Patents by Inventor Brigitte Giesinger

Brigitte Giesinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing N-(4-hydroxyphenyl)-N?-(4?-aminophenyl)-piperazine
    Patent number: 6355801
    Abstract: A process is provided for producing a compound having the formula: by: (a) reacting a compound having the formula  with a compound having the formula  in the presence of an organic base selected from the group consisting of: triethylamine; N,N-diisopropylethylamine; 1,8-diazabicyclo[5.4.0]undec-7-ene(1,5-5); 1,5-diazabicyclo[4.3.0]non-5-ene; or 1,4-diazabicyclo[2.2.2]octane to form a compound having the formula (b) reducing the compound of formula (4.0) to form the compound of formula (1.0), wherein X is Cl, Br, I or F.
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: March 12, 2002
    Assignee: Schering Corporation
    Inventors: Brigitte Giesinger, Ingrid Mergelsberg
  • Preparation of aminomethyl-phenylimidazoles
    Patent number: 5905152
    Abstract: Aminomethyl-phenylimidazoles are produced by reaction of an ester of a hydroxymethyl-phenylimidazole with an amine. A particularly preferred ester is the acetate ester. The aminomethyl-phenylimidazoles have useful properties as highly selective partial agonists or antagonists at brain dopamine receptor subtypes. A preferred compound prepared is 5-fluoro-2-?4-?(2-phenyl-1H-imidazol-5-yl)methyl!-1-piperazinyl!pyrimidine . Esters of the hydroxymethyl-phenylimidazoles are useful intermediates.
    Type: Grant
    Filed: August 6, 1997
    Date of Patent: May 18, 1999
    Assignee: Schering Corporation
    Inventors: Dinesh Gala, Ingrid Mergelsberg, Martin Steinman, Brigitte Giesinger, Dominik Scherer