Patents by Inventor Bruce Albert Malcolm

Bruce Albert Malcolm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polyinosinic-polycytidylic acid (poly (I:C)) formulations for the treatment of upper respiratory tract infections
    Patent number: 10485816
    Abstract: The present invention concerns a composition comprising micro particles of polyinosinic-polycytidylic acid (Poly (I:C)) and a carrier polymer selected from starch, alginate, blanose or DPPC (dipalmitoylphosphatidylcholine) for use in preventing and/or treating viral infections of the upper respiratory tract or the common cold and a device, preferably a nasal delivery system, comprising said composition for use by a patient in need to prevent and/or treat infections or the common cold.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: November 26, 2019
    Assignee: Janssen Sciences Ireland UC
    Inventors: Lieven Elvire Colett Baert, Bruce Albert Malcolm, Roger Paulus Maria Sutmuller
  • POLYINOSINIC-POLYCYTIDYLIC ACID (POLY (I:C)) FORMULATIONS FOR THE TREATMENT OF UPPER RESPIRATORY TRACT INFECTIONS
    Publication number: 20180325939
    Abstract: The present invention concerns a composition comprising micro particles of polyinosinic-polycytidylic acid (Poly (I:C)) and a carrier polymer selected from starch, alginate, blanose or DPPC (dipalmitoylphosphatidylcholine) for use in preventing and/or treating viral infections of the upper respiratory tract or the common cold and a device, preferably a nasal delivery system, comprising said composition for use by a patient in need to prevent and/or treat infections or the common cold.
    Type: Application
    Filed: May 7, 2018
    Publication date: November 15, 2018
    Inventors: Lieven Elvire Colett Baert, Bruce Albert Malcolm, Roger Paulus Maria Sutmuller
  • Polyinosinic-polycytidylic acid (poly (I:C)) formulations for the treatment of upper respiratory tract infections
    Patent number: 9987300
    Abstract: The present invention concerns a composition comprising micro particles of polyinosinic-polycytidylic acid (Poly (I:C)) and a carrier polymer selected from starch, alginate, blanose or DPPC (dipalmitoylphosphatidylcholine) for use in preventing and/or treating viral infections of the upper respiratory tract or the common cold and a device, preferably a nasal delivery system, comprising said composition for use by a patient in need to prevent and/or treat infections or the common cold.
    Type: Grant
    Filed: June 13, 2016
    Date of Patent: June 5, 2018
    Assignee: Janssen Sciences Ireland UC
    Inventors: Lieven Elvire Colett Baert, Bruce Albert Malcolm, Roger Paulus Maria Sutmuller
  • Polyinosinic-polycytidylic acid (poly (I:C)) formulations for the treatment of upper respiratory tract infections
    Patent number: 9682096
    Abstract: The present invention concerns a composition comprising micro particles of polyinosinic-polycytidylic acid (Poly (I:C)) and a carrier polymer selected from starch, alginate, blanose or DPPC (dipalmitoylphosphatidylcholine) for use in preventing and/or treating viral infections of the upper respiratory tract or the common cold and a device, preferably a nasal delivery system, comprising said composition for use by a patient in need to prevent and/or treat infections or the common cold.
    Type: Grant
    Filed: May 2, 2013
    Date of Patent: June 20, 2017
    Assignee: Janssen R & D Ireland
    Inventors: Lieven Elvire Colette Baert, Bruce Albert Malcolm, Roger Paulus Maria Sutmuller
  • POLYINOSINIC-POLYCYTIDYLIC ACID (POLY (I:C)) FORMULATIONS FOR THE TREATMENT OF UPPER RESPIRATORY TRACT INFECTIONS
    Publication number: 20160296551
    Abstract: The present invention concerns a composition comprising micro particles of polyinosinic-polycytidylic acid (Poly (I:C)) and a carrier polymer selected from starch, alginate, blanose or DPPC (dipalmitoylphosphatidylcholine) for use in preventing and/or treating viral infections of the upper respiratory tract or the common cold and a device, preferably a nasal delivery system, comprising said composition for use by a patient in need to prevent and/or treat infections or the common cold.
    Type: Application
    Filed: June 13, 2016
    Publication date: October 13, 2016
    Inventors: Lieven Elvire Colett Baert, Bruce Albert Malcolm, Roger Paulus Maria Sutmuller
  • Polyinosinic-Polycytidylic Acid (Poly (I:C)) Formulations for the Treatment of Upper Respiratory Tract Infections
    Publication number: 20150140042
    Abstract: The present invention concerns a composition comprising micro particles of polyinosinic-polycytidylic acid (Poly (I:C)) and a carrier polymer selected from starch, alginate, blanose or DPPC (dipalmitoylphosphatidylcholine) for use in preventing and/or treating viral infections of the upper respiratory tract or the common cold and a device, preferably a nasal delivery system, comprising said composition for use by a patient in need to prevent and/or treat infections or the common cold.
    Type: Application
    Filed: May 2, 2013
    Publication date: May 21, 2015
    Inventors: Lieven Elvire Colette Baert, Bruce Albert Malcolm, Roger Paulus Maria Sutmuller
  • HIV Membrane Fusion Inhibitors
    Publication number: 20140357577
    Abstract: The present invention concerns an inhibitor of Human Immunodeficiency Virus (HIV) fusion with, or HIV entry in, a host cell comprising at least 24, but preferably 26, contiguous amino acids; the invention also relates to a pharmaceutical composition comprising said amino acids.
    Type: Application
    Filed: December 18, 2012
    Publication date: December 4, 2014
    Inventors: Bruce Albert Malcolm, Johannes Wilhelmus J. Thuring, Christophe Francis Robert Nestor Buyck, Wim Bert Griet Schepens, Maria Aldegonda Jacoba Kriek, Wilhelmus Martinus Maria Schaaper, Jelle Wouter Slootstra, Peter Timmerman