Abstract: Provided for herein are viral particles comprising a heterologous viral glycoprotein and a targeting moiety, wherein the targeting moiety comprises a polypeptide comprising a formula of T-S1, wherein T is a target binding domain and S1 is a stalk portion. The stalk portion may comprise a variant Fe domain. The stalk portion may comprise a flexible polypeptide domain. The targeting moiety comprising the formula T-S1 may be incorporated into a viral particle to assist with targeting such particles to a specific cell type. Also provided for herein are compositions comprising the same, and methods of using the same.

Abstract: A system and method for performing real-time quality inspection of objects is disclosed. The system and method include a transport to move objects being inspected, allowing the inspection to be performed in-line. At least one optical acquisition unit is provided that captured optical images of the objects being inspected. The captured optical images are matched to CAD models of objects, and the matched CAD model is extracted. A laser with an illumination light beam has a wavelength in the violet or ultraviolet range then conducts scans of the objects, which are formed into three-dimensional point clouds. The point clouds are compared to the extracted CAD models for each object, where CTF are compared to user input or CAD model information and the object is determined to be acceptable or defective based on the extent of deviation between the point cloud and the CAD model.

Abstract: It is well understood in the medical industry that medical disorders can manifest as serious problems for the affected subjects, their families, and society. Today, psychiatrists, neurologists and other physicians treat these disorders with a variety of medications, many of which have significant negative side effects. The teachings provided herein are directed to a novel system and methods for treating certain neurological, psychological, psychiatric and medical disorders by delivering a “magnetic stimulation” to a subject's neural and perineural system using either a static or electromagnetic field to generate a modulated variable power multi-spectral magnetic stimulation on three axis; the modulated stimulation using methods that have predictable, controlled, modifiable, and repeatable characteristics.

Abstract: It is well understood in the medical industry that medical disorders can manifest as serious problems for the affected subjects, their families, and society. Today, psychiatrists, neurologists and other physicians treat these disorders with a variety of medications, many of which have significant negative side effects. The teachings provided herein are directed to a novel system and methods for treating certain neurological, psychological, psychiatric and medical disorders by delivering a “magnetic stimulation” to a subject's neural and perineural system using either a static or electromagnetic field to generate a modulated variable power multi-spectral magnetic stimulation on three axis; the modulated stimulation using methods that have predictable, controlled, modifiable, and repeatable characteristics.

Abstract: It is well understood in the medical industry that medical disorders can manifest as serious problems for the affected subjects, their families, and society. Today, psychiatrists, neurologists and other physicians treat these disorders with a variety of medications, many of which have significant negative side effects. The teachings provided herein are directed to a novel system and methods for treating certain neurological, psychological, psychiatric and medical disorders by delivering a “magnetic stimulation” to a subject's neural and perineural system using either a static or electromagnetic field to generate a modulated variable power multi-spectral magnetic stimulation on three axis; the modulated stimulation using methods that have predictable, controlled, modifiable, and repeatable characteristics.

Abstract: It is well understood in the medical industry that medical disorders can manifest as serious problems for the affected subjects, their families, and society. Today, psychiatrists, neurologists and other physicians treat these disorders with a variety of medications, many of which have significant negative side effects. The teachings provided herein are directed to a novel system and methods for treating certain neurological, psychological, psychiatric and medical disorders by delivering a “magnetic stimulation” to a subject's neural and perineural system using either a static or electromagnetic field to generate a modulated variable power multi-spectral magnetic stimulation on three axis; the modulated stimulation using methods that have predictable, controlled, modifiable, and repeatable characteristics.

Abstract: An intravaginal urinary incontinence device has an insertion end and an opposed withdrawal end. The device has a resilient frame including a working portion disposed proximate the withdrawal end and an anchoring portion disposed proximate the insertion end. The working portion has a resilient structure having a plurality of connected elongate elements arranged and configured to define opposed working surfaces for providing support to an associated urinary system. The anchoring portion extends beyond the working portion and has a plurality of connected elongate elements arranged and configured to expand laterally within a user's vagina. The elongate elements are formed of a high modulus polymer having an elongation at yield of at least 3% and an elastic modulus of at least 2 Gpa.

Abstract: An intravaginal urinary incontinence device has an insertion end and an opposed withdrawal end. The device has a resilient frame including a working portion disposed proximate the withdrawal end and an anchoring portion disposed proximate the insertion end. The working portion has a resilient structure having a plurality of connected elongate elements for providing support to an associated urinary system. The anchoring portion has a plurality of connected elongate elements arranged to expand laterally within a user's vagina. The elongate elements are formed of a high modulus polymer having an elastic modulus of at least 2 or 3 GPa. Additionally, the polymer may have an Initial Stress @ 3% Strain of at least about 30 MPa, an elongation at yield of at least 3%, a Stress Ratio of at least about 0.5, and/or an Aged Stress (t=50 hrs @ 40° C.) @ 3% Strain is greater than about 35 MPa.

