Abstract: The invention relates to a compound of Formula I and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I to a patient in need thereof:
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: October 17, 2017
    Assignee: FLATLEY DISCOVERY LAB, LLC
    Inventors: Bridget M. Cole, Richard A. Nugent, Andrew Kolodziej, Karen Handley, Yevgen Barsukov
  • Pyridazinone compounds and methods for the treatment of cystic fibrosis
    Patent number: 9783529
    Abstract: The invention relates to a compound of having the following formulae and methods of treating cystic fibrosis:
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: October 10, 2017
    Assignee: FLATLEY DISCOVERY LAB, LLC
    Inventors: Bridget M. Cole, Richard A. Nugent, Andrew Kolodziej, Karen Handley, Yevgen Barsukov
  • Compounds and methods for the treatment of cystic fibrosis
    Patent number: 9771327
    Abstract: The invention relates to a compound of Formula I and methods of treating CFTR (cystic fibrosis transmembrane conductance regulator) mediated diseases, in particular cystic fibrosis, comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof:
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: September 26, 2017
    Assignee: FLATLEY DISCOVERY LAB, LLC
    Inventors: Michael P. Zawistoski, Yevgen Barsukov, Bridget M. Cole, Richard A. Nugent
  • TRIAZOLOPYRIDINE COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20170233388
    Abstract: The invention relates to a compound of Formula I or IA and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof:
    Type: Application
    Filed: January 19, 2017
    Publication date: August 17, 2017
    Inventors: Bridget M. Cole, Richard A. Nugent, Paul T. Smith, JR.
  • COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20170204110
    Abstract: The invention relates to a compound of Formula I or IA compositions comprising compounds of Formula I or IA, and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof:
    Type: Application
    Filed: December 28, 2016
    Publication date: July 20, 2017
    Inventors: Michael P. Zawistoski, Asmita Deshpande, Bridget M. Cole