Patents by Inventor Brigit RAUX

Brigit RAUX has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Xanthine derivatives and uses thereof as inhibitors of bromodomains of BET proteins
    Patent number: 11180510
    Abstract: The present invention relates to a compound having the following formula (I): (I) wherein: —R is a (C1-C6)alkyl group; —R? is preferably H; —Ar is a (C5-C12)arylene radical; —X1 is —C(?O)—or —SO2—; and —R? is chosen from the group consisting of possibly substituted (C1-C6)alkyl, heteroaryl, (C5-C12)aryl, and (hetero)cycloalkyl groups, or a pharmaceutically acceptable salt and/or tautomeric form thereof, or its racemates, diastereomers or enantiomers.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: November 23, 2021
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ D'AIX-MARSEILLE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Stéphane Betzi, Sébastien Combes, Yves Collette, Laurent Hoffer, Xavier Morelli, Brigit Raux, Philippe Roche, Iuliia Voitovich
  • XANTHINE DERIVATIVES AND USES THEREOF AS INHIBITORS OF BROMODOMAINS OF BET PROTEINS
    Publication number: 20200377522
    Abstract: The present invention relates to a compound having the following formula (I): (I) wherein: —R is a (C1-C6)alkyl group; —R? is preferably H; —Ar is a (C5-C12)arylene radical; —X1 is —C(?O)— or —SO2—; and —R? is chosen from the group consisting of possibly substituted (C1-C6)alkyl, heteroaryl, (C5-C12)aryl, and (hetero)cycloalkyl groups, or a pharmaceutically acceptable salt and/or tautomeric form thereof, or its racemates, diastereomers or enantiomers
    Type: Application
    Filed: November 6, 2018
    Publication date: December 3, 2020
    Inventors: Stéphane BETZI, Sébastien COMBES, Yves COLLETTE, Laurent HOFFER, Xavier MORELLI, Brigit RAUX, Philippe ROCHE, Iuliia VOITOVICH
  • XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS
    Publication number: 20190292186
    Abstract: This invention relates to xanthine derivative compounds that are inhibitors of BET bromodomains proteins, the method of preparation thereof and applications thereof.
    Type: Application
    Filed: December 27, 2016
    Publication date: September 26, 2019
    Inventors: Xavier MORELLI, Sébastien COMBES, Jean-Claude GUILLEMOT, Stéphanie BETZI, Yves COLLETTE, Philippe ROCHE, Adrein LUGARI, Sabine MILHAS, Brigit RAUX, luliia VOITOVICH