Abstract: A multilayered apertured film wrapping element for an absorbent article is disclosed. At least one outer layer of the fluid-impervious plastic material has a continuous phase of a thermoplastic polymeric component and an immiscible, dispersed phase of a thermoplastic polymeric component having a lower melting point. The wrapping element is useful in applications involving heat sealing and similar thermal processes in absorbent articles, such as sanitary napkins, diapers, bandages, tampons, and the like.

Abstract: This invention relates to a novel composition for use in dental flosses or tapes. More particularly, it relates to novel compositions containing a base polymer, a block copolymer and a nonmigrating compatibilizer or plasticizer that, in combination in a blend, result in a floss or dental tape having good breaking strength, elongation, tenacity, nick resistance and gentleness to the gums.

Abstract: A multilayered apertured film wrapping element for an absorbent article is disclosed. At least one outer layer of the fluid-impervious plastic material has a continuous phase of a thermoplastic polymeric component and an immiscible, dispersed phase of a thermoplastic polymeric component having a lower melting point. The wrapping element is useful in applications involving heat sealing and similar thermal processes in absorbent articles, such as sanitary napkins, diapers, bandages, tampons, and the like.

Abstract: This invention relates to a novel composition for use in dental flosses or tapes. More particularly, it relates to novel compositions containing a base polymer, a block copolymer and a nonmigrating compatibilizer or plasticizer that, in combination in a blend, result in a floss or dental tape having good breaking strength, elongation, tenacity, nick resistance and gentleness to the gums.

Abstract: This invention relates to a novel composition for use in dental flosses or tapes. More particularly, it relates to novel compositions containing a base polymer, a block copolymer and a nonmigrating compatibilizer or plasticizer that, in combination in a blend, result in a floss or dental tape having good breaking strength, elongation, tenacity, nick resistance and gentleness to the gums.

Abstract: A nasal dilator that prevents the outer wall tissue of the nasal passages of the nose from drawing in during breathing comprises a truss member. The truss member includes a flexible strip of material having a first end region, a second end region and an intermediate segment. The first and second end regions are adapted to engage the outer wall tissue of first and second nasal passages of the nose. The intermediate segment is configured to traverse a portion of a nose located between the first and second nasal passages. The truss member further includes first and second resilient bands secured to the strip of material adjacent opposite edges of the intermediate segment. The resiliency of the first and second resilient bands acts to stabilize the outer wall tissue and thereby prevents the outer wall tissue of the first and second nasal passages from drawing in during breathing.

Abstract: A fluid delivery system and a propellant therefor. The propellant comprises a mixture of a plurality of substances, the precise by-weight or by-molar combination of which is used to set the propellant pressure within a desirable pressure range. At least one of the plurality of propellant substances is a relatively higher vapor pressure fluid; and at least one of the plurality of propellant substances is a relatively lower vapor pressure fluid.

Abstract: A dental floss formed from a single hollow monofilament in the shape of a flattened tube. The monofilament is formed of a blend that includes a base polymer, a block copolymer and a compatibilizer.

Abstract: A method of fabricating a stimulation electrode for use on an implantable lead, the lead and electrode so fabricated and a method of their use. The electrode is made by coating a conductive electrode member with a coating of a high surface area coating having micron or sub-micron surface features and after coating, plasma cleaning the electrode member. The electrode is coupled to an insulated conductor of an implantable lead and is employed to stimulate body tissue. The high surface area coating may be platinum black, ruthenium oxide, another metal oxide, a metal nitride or the like. Steroid may be applied to the electrode member after coating.

Abstract: This invention relates to a novel composition for use in dental flosses or tapes. More particularly, it relates to novel compositions containing a base polymer, a block copolymer and a nonmigrating compatibilizer or plasticizer that, in combination in a blend, result in a floss or dental tape having good breaking strength, elongation, tenacity, nick resistance and gentleness to the gums.

Abstract: A chain link comprising a shank portion connected to a pair of eye portions at each end of the shank so as to form a dog-bone shape with eyelets at the ends. The eyelets are formed by a Y-shaped root section that is connected to a half-torus-shaped hat section. The cross-section profile of the shank portion is round, square, or, alternatively, an I-beam shape. The eye portions include an inner portion having an arcuate inner surface and an outer portion being substantially rectangular in cross-section. The chain link is preferably made of a high-strength alloy steel and is especially well-suited for use in dragline hoist chains.

Abstract: A quench system for cooling hot flue gases from combustion systems is disclosed. The quench system includes a venturi mounted in a quench vessel. The water level in the quench vessel may be raised or lowered in accordance with the flow rate of the gases to be quenched. When the pressure drop across the venturi is insufficient to achieve the desired cooling to adiabatic saturation temperature, the water level is increased so that the downcomer connected to the venturi is submerged and the additional pressure drop further cools the flue gases.