Patents by Inventor Brijeshkumar Patel
Brijeshkumar Patel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12421289Abstract: The present disclosure pertains to novel Glucagon like Peptide-1 (GLP-1) (7-37) analogs having an amino acid sequence with Leu or Ile at the C-terminal. The new analogs are potent GLP-1 agonists with reduced adverse effect and improved duration of action. The present disclosure further relates to acylated derivatives of the new analogs which have further improved potency and duration of action and are suitable for oral administration. The analogs of present disclosure may be useful in treatment of diabetes and obesity.Type: GrantFiled: November 21, 2023Date of Patent: September 23, 2025Assignee: SUN PHARMACEUTICAL INDUSTRIES LIMITEDInventors: Rajamannar Thennati, Nishith Chaturvedi, Vinod Sampatrao Burade, Pradeep Dinesh Shahi, Muthukumaran Natarajan, Ravishankara Madavati Nagaraja, Rishit Mansukhlal Zalawadia, Vipulkumar Shankarbhai Patel, Kunal Pandya, Brijeshkumar Patel, Dhiren Rameshchandra Joshi, Krunal Harishbhai Soni, Abhishek Tiwari
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Publication number: 20250277632Abstract: A rotary machine includes a rotor with a plurality of plates defining openings therebetween, a housing enclosing the rotor, and a flow restrictor. The flow restrictor includes a body attached to a plate of the plurality of plates of the rotor and extending from the rotor toward the housing. The flow restrictor also includes a plurality of extensions extending from the body toward the housing to form a groove between extensions of the plurality of extensions.Type: ApplicationFiled: February 26, 2025Publication date: September 4, 2025Inventors: Brijeshkumar Patel, Ryan Mochar, William Murray Whyte, Joanne Moore, Dougal Hogg
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Publication number: 20250277631Abstract: A rotary machine includes a rotor that is configured to rotate, a housing that encloses the rotor, and an elastomeric member that is attached to the housing. The housing includes a plate extending along the rotor, and the elastomeric member extends from the plate to form a seal with the rotor.Type: ApplicationFiled: February 26, 2025Publication date: September 4, 2025Inventors: Brijeshkumar Patel, Ryan Mochar, Gwyn Ashby, Joanne Moore, Dougal Hogg
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Publication number: 20240376175Abstract: The present disclosure pertains to novel Glucagon like Peptide-1 (GLP-1)(7-37) analogs having an amino acid sequence with Leu or Ile at the C-terminal. The new analogs are potent GLP-1 agonists with reduced adverse effect and improved duration of action. The present disclosure further relates to acylated derivatives of the new analogs which have further improved potency and duration of action and are suitable for oral administration. The analogs of present disclosure may be useful in treatment of diabetes and obesity.Type: ApplicationFiled: May 17, 2024Publication date: November 14, 2024Inventors: Rajamannar Thennati, Nishith Chaturvedi, Vinod Sampatrao Burade, Pradeep Dinesh Shahi, Muthukumaran Natarajan, Ravishankara Madavati Nagaraja, Rishit Mansukhlal Zalawadia, Vipulkumar Shankarbhai Patel, Kunal Pandya, Brijeshkumar Patel, Dhiren Rameshchandra Joshi, Krunal Harishbhai Soni, Abhishek Tiwari
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Publication number: 20240199718Abstract: The present disclosure pertains to novel Glucagon like Peptide-1 (GLP-1) (7-37) analogs having an amino acid sequence with Leu or Ile at the C-terminal. The new analogs are potent GLP-1 agonists with reduced adverse effect and improved duration of action. The present disclosure further relates to acylated derivatives of the new analogs which have further improved potency and duration of action and are suitable for oral administration. The analogs of present disclosure may be useful in treatment of diabetes and obesity.Type: ApplicationFiled: November 21, 2023Publication date: June 20, 2024Inventors: Rajamannar Thennati, Nishith Chaturvedi, Vinod Sampatrao Burade, Pradeep Dinesh Shahi, Muthukumaran Natarajan, Ravishankara Madavati Nagaraja, Rishit Mansukhlal Zalawadia, Vipulkumar Shankarbhai Patel, Kunal Pandya, Brijeshkumar Patel, Dhiren Rameshchandra Joshi, Krunal Harishbhai Soni, Abhishek Tiwari
