Patents by Inventor Bruce Alan Keyt

Bruce Alan Keyt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Constant chain modified bispecific, penta- and hexavalent Ig-M antibodies
    Patent number: 10351631
    Abstract: The present invention concerns binding molecules having a penta- or hexameric ring structure, such as, for example, isolated IgM antibodies with five or six bispecific binding units, and methods and means for making and using the same. The invention further concerns multi-specific binding molecules having a penta- or hexameric ring structure, such as, for example, isolated IgM antibodies with five or six bispecific binding units, and methods and means for making and using the same.
    Type: Grant
    Filed: September 4, 2014
    Date of Patent: July 16, 2019
    Assignee: IGM BIOSCIENCES, INC.
    Inventors: Bruce Alan Keyt, Fen Zhang, Leonard George Presta, Rency Yoshimura
  • MODIFIED J-CHAIN
    Publication number: 20190002566
    Abstract: The present invention concerns modified recombinant J-chain polypeptides, binding molecules, such as antibodies comprising the same, and their uses.
    Type: Application
    Filed: September 19, 2018
    Publication date: January 3, 2019
    Inventors: Bruce Alan Keyt, Leonard George Presta, Fen Zhang, Ramesh Baliga
  • Tumor necrosis factor (TNF) superfamily receptor IgM antibodies and uses thereof
    Patent number: 9938347
    Abstract: This disclosure provides dimeric, pentameric, and hexameric Tumor Necrosis Factor (TNF) superfamily receptor protein binding molecules and methods of using such binding molecules to direct apoptosis-mediated killing of TNF receptor-expressing cells.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: April 10, 2018
    Assignee: IGM BIOSCIENCES A/S
    Inventors: Beatrice Tien-Yi Wang, Max Allen Schwarzer, Bruce Alan Keyt, Ramesh Baliga
  • TUMOR NECROSIS FACTOR (TNF) SUPERFAMILY RECEPTOR BINDING MOLECULES AND USES THEREOF
    Publication number: 20170320955
    Abstract: This disclosure provides dimeric, pentameric, and hexameric Tumor Necrosis Factor (TNF) superfamily receptor protein binding molecules and methods of using such binding molecules to direct apoptosis-mediated killing of TNF receptor-expressing cells.
    Type: Application
    Filed: June 30, 2017
    Publication date: November 9, 2017
    Inventors: Beatrice Tien-Yi Wang, Max Allen Schwarzer, Bruce Alan Keyt, Ramesh Baliga