Abstract: Methods of generating novel guide nucleic acids comprising a template-conserved target complementary region to a template and template-randomized region, novel guide nucleic acids generated by the methods, mixtures and complexes comprising the novel guide nucleic acids are disclosed.

Abstract: A tunable imaging sensor includes a housing with four lenses mounted on a front side. A removable or rotatable filter plate/wheel fits inside the enclosure adjacent the lenses, with a camera plate holding four CMOS or CCD imagers fitting inside the enclosure adjacent the filter plate/wheel. The filter plate includes four filters, one for each lens, while the filter wheel includes sixteen filters which are rotated into position so that four filters are always aligned with the lenses and imagers. Rotating the filter wheel provides sixteen different filter combinations for the sensor. The images from each of the imagers are processed to form a composite image.

Abstract: A tunable imaging sensor includes a housing with four lenses mounted on a front side. A removable or rotatable filter plate/wheel fits inside the enclosure adjacent the lenses, with a camera plate holding four CMOS or CCD imagers fitting inside the enclosure adjacent the filter plate/wheel. The filter plate includes four filters, one for each lens, while the filter wheel includes sixteen filters which are rotated into position so that four filters are always aligned with the lenses and imagers. Rotating the filter wheel provides sixteen different filter combinations for the sensor. The images from each of the imagers are processed to form a composite image.

Abstract: An underwater gun comprises a multi-chambered head attached to a long handle. The handle includes a rotatable section connected to the head to manually index the cylinder, sequentially chamber by chamber, into the firing position. Spring urged arms retain the cylinder in the head but with the turn of a cylinder lock ring open to permit removal and replacement of the cylinder underwater as well as above. Cartridges are held securely in the cylinder and replacement cylinders by threaded shell retainers. The extra pre-loaded cylinders can be carried by the diver underwater to reload the gun after the first cylinder has been emptied.

Abstract: A method for mixing hydrocarbons in a underground storage cavern using immiscible fluids is disclosed.