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Patent number: 11873328Abstract: The present disclosure pertains to novel Glucagon like Peptide-1 (GLP-1) (7-37) analogs having an amino acid sequence with Leu or Ile at the C-terminal. The new analogs are potent GLP-1 agonists with reduced adverse effect and improved duration of action. The present disclosure further relates to acylated derivatives of the new analogs which have further improved potency and duration of action and are suitable for oral administration. The analogs of present disclosure may be useful in treatment of diabetes and obesity.Type: GrantFiled: August 1, 2022Date of Patent: January 16, 2024Assignee: SUN PHARMACEUTICAL INDUSTRIES LIMITEDInventors: Rajamannar Thennati, Nishith Chaturvedi, Vinod Sampatrao Burade, Pradeep Dinesh Shahi, Muthukumaran Natarajan, Ravishankara Madavati Nagaraja, Rishit Mansukhlal Zalawadia, Vipulkumar Shankarbhai Patel, Kunal Pandya, Brijeshkumar Patel, Dhiren Rameshchandra Joshi, Krunal Harishbhai Soni, Abhishek Tiwari
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Patent number: 11866477Abstract: The present disclosure pertains to novel Glucagon like Peptide-1 (GLP-1) (7-37) analogs having an amino acid sequence with Leu or Ile at the C-terminal. The new analogs are potent GLP-1 agonists with reduced adverse effect and improved duration of action. The present disclosure further relates to acylated derivatives of the new analogs which have further improved potency and duration of action and are suitable for oral administration. The analogs of present disclosure may be useful in treatment of diabetes and obesity.Type: GrantFiled: August 12, 2022Date of Patent: January 9, 2024Assignee: SUN PHARMACEUTICAL INDUSTRIES LIMITEDInventors: Rajamannar Thennati, Nishith Chaturvedi, Vinod Sampatrao Burade, Pradeep Dinesh Shahi, Muthukumaran Natarajan, Ravishankara Madavati Nagaraja, Rishit Mansukhlal Zalawadia, Vipulkumar Shankarbhai Patel, Kunal Pandya, Brijeshkumar Patel, Dhiren Rameshchandra Joshi, Krunal Harishbhai Soni, Abhishek Tiwari
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Publication number: 20220402991Abstract: The present disclosure pertains to novel Glucagon like Peptide-1 (GLP-1) (7-37) analogs having an amino acid sequence with Leu or Ile at the C-terminal. The new analogs are potent GLP-1 agonists with reduced adverse effect and improved duration of action. The present disclosure further relates to acylated derivatives of the new analogs which have further improved potency and duration of action and are suitable for oral administration. The analogs of present disclosure may be useful in treatment of diabetes and obesity.Type: ApplicationFiled: August 1, 2022Publication date: December 22, 2022Inventors: Rajamannar Thennati, Nishith Chaturvedi, Vinod Sampatrao Burade, Pradeep Dinesh Shahi, Muthukumaran Natarajan, Ravishankara Madavati Nagaraja, Rishit Mansukhlal Zalawadia, Vipulkumar Shankarbhai Patel, Kunal Pandya, Brijeshkumar Patel, Dhiren Rameshchandra Joshi, Krunal Harishbhai Soni, Abhishek Tiwari
