Patents by Inventor BRIDGET MURPHY

BRIDGET MURPHY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC AND DIAGNOSTIC APPLICATIONS BASED ON THE ROLE OF THE CXCR-4 GENE IN TUMORIGENESIS
    Publication number: 20140072564
    Abstract: The present invention relates to the identification of a novel role of CXCR-4 in cell transformation and aberrant cellular proliferation. In particular, the present invention relates to the altered gene expression of CXCR-4 in a number of primary tumors and cell lines derived from tumors, in addition to, the altered gene expression of ligands for CXCR-4. Further, the present invention relates, in part, to the Applicants' surprising discovery that the inhibition of CXCR-4 gene expression or the inhibition of CXCR-4 activity in transformed cells reverses the transformed phenotype.
    Type: Application
    Filed: April 2, 2013
    Publication date: March 13, 2014
    Applicant: NORTHWEST BIOTHERAPEUTICS, INC.
    Inventor: Bridget Murphy
  • THERAPEUTIC AND DIAGNOSTIC APPLICATIONS BASED ON THE ROLE OF THE CXCR-4 GENE IN TUMORIGENESIS
    Publication number: 20100062003
    Abstract: The present invention relates to the identification of a novel role of CXCR-4 in cell transformation and aberrant cellular proliferation. In particular, the present invention relates to the altered gene expression of CXCR-4 in a number of primary tumors and cell lines derived from tumors, in addition to, the altered gene expression of ligands for CXCR-4. Further, the present invention relates, in part, to the Applicant's surprising discovery that the inhibition of CXCR-4 gene expression or the inhibition of CXCR-4 activity in transformed cells reverses the transformed phenotype.
    Type: Application
    Filed: February 6, 2009
    Publication date: March 11, 2010
    Applicant: NORTHWEST BIOTHERAPEUTICS, INC.
    Inventors: GERALD P. MURPHY, ALTON L. BOYNTON, ANIL SEHGAL, BRIDGET MURPHY
  • Nr-CAM gene, nucleic acids and nucleic acid products for therapeutic and diagnostic uses for tumors
    Publication number: 20060269558
    Abstract: The present invention relates to the identification of a novel role of Nr-CAM in cell transformation and aberrant cellular proliferation. In particular, the present invention relates to the altered gene expression of Nr-CAM in a number of primary tumors and cell lines derived from tumors, in addition to, the altered gene expression of ligands for Nr-CAM. Further, the present invention relates, in part, to the Applicants' surprising discovery that the inhibition of Nr-CAM gene expression or the inhibition of Nr-CAM activity in transformed cells reverses the transformed phenotype.
    Type: Application
    Filed: June 1, 2006
    Publication date: November 30, 2006
    Inventors: Gerald Murphy, Alton Boynton, Anil Sehgal, Bridget Murphy