Patents by Inventor Bruce A. Barner

Bruce A. Barner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8497303
    Abstract: A method to enhance solubility of an active compound comprises combining an active compound, having an aqueous solubility that is less than or equal to about 10 mg/mL, and an amount of methoxypolyethylene glycol that is sufficient to increase the aqueous solubility of the active compound. Enhancement of aqueous solubility for this combination may be significantly greater than that of an active compound in combination with an equivalent amount of polyethylene glycol. Particularly enhanced solubility is shown where a small amount of water is also included. The invention may be used in a wide variety of applications, such as for pharmaceutical, agricultural, antimicrobial, and personal care products.
    Type: Grant
    Filed: January 5, 2009
    Date of Patent: July 30, 2013
    Assignee: Dow Global Technologies LLC
    Inventors: David B. Wurn, David A. Wilson, Bruce A. Barner, Cynthia L. Rand, Matthew D. Miller, Michael J. Johnson
  • Publication number: 20100288167
    Abstract: Provided is a process for preparing low diol content monofunctional polyalkylene glycols. The process includes introducing the initiator feed in two portions (a first and second initiator) and drying only the first initiator to remove water. The first and second initiators can be the same or different. Also provided are new monofunctional polyalkylene glycol compositions.
    Type: Application
    Filed: January 7, 2009
    Publication date: November 18, 2010
    Inventors: David B. Wurm, Robert H. Whitmarsh, Peirre T. Varineau, Bruce A. Barner, John G. Pendergast, JR., Kirk R. Thompson
  • Publication number: 20100286277
    Abstract: A method to enhance solubility of an active compound comprises combining an active compound, having an aqueous solubility that is less than or equal to about 10 mg/mL, and an amount of methoxypolyethylene glycol that is sufficient to increase the aqueous solubility of the active compound. Enhancement of aqueous solubility for this combination may be significantly greater than that of an active compound in combination with an equivalent amount of polyethylene glycol. Particularly enhanced solubility is shown where a small amount of water is also included. The invention may be used in a wide variety of applications, such as for pharmaceutical, agricultural, antimicrobial, and personal care products.
    Type: Application
    Filed: January 5, 2009
    Publication date: November 11, 2010
    Inventors: David B. Wurm, David A. Wilson, Bruce A. Barner, Cynthia L. Rand, Matthew D. Miller, Michael J. Johnson
  • Patent number: 5430194
    Abstract: The present invention relates to a process for producing an optically active aldehyde (first aldehyde) containing a reduced amount of the corresponding enantiomeric aldehyde (second aldehyde) which process comprises: (1) providing an initial solution containing a non-eutectic mixture of the first aldehyde and the second aldehyde, which mixture has a composition in the compositional region where only the first aldehyde crystallizes when its solubility limit in the solution is exceeded, and (2) maintaining the solution at a temperature above the eutectic temperature of the mixture and under conditions such that the solubility limit of the first aldehyde is exceeded so as to form a crystalline first aldehyde containing relatively less of the second aldehyde than was present in the initial solution.
    Type: Grant
    Filed: June 24, 1994
    Date of Patent: July 4, 1995
    Assignee: Union Carbide Chemicals & Plastics Technology Corporation
    Inventors: Bruce A. Barner, John R. Briggs, Jonathan J. Kurland, Charles G. Moyers, Jr.