Patents by Inventor Briony Forbes

Briony Forbes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Altered insulin-like growth factor binding proteins
    Publication number: 20090075876
    Abstract: Altered IGFBPs are able to bind IGF, but the release is inhibited by resistance to protease cleavage and/or reduced binding to extracellular matrix (ECM). Alterations have been made in IGFBP-2 to the linker domain in particular and to two amino acid motifs found to be important for ECM binding. IGF-1 mediated proliferation of cancer cells have been inhibited by use of the altered IGFBPs.
    Type: Application
    Filed: February 29, 2008
    Publication date: March 19, 2009
    Inventor: Briony Forbes
  • Altered insulin-like growth factor binding proteins
    Patent number: 7488798
    Abstract: Altered IGFBPs are able to bind IGF, but the release is inhibited by resistance to protease cleavage and/or reduced binding to extracellular matrix (ECM). Alterations have been made in IGFBP-2 to the linker domain in particular and to two amino acid motifs found to be important for ECM binding. IGF-1 mediated proliferation of cancer cells have been inhibited by use of the altered IGFBPs.
    Type: Grant
    Filed: July 11, 2003
    Date of Patent: February 10, 2009
    Assignee: University of Adelaide
    Inventor: Briony Forbes
  • Altered insulin-like grwoth factor binding proteins
    Publication number: 20060153853
    Abstract: Altered IGFBPs are able to bind IGF, but the release is inhibited by resistance to protease cleavage and/or reduced binding to extracellular matrix (ECM). Alterations have been made in IGFBP-2 to the linker domain in particular and to two amino acid motifs found to be important for ECM binding. IGF-1 mediated proliferation of cancer cells have been inhibited by use of the altered IGFBPs.
    Type: Application
    Filed: July 11, 2003
    Publication date: July 13, 2006
    Applicant: THE UNIVERSITY OF ADELAIDE
    Inventor: Briony Forbes