Patents by Inventor Brigitte Staggl

Brigitte Staggl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Avibactam free acid
    Patent number: 11124513
    Abstract: The present invention relates to avibactam free acid, a method for preparing avibactam free acid and a method for preparing avibactam sodium by further reacting avibactam free acid. The invention further refers to a pharmaceutical composition comprising avibactam free acid, one or more alkaline sodium salt(s) and one or more beta-lactam antibiotic(s). The pharmaceutical composition of the present invention can be used as medicament, in particular for treatment and/or prevention of bacterial infections.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: September 21, 2021
    Assignee: Sandoz AG
    Inventors: Michael Fischer, Andreas Lechner, Brigitte Staggl
  • Process for the preparation of crystalline form C of avibactam sodium
    Patent number: 10919893
    Abstract: The invention relates to a process for the preparation of avibactam sodium in polymorphic form C comprising the steps (i) providing a mixture comprising avibactam or a salt thereof and a solvent, wherein the mixture has a water content of less than 2% by weight based on the weight of the mixture; (ii) increasing the temperature of the mixture provided in (i) to at least 55° C. and providing a positive pressure; adding a sodium source to the mixture in step (i) and/or (ii) if the form of avibactam provided in (i) is not avibactam sodium; thereby obtaining avibactam sodium in polymorphic form C.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: February 16, 2021
    Assignee: Sandoz AG
    Inventors: Michael Fischer, Veronika Werner, Andreas Lechner, Brigitte Staggl
  • Process for the Preparation of Crystalline Form C of Avibactam Sodium
    Publication number: 20190359612
    Abstract: The invention relates to a process for the preparation of avibactam sodium in polymorphic form C comprising the steps (i) providing a mixture comprising avibactam or a salt thereof and a solvent, wherein the mixture has a water content of less than 2% by weight based on the weight of the mixture; (ii) increasing the temperature of the mixture provided in (i) to at least 55° C. and providing a positive pressure; adding a sodium source to the mixture in step (i) and/or (ii) if the form of avibactam provided in (i) is not avibactam sodium; thereby obtaining avibactam sodium in polymorphic form C.
    Type: Application
    Filed: February 7, 2018
    Publication date: November 28, 2019
    Applicant: Sandoz AG
    Inventors: Michael Fischer, Veronika Werner, Andreas Lechner, Brigitte Staggl
  • Avibactam Free Acid
    Publication number: 20190185473
    Abstract: The present invention relates to avibactam free acid, a method for preparing avibactam free acid and a method for preparing avibactam sodium by further reacting avibactam free acid. The invention further refers to a pharmaceutical composition comprising avibactam free acid, one or more alkaline sodium salt(s) and one or more beta-lactam antibiotic(s). The pharmaceutical composition of the present invention can be used as medicament, in particular for treatment and/or prevention of bacterial infections.
    Type: Application
    Filed: August 25, 2017
    Publication date: June 20, 2019
    Applicant: Sandoz AG
    Inventors: Michael Fischer, Andreas Lechner, Brigitte Staggl