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Publication number: 20220402992Abstract: The present disclosure pertains to novel Glucagon like Peptide-1 (GLP-1) (7-37) analogs having an amino acid sequence with Leu or Ile at the C-terminal. The new analogs are potent GLP-1 agonists with reduced adverse effect and improved duration of action. The present disclosure further relates to acylated derivatives of the new analogs which have further improved potency and duration of action and are suitable for oral administration. The analogs of present disclosure may be useful in treatment of diabetes and obesity.Type: ApplicationFiled: August 12, 2022Publication date: December 22, 2022Inventors: Rajamannar Thennati, Nishith Chaturvedi, Vinod Sampatrao Burade, Pradeep Dinesh Shahi, Muthukumaran Natarajan, Ravishankara Madavati Nagaraja, Rishit Mansukhlal Zalawadia, Vipulkumar Shankarbhai Patel, Kunal Pandya, Brijeshkumar Patel, Dhiren Rameshchandra Joshi, Krunal Harishbhai Soni, Abhishek Tiwari
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Patent number: 11485766Abstract: The present disclosure pertains to novel Glucagon like Peptide-1 (GLP-1) (7-37) analogs having an amino acid sequence with Leu or Ile at the C-terminal. The new analogs are potent GLP-1 agonists with reduced adverse effect and improved duration of action. The present disclosure further relates to acylated derivatives of the new analogs which have further improved potency and duration of action and are suitable for oral administration. The analogs of present disclosure may be useful in treatment of diabetes and obesity.Type: GrantFiled: December 28, 2020Date of Patent: November 1, 2022Assignee: SUN PHARMACEUTICAL INDUSTRIES LIMITEDInventors: Rajamannar Thennati, Nishith Chaturvedi, Vinod Sampatrao Burade, Pradeep Dinesh Shahi, Muthukumaran Natarajan, Ravishankara Madavati Nagaraja, Rishit Mansukhlal Zalawadia, Vipulkumar Shankarbhai Patel, Kunal Pandya, Brijeshkumar Patel, Dhiren Rameshchandra Joshi, Krunal Harishbhai Soni, Abhishek Tiwari
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Patent number: 11447535Abstract: The present disclosure pertains to novel Glucagon like Peptide-1 (GLP-1) (7-37) analogs having an amino acid sequence with Leu or Ile at the C-terminal. The new analogs are potent GLP-1 agonists with reduced adverse effect and improved duration of action. The present disclosure further relates to acylated derivatives of the new analogs which have further improved potency and duration of action and are suitable for oral administration. The analogs of present disclosure may be useful in treatment of diabetes and obesity.Type: GrantFiled: April 5, 2019Date of Patent: September 20, 2022Assignee: Sun Pharmaceutical Industries LimitedInventors: Rajamannar Thennati, Nishith Chaturvedi, Vinod Sampatrao Burade, Pradeep Dinesh Shahi, Muthukumaran Natarajan, Ravishankara Madavati Nagaraja, Rishit Mansukhlal Zalawadia, Vipulkumar Shankarbhai Patel, Kunal Pandya, Brijeshkumar Patel, Dhiren Rameshchandra Joshi, Krunal Harishbhai Soni, Abhishek Tiwari
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Patent number: 11242373Abstract: The present disclosure pertains to novel Glucagon like Peptide-1 (GLP-1) (7-37) analogs having an amino acid sequence with Leu or Ile at the C-terminal. The new analogs are potent GLP-1 agonists with reduced adverse effect and improved duration of action. The present disclosure further relates to acylated derivatives of the new analogs which have further improved potency and duration of action and are suitable for oral administration. The analogs of present disclosure may be useful in treatment of diabetes and obesity.Type: GrantFiled: August 4, 2020Date of Patent: February 8, 2022Assignee: Sun Pharmaceutical Industries LimitedInventors: Rajamannar Thennati, Nishith Chaturvedi, Vinod Sampatrao Burade, Pradeep Dinesh Shahi, Muthukumaran Natarajan, Ravishankara Madavati Nagaraja, Rishit Mansukhlal Zalawadia, Vipulkumar Shankarbhai Patel, Kunal Pandya, Brijeshkumar Patel, Dhiren Rameshchandra Joshi, Krunal Harishbhai Soni, Abhishek Tiwari
