Patents by Inventor Bruce C. Trapnell

Bruce C. Trapnell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell therapy with lentiviral transduced CSF2RA transgene in the treatment of hereditary pulmonary alveolar proteinosis
    Patent number: 12043844
    Abstract: The disclosure provides compositions and methods for cell therapy of hPAP in humans using gene corrected and in vitro differentiated patient autologous macrophage cells. The disclosure also provides compositions in the form of a cell product and related compositions and methods for making the cell product and for direct pulmonary transplantation of same.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: July 23, 2024
    Assignees: Medizinische Hochschule Hannover
    Inventors: Bruce C. Trapnell, Takuji Suzuki, Thomas Moritz, Nico Lachmann, Axel Schambach
  • CELL THERAPY WITH LENTIVIRAL TRANSDUCED CSF2RA TRANSGENE IN THE TREATMENT OF HEREDITARY PULMONARY ALVEOLAR PROTEINOSIS
    Publication number: 20200199623
    Abstract: The disclosure provides compositions and methods for cell therapy of hPAP in humans using gene corrected and in vitro differentiated patient autologous macrophage cells. The disclosure also provides compositions in the form of a cell product and related compositions and methods for making the cell product and for direct pulmonary transplantation of same.
    Type: Application
    Filed: May 16, 2018
    Publication date: June 25, 2020
    Inventors: Bruce C Trapnell, Takuji Suzuki, Thomas Moritz, Nico Lachmann, Axel Schambach
  • Methods and compositions for determining and treating relapse in inflammatory bowel disease
    Patent number: 9995752
    Abstract: Described are methods and compositions for evaluating the relapse risk n subjects having an inflammatory bowel disease (IBD). Some embodiments include selecting a treatment for an evaluated IBD relapse risk in a subject.
    Type: Grant
    Filed: May 13, 2014
    Date of Patent: June 12, 2018
    Assignees: Children's Hospital Medical Center, Westfaelische Wilhelms-Universitaet Muenster
    Inventors: Lee A. Denson, Bruce C. Trapnell, Jan Däbritz
  • METHODS AND COMPOSITIONS FOR DETERMINING RELAPSE IN INFLAMMATORY BOWEL DISEASE
    Publication number: 20160084846
    Abstract: Described are methods and compositions for evaluating the relapse risk n subjects having an inflammatory bowel disease (IBD). Some embodiments include selecting a treatment for an evaluated IBD relapse risk in a subject.
    Type: Application
    Filed: May 13, 2014
    Publication date: March 24, 2016
    Inventors: Lee A. Denson, Bruce C. Trapnell, Jan Däbritz