Patents by Inventor Bridgette Murphy

Bridgette Murphy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic and diagnostic applications based on the role of the CXCR-4 gene in tumorigenesis
    Patent number: 8409566
    Abstract: The present invention relates to the identification of a novel role of CXCR-4 in cell transformation and aberrant cellular proliferation. In particular, the present invention relates to the altered gene expression of CXCR-4 in a number of primary tumors and cell lines derived from tumors, in addition to, the altered gene expression of ligands for CXCR-4. Further, the present invention relates, in part, to the Applicant's surprising discovery that the inhibition of CXCR-4 gene expression or the inhibition of CXCR-4 activity in transformed cells reverses the transformed phenotype.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: April 2, 2013
    Assignee: Northwest Biotherapeutics, Inc.
    Inventors: Alton L. Boynton, Anil Sehgal, Bridgette Murphy
  • Therapeutic and diagnostic applications based on the role of the CXCR-4 gene in tumorigenesis
    Publication number: 20050202019
    Abstract: The present invention relates to the identification of a novel role of CXCR-4 in cell transformation and aberrant cellular proliferation. In particular, the present invention relates to the altered gene expression of CXCR-4 in a number of primary tumors and cell lines derived from tumors, in addition to, the altered gene expression of ligands for CXCR-4. Further, the present invention relates, in part, to the Applicants' surprising discovery that the inhibition of CXCR-4 gene expression or the inhibition of CXCR-4 activity in transformed cells reverses the transformed phenotype.
    Type: Application
    Filed: November 9, 2004
    Publication date: September 15, 2005
    Applicant: Northwest Biotherapeutics, Inc.
    Inventors: Gerald Murphy, Alton Boynton, Anil Sehgal, Bridgette Murphy
  • Therapeutic and diagnostic applications based on the role of the CXCR-4 gene in tumorigenesis
    Patent number: 6863887
    Abstract: The present invention relates to the identification of a novel role of CXCR-4 in cell transformation and aberrant cellular proliferation. In particular, the present invention relates to the altered gene expression of CXCR-4 in a number of primary tumors and cell lines derived from tumors, in addition to, the altered gene expression of ligands for CXCR-4. Further, the present invention relates, in part, to the Applicants' surprising discovery that the inhibition of CXCR-4 gene expression or the inhibition of CXCR-4 activity in transformed cells reverses the transformed phenotype.
    Type: Grant
    Filed: March 29, 1999
    Date of Patent: March 8, 2005
    Assignee: Northwest Biotherapeutics, Inc.
    Inventors: Bridgette Murphy, Alton L. Boynton, Anil Sehgal, Gerald P. Murphy