Patents by Inventor Brit Corneliussen

Brit Corneliussen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acetyl CoA Carboxylase Splice Variant and Uses Thereof
    Publication number: 20080003227
    Abstract: The present invention relates to an isolated nucleic acid molecule comprising a nucleotide sequence that encodes an acetyl CoA carboxylase 2 (ACC2) splice variant. It also relates the corresponding polypeptide encoded by said nucleic acid and to methods of identifying a compound potentially useful for treating diseases or disorders associated with impaired ability to oxidise fatty acids, which comprises assaying the compound for its ability to modulate the activity or amount of a ACC2 splice variant complex or a complex thereof.
    Type: Application
    Filed: July 6, 2005
    Publication date: January 3, 2008
    Applicant: ASTRAZENECA AB
    Inventors: John Clapham, Brit Corneliussen, Stefan Hallen
  • Method for diagnosing inflammatory bowel disease
    Publication number: 20060100132
    Abstract: The present invention relates to a method for identifying a compound capable of modulating the action of the DLG5 protein which method comprises subjecting one or more test compounds to a screen comprising a polypeptide containing the amino acid sequence shown in SEQ ID NO: 2, or a homologue thereof or a fragment of either. Such compounds may be useful in the treatment of inflammatory bowel disease. The present invention also relates to a method for diagnosing inflammatory bowel disease by detecting variant DLG5.
    Type: Application
    Filed: June 3, 2004
    Publication date: May 11, 2006
    Inventors: Brit Corneliussen, Stefan Schreiber, Monika Stoll