Patents by Inventor Bruce Ames

Bruce Ames has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210274825
    Abstract: The present invention provides nutritional compositions (for example, sensorially acceptable nutritional compositions) that comprise a fruit component, a fiber component, and a micronutrient component. Also provided are methods of making and using the nutritional compositions.
    Type: Application
    Filed: May 25, 2021
    Publication date: September 9, 2021
    Inventors: Bruce Ames, Mark Shigenaga, Michele Mietus Snyder, Joyce McCann, Tara McHugh, Donald A. Olson
  • Publication number: 20210045424
    Abstract: The present invention provides nutritional compositions (for example, sensorially acceptable nutritional compositions) that comprise a fruit component, a fiber component, and a micronutrient component. Also provided are methods of making and using the nutritional compositions.
    Type: Application
    Filed: May 8, 2020
    Publication date: February 18, 2021
    Applicant: The United States of America, as Represented by the Secretary of Agriculture
    Inventors: Bruce Ames, Mark Shigenaga, Michele M. Snyder, Joyce McCann, Tara McHugh, Donald A. Olson
  • Publication number: 20170215466
    Abstract: The present invention provides nutritional compositions (for example, sensorially acceptable nutritional compositions) that comprise a fruit component, a fiber component, and a micronutrient component. Also provided are methods of making and using the nutritional compositions.
    Type: Application
    Filed: January 30, 2017
    Publication date: August 3, 2017
    Inventors: Bruce Ames, Mark Shigenaga, Michele Mietus Snyder, Joyce McCann, Tara McHugh, Donald A. Olson
  • Publication number: 20140308389
    Abstract: The present invention provides nutritional compositions (for example, sensorially acceptable nutritional compositions) that comprise a fruit component, a fiber component, and a micronutrient component. Also provided are methods of making and using the nutritional compositions.
    Type: Application
    Filed: September 30, 2011
    Publication date: October 16, 2014
    Applicants: CHILDREN'S HOSPITAL OAKLAND RESEARCH INSTITUTE
    Inventors: Bruce Ames, Mark Shigenaga, Michele M. Snyder, Joyce McCann, Tara H. McHugh, Danald A. Olson
  • Publication number: 20100323936
    Abstract: A liquid lubricant base oil composition comprising (i) a base stock comprising at least 95% by weight saturated hydrocarbons such as for example a Group II base stock, a Group III base stock and/or a base stock derived from Fischer-Tropsch synthesised, waxy, paraffinic hydrocarbon material and (ii) 0.2 to 30% by weight of an aromatic extract which has a dimethyl sulphoxide extractable polycyclic aromatics content of less than 3 weight % may be made by blending the components together and may be used with one or more additives in a lubricant composition which may be used in applications such as marine engine lubricants.
    Type: Application
    Filed: February 18, 2008
    Publication date: December 23, 2010
    Inventors: Stephen Bruce Ames, John Philip Davies, John Philip Liddy, Kok-Chye Lim
  • Patent number: 7285396
    Abstract: A?-heme peroxidase activity is selectively measured and inhibited, packaged as a pharmaceutical composition with heme biosynthetic cofactors or as an industrial enzyme, and used to oxidize target substrates.
    Type: Grant
    Filed: March 30, 2006
    Date of Patent: October 23, 2007
    Assignee: Children's Hospital & Research Center at Oakland
    Inventors: Hani Alamna, Bruce Ames
  • Publication number: 20070231848
    Abstract: A ?-heme peroxidase activity is selectively measured and inhibited, packaged as a pharmaceutical composition with heme biosynthetic cofactors or as an industrial enzyme, and used to oxidize target substrates.
    Type: Application
    Filed: March 30, 2006
    Publication date: October 4, 2007
    Inventors: Hani Atamna, Bruce Ames
  • Publication number: 20070072927
    Abstract: In a method of treating hypertension in individuals suffering therefrom, the method includes administering to said individuals an effective amount of carnitine and an effective amount of lipoic acid. A method of treating hypertension in individuals suffering therefrom includes administering twice a day a combination of 500 mg carnitine, 200 mg lipoic acid and optionally 100 micrograms of biotin. A method of treating hypertension in individuals with systolic blood pressure above about 135 mmHg includes administering a combination of carnitine, lipoic acid and optionally biotin.
    Type: Application
    Filed: August 10, 2006
    Publication date: March 29, 2007
    Inventors: Joseph Vita, Bruce Ames, Benjamin Treadwell
  • Publication number: 20060188866
    Abstract: Cell senescence is delayed by contacting a cell specifically determined to be in need of delayed cell senescence with an effective amount of a diaminophenothiazine.
    Type: Application
    Filed: February 18, 2005
    Publication date: August 24, 2006
    Inventors: Hani Atamna, Bruce Ames
  • Publication number: 20060078949
    Abstract: The invention is a method for analyzing immature reticulocytes for the presence of micronuclei. The method includes reticulocyte enrichment, fluorescent labeling, micronuclei staining, and analysis using single-laser flow cytometry. The invention also includes kits containing reagents to use in the method.
    Type: Application
    Filed: October 7, 2004
    Publication date: April 13, 2006
    Inventors: Tal Offer, Emily Ho, Bruce Ames, Frans Kuypers
  • Publication number: 20050256088
    Abstract: Pharmaceutical nitrone comprise condensates of an N-hydroxylamine and a physiological aldehyde, providing improved delivery and absorption, enhanced stability and reduced toxicity. Preferred physiological aldehydes are subject to endogenous cellular uptake transport, and include pyridoxal, pyridoxal phosphate, and heme-A. Essentially any physiologically compatible and pharmaceutically active hydroxylamine moiety may be incorporated, such as hydroxylamine moieties of prior pharmaceutical nitrones, and known pharmaceutically active hydroxylamines.
    Type: Application
    Filed: May 11, 2004
    Publication date: November 17, 2005
    Inventors: Bruce Ames, Hani Atamna
  • Publication number: 20050239876
    Abstract: Anti-inflammatory compositions include medicaments comprising predetermined amounts of a phytyl substituted chromanol and a prostaglandin E2 inhibitor, wherein: said medicament is in unit dosage form suitable for pharmaceutical administration; said phytyl substituted chromanol is a gamma-tocopherol, delta-tocopherol, gamma-tocotrienol or delta-tocotrienol; said PGE2 inhibitor is a non-steroidal anti-inflammatory drug or an omega-3 fatty acid, such as docosahexaenoic acid and eicosapentaenoic acid.
    Type: Application
    Filed: June 22, 2005
    Publication date: October 27, 2005
    Inventors: Bruce Ames, Qing Jiang