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Publication number: 20210206823Abstract: The present disclosure pertains to novel Glucagon like Peptide-1 (GLP-1) (7-37) analogs having an amino acid sequence with Leu or Ile at the C-terminal. The new analogs are potent GLP-1 agonists with reduced adverse effect and improved duration of action. The present disclosure further relates to acylated derivatives of the new analogs which have further improved potency and duration of action and are suitable for oral administration. The analogs of present disclosure may be useful in treatment of diabetes and obesity.Type: ApplicationFiled: December 28, 2020Publication date: July 8, 2021Inventors: Rajamannar Thennati, Nishith Chaturvedi, Vinod Sampatrao Burade, Pradeep Dinesh Shahi, Muthukumaran Natarajan, Ravishankara Madavati Nagaraja, Rishit Mansukhlal Zalawadia, Vipulkumar Shankarbhai Patel, Kunal Pandya, Brijeshkumar Patel, Dhiren Rameshchandra Joshi, Krunal Harishbhai Soni, Abhishek Tiwari
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Patent number: 11046744Abstract: The present disclosure pertains to novel Glucagon like Peptide-1 (GLP-1) (7-37) analogs having an amino acid sequence with Leu or Ile at the C-terminal. The new analogs are potent GLP-1 agonists with reduced adverse effect and improved duration of action. The present disclosure further relates to acylated derivatives of the new analogs which have further improved potency and duration of action and are suitable for oral administration. The analogs of present disclosure may be useful in treatment of diabetes and obesity.Type: GrantFiled: August 4, 2020Date of Patent: June 29, 2021Assignee: Sun Pharmaceutical Industries LimitedInventors: Rajamannar Thennati, Nishith Chaturvedi, Vinod Sampatrao Burade, Pradeep Dinesh Shahi, Muthukumaran Natarajan, Ravishankara Madavati Nagaraja, Rishit Mansukhlal Zalawadia, Vipulkumar Shankarbhai Patel, Kunal Pandya, Brijeshkumar Patel, Dhiren Rameshchandra Joshi, Krunal Harishbhai Soni, Abhishek Tiwari
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Publication number: 20200362007Abstract: The present disclosure pertains to novel Glucagon like Peptide-1 (GLP-1) (7-37) analogs having an amino acid sequence with Leu or Ile at the C-terminal. The new analogs are potent GLP-1 agonists with reduced adverse effect and improved duration of action. The present disclosure further relates to acylated derivatives of the new analogs which have further improved potency and duration of action and are suitable for oral administration. The analogs of present disclosure may be useful in treatment of diabetes and obesity.Type: ApplicationFiled: August 4, 2020Publication date: November 19, 2020Inventors: Rajamannar Thennati, Nishith Chaturvedi, Vinod Sampatrao Burade, Pradeep Dinesh Shahi, Muthukumaran Natarajan, Ravishankara Madavati Nagaraja, Rishit Mansukhlal Zalawadia, Vipulkumar Shankarbhai Patel, Kunal Pandya, Brijeshkumar Patel, Dhiren Rameshchandra Joshi, Krunal Harishbhai Soni, Abhishek Tiwari
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Publication number: 20190309040Abstract: The present disclosure pertains to novel Glucagon like Peptide-1 (GLP-1) (7-37) analogs having an amino acid sequence with Leu or Ile at the C-terminal. The new analogs are potent GLP-1 agonists with reduced adverse effect and improved duration of action. The present disclosure further relates to acylated derivatives of the new analogs which have further improved potency and duration of action and are suitable for oral administration. The analogs of present disclosure may be useful in treatment of diabetes and obesity.Type: ApplicationFiled: April 5, 2019Publication date: October 10, 2019Inventors: Rajamannar Thennati, Nishith Chaturvedi, Vinod Sampatrao Burade, Pradeep Dinesh Shahi, Muthukumaran Natarajan, Ravishankara Madavati Nagaraja, Rishit Mansukhlal Zalawadia, Vipulkumar Shankarbhai Patel, Kunal Pandya, Brijeshkumar Patel, Dhiren Rameshchandra Joshi, Krunal Harishbhai Soni, Abhishek Tiwari
