Patents by Inventor Brigid L. M. Hogan

Brigid L. M. Hogan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS OF MAKING EMBRYONIC STEM CELLS
    Publication number: 20090170201
    Abstract: The invention relates to cell proliferation, cell differentiation, male infertility, male fertility and to compositions and methods involved therein.
    Type: Application
    Filed: May 22, 2008
    Publication date: July 2, 2009
    Applicant: VANDERBILT UNIVERSITY
    Inventors: Brigid L.M. Hogan, Guang-Quan Zhao
  • Pluripotential embryonic stem cells and methods of making same
    Patent number: 7153684
    Abstract: The present invention provides a non-mouse, including human, pluripotential embryonic stem cell which can: (a) be maintained on feeder layers for at least 20 passages; and (b) give rise to embryoid bodies and multiple differentiated cell phenotypes in monolayer culture. The invention further provides a method of making a pluripotential embryonic stem cell comprising culturing germ cells and germ cell progenitors in a composition comprising a growth enhancing amount of basic fibroblast growth factor, leukemia inhibitory factor, membrane associated steel factor, and soluble steel factor to primordial germ cells under cell growth conditions, thereby making a pluripotential embryonic stem cell. Also provided are compositions useful to produce the pluripotent embryonic stem cells and methods of screening associated with the method of making the embryonic stem cell.
    Type: Grant
    Filed: March 6, 1997
    Date of Patent: December 26, 2006
    Assignee: Vanderbilt University
    Inventor: Brigid L. M. Hogan
  • Pluripotential embryonic stem cells and methods of making same
    Publication number: 20040071672
    Abstract: The present invention provides a non-mouse, including human, pluripotential embryonic stem cell which can:
    Type: Application
    Filed: December 20, 2002
    Publication date: April 15, 2004
    Applicant: Vanderbilt University
    Inventor: Brigid L. M. Hogan
  • Compositions and methods of making embryonic stem cells
    Publication number: 20030153072
    Abstract: The invention relates to cell proliferation, cell differentiation, male infertility, male fertility and to compositions and methods involved therein.
    Type: Application
    Filed: January 24, 2003
    Publication date: August 14, 2003
    Inventors: Brigid L.M. Hogan, Guang-Quan Zhao
  • Compositions and methods of making embryonic stem cells
    Patent number: 6251671
    Abstract: The invention relates to cell proliferation, cell differentiation, male infertility, male fertility and to compositions and methods involved therein. Also methods of culturing spermatogonial stem cells with bone morphogenetic protein 8 are disclosed.
    Type: Grant
    Filed: February 28, 1997
    Date of Patent: June 26, 2001
    Assignee: Vanderbilt University
    Inventors: Brigid L. M. Hogan, Guang-Quan Zhao
  • Pluripotential embryonic cells and methods of making same
    Patent number: 5690926
    Abstract: The claimed invention is directed towards non-murine pluripotential cells that have the ability to be passaged in vitro for at least 20 passages and which differentiate in culture into a variety of tissues. The scope of the claimed cells includes any non-murine ES cells and particular claims are drawn to human pluripotential cells.
    Type: Grant
    Filed: March 25, 1994
    Date of Patent: November 25, 1997
    Assignee: Vanderbilt University
    Inventor: Brigid L. M. Hogan
  • Pluripotential embryonic stem cells and methods of making same
    Patent number: 5670372
    Abstract: The present invention provides a non-mouse pluripotential embryonic stem cell which can be maintained on feeder layers for at least 20 passages and give rise to embryoid bodies and multiple differentiated cell phenotypes in monolayer culture. The invention further provides a method of making a pluripotential embryonic stem cell comprising administering a growth enhancing amount of basic fibroblast growth factor, leukemia inhibitory factor, membrane associated steel factor, and soluble steel factor to primordial germ cells under cell growth conditions, thereby making a pluripotential embryonic stem cell.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: September 23, 1997
    Assignee: Vanderbilt University
    Inventor: Brigid L. M. Hogan
  • Pluripotential embryonic stem cells and methods of making same
    Patent number: 5453357
    Abstract: The present invention provides a non-mouse pluripotential embryonic stem cell which can:(a) be maintained on feeder layers for at least 20 passages; and(b) give rise to embryoid bodies and multiple differentiated cell phenotypes in monolayer culture. The invention further provides a method of making a pluripotential embryonic stem cell comprising administering a growth enhancing amount of basic fibroblast growth factor, leukemia inhibitory factor, membrane associated steel factor, and soluble steel factor to primordial germ cells under cell growth conditions, thereby making a pluripotential embryonic stem cell.
    Type: Grant
    Filed: October 8, 1992
    Date of Patent: September 26, 1995
    Assignee: Vanderbilt University
    Inventor: Brigid L. M. Hogan