Patents by Inventor Brijnath P. Chaurasia

Brijnath P. Chaurasia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLID STATE FORMS OF BALOXAVIR MARBOXIL
    Publication number: 20220153753
    Abstract: The present disclosure relates to solid state forms of baloxavir marboxil, processes for preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: March 5, 2020
    Publication date: May 19, 2022
    Inventors: Anantha Rajmohan Muthusamy, Amit Singh, Amol Gulab Khatik, Sundara Lakshmi Kanniah, Yogesh Dhananjay Wagh, Parven Kumar Luthra, Brijnath P. Chaurasia, Ram Karan Prajapati
  • Solid state forms of sofosbuvir
    Patent number: 10214553
    Abstract: The present disclosure encompasses solid state forms of Sofosbuvir, processes for their production, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: June 12, 2015
    Date of Patent: February 26, 2019
    Assignees: TEVA PHARMACEUTICALS INTERNATIONAL GMBH, RATIOPHARM GMBH
    Inventors: Wolfgang Albrecht, Judith Aronhime, Brijnath P. Chaurasia, Jens Geier, Richard Guserle, Julia Hrakovsky, Claudia Lauer, Ramkaran Prajapati, Vinod K. Kansal, Pavan V. Kumar, Hans-Juergen Mika, Siva Rama Krishna Muppalla, Marina Ratkaj, Roman Safonov, Dirk Schenk, Naveen C. Srivastav, Ralph Stefan, Ashish Tripathi
  • SOLID STATE FORMS OF SOFOSBUVIR
    Publication number: 20170137453
    Abstract: The present disclosure encompasses solid state forms of Sofosbuvir, processes for their production, and pharmaceutical compositions thereof.
    Type: Application
    Filed: June 12, 2015
    Publication date: May 18, 2017
    Applicant: ratiopharm GmbH
    Inventors: Wolfgang ALBRECHT, Judith ARONHIME, Brijnath P. CHAURASIA, Jens GEIER, Richard GUSERLE, Julia HRAKOVSKY, Claudia LAUER, Ramkaran PRAJAPATI, Vinod K. KANSAL, Pavan V. KUMAR, Hans-Juergen MIKA, Siva Rama Krishna MUPPALLA, Marina RATKAJ, Roman SAFONOV, Dirk SCHENK, Naveen C. SRIVASTAV, Ralph STEFAN, Ashish TRIPATHI
  • Asymmetric synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid
    Patent number: 8212071
    Abstract: The invention encompasses processes for the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, and intermediates of (S)-Pregabalin.
    Type: Grant
    Filed: November 4, 2008
    Date of Patent: July 3, 2012
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, V. Govardhan Rao, Anand Prakash Tiwari
  • Synthesis of (S)-(+)-3-(aminomethyl)-5-methyl hexanoic acid
    Patent number: 8097754
    Abstract: Provided are syntheses of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin via a chiral intermediate of the following formula 4 wherein Ar is a C6-10 aromatic group, R is a straight or branched C1-4 alkyl, ester, or carboxylic acid, and R1 is a straight or branched C1-5 alkyl, aralkyl, or substituted aralkyl.
    Type: Grant
    Filed: March 24, 2008
    Date of Patent: January 17, 2012
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, Anand Prakash Tiwari, Shivaji Haribhau Shelke
  • Asymmetric synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid
    Patent number: 7973196
    Abstract: The invention encompasses processes for the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, and intermediates of (S)-Pregabalin.
    Type: Grant
    Filed: August 30, 2010
    Date of Patent: July 5, 2011
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, V. Govardhan Rao, Anand Prakash Tiwari
  • Process for preparing intermediates of HMG-CoA reductase inhibitors
    Patent number: 7964748
    Abstract: The present invention relates to intermediates of rosuvastatin and processes for the production thereof.
    Type: Grant
    Filed: February 4, 2010
    Date of Patent: June 21, 2011
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, Hitesh K. Patel, Vrajlal Gothalia, Hiren Gandhi
  • Asymmetric synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid
    Patent number: 7960583
    Abstract: The invention encompasses processes for the synthesis of (S)-(+)-3-(aminomethyl) -5-methylhexanoic acid, (S)-Pregabalin, and intermediates of (S)-Pregabalin.
    Type: Grant
    Filed: October 28, 2008
    Date of Patent: June 14, 2011
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, V. Govardhan Rao, Anand Prakash Tiwari
  • Asymmetric synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid
    Patent number: 7923575
    Abstract: The invention encompasses processes for the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, and intermediates of (S)-Pregabalin.
    Type: Grant
    Filed: October 19, 2009
    Date of Patent: April 12, 2011
    Assignee: Teva Pharmaceutical Industries Limited
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, V. Govardhan Rao, Anand Prakash Tiwari
  • NOVEL ASYMMETRIC SYNTHESIS OF (S)-(+)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID
    Publication number: 20100324307
    Abstract: The invention encompasses processes for the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, and intermediates of (S)-Pregabalin.
