Patents by Inventor Broder Ruehmann

Broder Ruehmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the enzymatic production of C4 compounds from C6 substrates
    Patent number: 9169500
    Abstract: The present invention relates to a novel process for converting a substrate of formula (III) and/or (IV) into a product of formula (I) or (II) comprising the following reactions: a) oxidation of at least one terminal C-atom, b) dehydratation, c) decarboxylation and d) reduction and/or amination. At least step b is enzyme-catalyzed. In a preferred embodiment, all reactions are enzymatically catalyzed. The enzymes catalyzing the reactions are selected from oxidoreductases, decarboxylases, dehydratases and/or aminotransferases. The process may be performed in a cell-free in vitro production system or in an improved fermentative production system.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: October 27, 2015
    Inventors: Volker Sieber, André Pick, Broder Rühmann
  • Method for producing multicyclical ring systems carrying amino groups
    Patent number: 8841096
    Abstract: The invention relates to a method for the amination of at least one keto group in a multicyclic ring system comprising at least one keto group into an amino group, using at least one enzyme E having transaminase activity.
    Type: Grant
    Filed: January 13, 2010
    Date of Patent: September 23, 2014
    Assignee: Evonik Degussa GmbH
    Inventors: Volker Sieber, Katrin Grammann, Broder Ruehmann, Thomas Haas, Jan Christoph Pfeffer, Kai Doderer, Claudia Rollmann, Arne Skerra, Christian Rausch, Alexandra Lerchner
  • PROCESS FOR THE ENZYMATIC PRODUCTION OF C4 COMPOUNDS FROM C6 SUBSTRATES
    Publication number: 20140171683
    Abstract: The present invention relates to a novel process for converting a substrate of formula (III) and/or (IV) into a product of formula (I) or (II) comprising the following reactions: a) oxidation of at least one terminal C-atom, b) dehydratation, c) decarboxylation and d) reduction and/or amination. At least step b is enzyme-catalyzed. In a preferred embodiment, all reactions are enzymatically catalyzed. The enzymes catalyzing the reactions are selected from oxidoreductases, decarboxylases, dehydratases and/or aminotransferases. The process may be performed in a cell-free in vitro production system or in an improved fermentative production system.
    Type: Application
    Filed: March 26, 2012
    Publication date: June 19, 2014
    Inventors: Volker Sieber, André Pick, Broder Rühmann
  • METHOD FOR PRODUCING MULTICYCLICAL RING SYSTEMS CARRYING AMINO GROUPS
    Publication number: 20120041216
    Abstract: The invention relates to a method for the amination of at least one keto group in a multicyclic ring system comprising at least one keto group into an amino group, using at least one enzyme E having transaminase activity.
    Type: Application
    Filed: January 13, 2010
    Publication date: February 16, 2012
    Applicant: EVONIK DEGUSSA GmbH
    Inventors: Volker Sieber, Katrin Grammann, Broder Ruehmann, Thomas Haas, Jan Christoph Pfeffer, Kai Doderer, Claudia Rollmann, Arne Skerra, Christian Rausch, Alexandra Lerchner