Patents by Inventor Brigitte Demers

Brigitte Demers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LUNG CANCER COMBINATION THERAPY WITH IL-2 CONJUGATES AND AN ANTI-PD-1 ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF
    Publication number: 20230381335
    Abstract: Disclosed herein are methods for treating a lung cancer in a subject in need thereof, comprising administering IL-2 conjugates in combination with the anti-PD-1 antibody or antigen-binding fragment thereof (e.g., pembrolizumab).
    Type: Application
    Filed: August 10, 2023
    Publication date: November 30, 2023
    Inventors: Giovanni Abbadessa, Carolina E. Caffaro, Brigitte Demers, Joseph Leveque, Wan-Ju Meng, Jerod Ptacin
  • USE OF ANTI-CEACAM5 IMMUNOCONJUGATES FOR TREATING LUNG CANCER
    Publication number: 20220080053
    Abstract: The present disclosure provides methods of treating high CEACAM5 expressing cancers including lung cancers such NSQ NSCLC using immunoconjugates comprising an antibody that specifically binds human CEACAM5.
    Type: Application
    Filed: February 6, 2020
    Publication date: March 17, 2022
    Inventors: Aurore ALLARD, Mustapha CHADJAA, Cécile COMBEAU, Brigitte DEMERS, Christophe HENRY, Semra YORUK
  • ANTITUMOR COMBINATION INCLUDING AVE8062 AND SORAFENIB
    Publication number: 20120108641
    Abstract: Combinations comprising AVE8062 and sorafenib are provided which are effective in the treatment of cancers, more particularly of solid tumours.
    Type: Application
    Filed: November 3, 2011
    Publication date: May 3, 2012
    Applicant: SANOFI
    Inventors: Brigitte DEMERS, Patricia VRIGNAUD
  • Combination Comprising Combretastatin and Anticancer Agents
    Publication number: 20110054035
    Abstract: This invention relates to therapeutic combinations comprising VEGF Trap and a stilbene derivative, and to methods for treatment of cancer comprising administration of such combinations.
    Type: Application
    Filed: November 9, 2010
    Publication date: March 3, 2011
    Applicant: AVENTIS PHARMA S.A.
    Inventors: Marie-Christine BISSERY, Patricia VRIGNAUD, Marielle CHIRON-BLONDEL, Brigitte DEMERS
  • Combination comprising combretastatin and anticancer agents
    Patent number: 7851443
    Abstract: This invention relates to therapeutic combinations comprising VEGF Trap and a stilbene derivative, and to methods for treatment of cancer comprising administration of such combinations.
    Type: Grant
    Filed: June 19, 2008
    Date of Patent: December 14, 2010
    Assignee: Aventis Pharma SA
    Inventors: Marie-Christine Bissery, Patricia Vrignaud, Marielle Chiron-Blondel, Brigitte Demers
  • Combination Comprising Combretastatin and Anticancer Agents
    Publication number: 20090023656
    Abstract: This invention relates to therapeutic combinations comprising VEGF Trap and a stilbene derivative, and to methods for treatment of cancer comprising administration of such combinations.
    Type: Application
    Filed: June 19, 2008
    Publication date: January 22, 2009
    Applicant: AVENTIS PHARMA S.A.
    Inventors: Marie-Christine BISSERY, Patricia VRIGNAUD, Marielle CHIRON-BLONDEL, Brigitte DEMERS
  • Method for screening for inhibitors and activators of type III secretion machinery in gram-negative bacteria
    Patent number: 6696249
    Abstract: This invention relates to mutant strains of gram-negative bacteria that constitutively secrete proteins via the type III secretion machinery and to methods of identifying molecules that are able to activate or inhibit secretion in wild-type strains of gram-negative bacteria by exposing gram-negative bacterial cells to a sample molecule, wherein the bacterial cells contain a reporter gene transcriptionally fused to a promoter of a gene activated or regulated by the type III secretion machinery and detecting the presence or activity of the product of the reporter gene.
    Type: Grant
    Filed: February 5, 2001
    Date of Patent: February 24, 2004
    Assignees: Institut Pasteur, Institute National de la Santa et de la Recherche Medicale
    Inventors: Brigitte Demers, Philippe Sansonetti, Claude Parsot
  • Method for screening for inhibitors and activators of type III secretion machinery in gram-negative bacteria
    Patent number: 6136542
    Abstract: This invention relates to mutant strains of gram-negative bacteria that constitutively secrete proteins via the type III secretion machinery. It also relates to methods of identifying molecules that are able to activate or inhibit secretion in wild-type strains of gram-negative bacteria by exposing gram-negative bacterial cells to a sample molecule, wherein said bacterial cells contain a reporter gene transcriptionally fused to a promoter of a gene activated or regulated by the type III secretion machinery, and detecting the presence or activity of the product of the reporter gene.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: October 24, 2000
    Assignees: Institut Pasteur, Institut Nationale de la Sante et de la Recherche
    Inventors: Brigitte Demers, Philippe J. Sansonetti, Claude Parsot