    Type: Application
    Filed: August 30, 2010
    Publication date: December 23, 2010
    Inventors: Vinod Kumar KANSAL, Brijnath P. Chaurasia, V. Govardhan Rao, Anand Prakash Tiwari
  • Asymmetric synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid
    Patent number: 7851651
    Abstract: (S)-Pregabalin, which has the chemical name (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, is useful in anticonvulsant therapy, primarily due a mechanism that serves to promote the production of gamma-amino butyric acid, an inhibitory neurotransmitter. The invention encompasses new processes for synthesizing (S)-Pregabalin. The invention also comprises certain new compounds that are useful synthetic intermediates in the synthesis of (S)-Pregabalin.
    Type: Grant
    Filed: October 28, 2008
    Date of Patent: December 14, 2010
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, V. Govardhan Rao, Anand Prakash Tiwari
  • PROCESS FOR PREPARING INTERMEDIATES OF HMG-CoA REDUCTASE INHIBITORS
    Publication number: 20100160663
    Abstract: The present invention relates to intermediates of rosuvastatin and processes for the production thereof.
    Type: Application
    Filed: February 4, 2010
    Publication date: June 24, 2010
    Inventors: Vinod Kumar KANSAL, Brijnath P. CHAURASIA, Hitesh K. PATEL, Vrajlal GOTHALIA, Hiren GANDHI
  • Novel asymmetric synthesis of (s)-(+)-3-(AMINOMETHYL)-5- methylhexanoic acid
    Publication number: 20100081841
    Abstract: The invention encompasses processes for the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, and intermediates of (S)-Pregabalin.
    Type: Application
    Filed: October 19, 2009
    Publication date: April 1, 2010
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, V. Govardhan Rao, Anand Prakash Tiwari
  • Process for preparing intermediates of HMG-CoA reductase inhibitors
    Patent number: 7687660
    Abstract: The present invention relates to intermediates of rosuvastatin and processes for the production thereof.
    Type: Grant
    Filed: April 18, 2008
    Date of Patent: March 30, 2010
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, Hitesh K. Patel, Vrajlal Gothalia, Hiren Gandhi
  • Asymmetric synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid
    Patent number: 7687656
    Abstract: The invention encompasses processes for the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, and intermediates of (S)-Pregabalin.
    Type: Grant
    Filed: October 28, 2008
    Date of Patent: March 30, 2010
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, V. Govardhan Rao, Anand Prakash Tiwari
  • Asymmetric synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid
    Patent number: 7586005
    Abstract: The invention encompasses processes for the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, and intermediates of (S)-Pregabalin.
    Type: Grant
    Filed: October 28, 2008
    Date of Patent: September 8, 2009
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, V. Govardhan Rao, Anand Prakash Tiwari
  • Process for preparing intermediates of HMG-CoA reductase inhibitors
    Publication number: 20090209779
    Abstract: The present invention relates to intermediates of rosuvastatin and processes for the production thereof.
    Type: Application
    Filed: April 21, 2009
    Publication date: August 20, 2009
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, Hitesh K. Patel, Vrajlal Gothalia, Hiren Gandhi
  • Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the synthesis of (S)-Pregabalin
    Patent number: 7563923
    Abstract: The invention encompasses the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, via the intermediate, (3R)-5-methyl-3-(2-oxo-2{[(1R)-1-phenylethyl]amino}ethyl)hexanoic acid.
    Type: Grant
    Filed: September 19, 2006
    Date of Patent: July 21, 2009
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, Anand Prakash Tiwari
  • Process for synthesis of pyrrole derivative, an intermediate for atorvastatin
    Publication number: 20090081801
    Abstract: The present invention also relates to a novel impurity, (6-{2-[2-(6-{2-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxan-4-yl)-acetylamino]-ethyl}-2,2-dimethyl-[1,3]-dioxan-4-yl)-acetic acid tert-butyl ester, the compound of formula IV, having the following structure: The present invention also provides methods of preparing the compound of formula IV as well as methods of using the compound of formula IV as a reference marker and a reference standard.
    Type: Application
    Filed: August 15, 2008
    Publication date: March 26, 2009
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, Hitesh K. Patel, V. Govardhan Rao, Vaibhav S. Daund
  • Process for preparing intermediates of HMG-CoA reductase inhibitors
    Publication number: 20090076271
    Abstract: The present invention relates to intermediates of rosuvastatin and processes for the production thereof.
    Type: Application
    Filed: April 18, 2008
    Publication date: March 19, 2009
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, Hitesh K. Patel, Vrajlal Gothalia, Hiren Gandhi