Patents by Inventor Bruce C. Follows

Bruce C. Follows has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STAT6 INHIBITORS AND USES THEREOF
    Publication number: 20250214977
    Abstract: The present invention provides compounds, compositions, and methods of using the same.
    Type: Application
    Filed: November 11, 2024
    Publication date: July 3, 2025
    Inventors: Huijun Dong, Bin Yang, Bruce C. Follows, Xiao Zhu, Matthew M. Weiss, Xiaozhang Zheng, Xin Huang, Lijing Su, Nello Mainolfi, Thijs Beuming, Xue Fei, Philip Collier, Yi Zhang, Christopher L. Carroll
  • STAT6 INHIBITORS AND USES THEREOF
    Publication number: 20250213586
    Abstract: The present invention provides compounds, compositions, and methods of using the same.
    Type: Application
    Filed: January 2, 2025
    Publication date: July 3, 2025
    Inventors: Huijun Dong, Bin Yang, Bruce C. Follows, Xiao Zhu, Matthew M. Weiss, Xiaozhang Zheng, Xin Huang, Lijing Su, Nello Mainolfi, Thijs Beuming, Xue Fei, Philip Collier, Yi Zhang
  • IRAK DEGRADERS AND USES THEREOF
    Publication number: 20250011325
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: August 9, 2024
    Publication date: January 9, 2025
    Inventors: Nello Mainolfi, Christopher De Savi, Matthew M. Weiss, Xiao Zhu, Xiaozhang Zheng, Bruce C. Follows
  • IRAK degraders and uses thereof
    Patent number: 12091411
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: January 31, 2023
    Date of Patent: September 17, 2024
    Assignee: Kymera Therapeutics, Inc.
    Inventors: Nello Mainolfi, Chris De Savi, Matthew M. Weiss, Xiao Zhu, Xiaozhang Zheng, Bruce C. Follows
  • Inhibitors of protein tyrosine phosphatase 1B
    Patent number: 7521473
    Abstract: Protein tyrosine phosphatases (PTPases) such as PTP1B can play a role in regulating a wide variety of cellular responses such as insulin signaling. Substituted thiophene compounds such as, for example, 2-carboxyl, 3-carboxymethoxy, 5-aryl substituted thiophenes, can inhibit PTP1B and thereby induce greater insulin sensitivity. Accordingly, PTP1B inhibition can provide an alternate treatment for PTPase-mediated disorders such as diabetes.
    Type: Grant
    Filed: February 23, 2005
    Date of Patent: April 21, 2009
    Assignee: Wyeth
    Inventors: Jinbo Lee, Zhao-Kui Wan, Douglas P. Wilson, Bruce C. Follows, Steven J. Kirincich, Michael J. Smith, Jun-Jun Wu, Kenneth W. Foreman, David V. Erbe, Yan-Ling Zhang, Weixin Xu, Steve Y. Tam
  • Inhibitors of Protein Tyrosine Phosphatase 1B
    Publication number: 20090048286
    Abstract: Protein tyrosine phosphatases (PTPases) such as PTP1B can play a role in regulating a wide variety of cellular responses such as insulin signaling. Substituted bicyclic fused-thiophene compounds can inhibit PTP1B and thereby induce greater insulin sensitivity. Accordingly, PTP1B inhibition can provide an alternate treatment for PTPase-mediated disorders such as diabetes.
    Type: Application
    Filed: September 23, 2008
    Publication date: February 19, 2009
    Applicant: Wyeth
    Inventors: Jinbo Lee, Steven J. Kirincich, Michael J. Smith, Douglas P. Wilson, Bruce C. Follows, Zhao-Kui Wan, Diane M. Joseph-McCarthy, David V. Erbe, Yan-Ling Zhang, Weixin Xu, Steve Y. Tam