Patents by Inventor Brigitte Autran

Brigitte Autran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccination by transcutaneous targeting
    Patent number: 8956617
    Abstract: The present invention relates to a method of vaccination via hair follicles that makes it possible to target vaccine components to the antigen-presenting cells in order to induce a protective and effective immune response against pathogens.
    Type: Grant
    Filed: June 23, 2006
    Date of Patent: February 17, 2015
    Assignees: Fondation Bettencourt-Schueller, Universite Pierre et Marie Curie Paris 6, Universite Charite—Universitaetsmedizin Berlin
    Inventors: Behazine Combadiere, Annika Vogt, Ulrike Blume-Peytavi, Brigitte Autran, Christine Katlama, Hans Schaeffer
  • Method of Prognosis and/or Diagnosing an IRS in a Patient Infected with M. Tuberculosis and Optionally HIV
    Publication number: 20110311992
    Abstract: The invention relates to a method of prognosing and/or diagnosing a M. tuberculosis-Immune restoration syndrome (TB-IRS) in an individual infected with M. tuberculosis and optionally HIV comprising comparing the percentage or concentration of ??+ or ??+V?2+T-lymphocytes which express an inhibitory KIR receptor with a predetermined value.
    Type: Application
    Filed: February 5, 2010
    Publication date: December 22, 2011
    Applicant: Institut National De La Sante Et De La Recherche Medicale (INSERM)
    Inventor: Brigitte Autran
  • VACCINATION BY TRANSCUTANEOUS TARGETING
    Publication number: 20100285099
    Abstract: The present invention relates to a method of vaccination via hair follicles that makes it possible to target vaccine components to the antigen-presenting cells in order to induce a protective and effective immune response against pathogens.
    Type: Application
    Filed: June 23, 2006
    Publication date: November 11, 2010
    Applicants: FONDATION BETTENCOURT-SCHUELLER, UNIVERSITE PIERRE ET MARIE CURIE PARIS 6, UNIVERSITE CHARITE-UNVERSITAETSMEDIZIN BERLIN
    Inventors: Behazine Combadiere, Annika Vogt, Ulrike Blume-Peytavi, Brigitte Autran, Christine Katlama, Hans Schaeffer
  • Method of Diagnosis of Tuberculosis Related Immune Restoration Syndrome (IRS)
    Publication number: 20100093007
    Abstract: The present invention relates to a method and kit of diagnosis of Immune Restoration Syndrome associated with tuberculosis (TB-IRS) in patients infected with tuberculosis (TB) as well as in HIV co-infected patients comprising detecting an acute increase in Th1 response following exposure to mycobacterial extract, referred as tuberculin or PPD (Purified Protein Derivative) as well as to the 16 kDa protein, but not to ESAT-6 or CFP-10, two antigens from mycobacterium tuberculosis.
    Type: Application
    Filed: September 7, 2006
    Publication date: April 15, 2010
    Applicant: Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Brigitte Autran, Anne Bourgarit, Guislaine Carcelain, Valérie Martinez, Brigitte Gicquel, Daniel Sereni
  • Therapeutic vaccination method, mutated peptides of hiv reverse transciptase and their use for vaccination and diagnostic purposes
    Publication number: 20050074463
    Abstract: The invention concerns treatment of infectious and tumoral pathologies comprising a anti-infective and/or anti-tumoral chemotherapeutic treatment phase inducing resistance mutations and a therapeutic vaccination phase directed against said resistance mutations and the agents used in said treatment More particularly, the invention concerns peptides of 8 to 80 amino acids of the HIV reverse transcriptase sequence and comprising at least a mutation with respect to said wild sequence of said enzyme, mutation induced in response to treatments by nucleoside and non-nucleoside analogues of the HIV reverse transcriptase. The invention also concerns a pharmaceutical composition or vaccine based on said peptides, for inducing an immune response specific of said mutated sequences and for enhancing or prolonging the efficiency of treatments with nucleoside or non-nucleoside analogues of the HIV reverse transcriptase.
    Type: Application
    Filed: September 14, 2001
    Publication date: April 7, 2005
    Applicant: Universite Pierre et Marie Curie-paris VI
    Inventors: Brigitte Autran, Assia Samri, Patrice Debre, Vincent Calvez, Christine Katlama, Gaby Haas