Patents by Inventor Bruce A. Chabner

Bruce A. Chabner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibodies specific for human thymidylate synthase
    Patent number: 6221620
    Abstract: The present invention relates to monoclonal antibodies that are specific for the protein thymidylate synthase, and hybridomas producing these monoclonal antibodies. The invention further relates to methods of detection and diagnostic kits to test for the presence of thymidylate synthase. The invention also relates to the use of the monoclonal antibodies in determining the presence of colon carcinoma cells.
    Type: Grant
    Filed: April 24, 1991
    Date of Patent: April 24, 2001
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Patrick G. Johnston, Carmen J. Allegra, Bruce A. Chabner, Chi-Ming Liang
  • Use of trimetrexate as antiparasitic agent
    Patent number: 4694007
    Abstract: A method of treating infections of Toxoplasmosis or P. carini comprising administering to the host an effective amount of trimetrexate, (2,4-diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline.
    Type: Grant
    Filed: May 20, 1986
    Date of Patent: September 15, 1987
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Carmen Allegra, James C. Drake, Bruce A. Chabner, Henry Masur, Joseph A. Kovacs