Abstract: The present invention provides 75 kD transmembrane neurotrophin receptor (p75NTR) antagonists and their use in prevention and treatment of loss of function, and adverse remodeling, in cardiac tissues subject to acute or chronic hemodynamic stress. Uses of the antagonists with or without additional cardiotropic agents for improving contractility and for treatment of congestive heart failure are also provided.

Abstract: An apparatus for communicating with a downhole tool includes a sensor body including at least two electrodes electrically insulated from one another and an external control device configured to engage the two electrodes. Detection circuitry connected to the two electrodes is configured to monitor an electrical status across the two electrodes, through the external control device, and upon detecting a change in electrical status that matches a predefined pattern, communicate a command to power management circuitry to alter a power status of the downhole tool.

Abstract: The present invention provides 75 kD transmembrane neurotrophin receptor (p75NTR) antagonists and their use in prevention and treatment of loss of function, and adverse remodeling, in cardiac tissues subject to acute or chronic hemodynamic stress. Uses of the antagonists with or without additional cardiotropic agents for improving contractility and for treatment of congestive heart failure are also provided.

Abstract: A bottom hole assembly attached to a drillstring includes a main body including multiple electrical insulator sections along a length thereof, each of the electrical insulator sections configured to have a voltage difference generated there across, wherein a transmitting electrical insulator section having a voltage difference generated there across is configured to remain open, and wherein all remaining electrical insulator sections are configured to be electrically shorted there across.

Abstract: An apparatus for communicating with a downhole tool includes a sensor body including at least two electrodes electrically insulated from one another and an external control device configured to engage the two electrodes. Detection circuitry connected to the two electrodes is configured to monitor an electrical status across the two electrodes, through the external control device, and upon detecting a change in electrical status that matches a predefined pattern, communicate a command to power management circuitry to alter a power status of the downhole tool.

Abstract: A bottom hole assembly attached to a drillstring includes a main body including multiple electrical insulator sections along a length thereof, each of the electrical insulator sections configured to have a voltage difference generated there across, wherein a transmitting electrical insulator section having a voltage difference generated there across is configured to remain open, and wherein all remaining electrical insulator sections are configured to be electrically shorted there across.

Abstract: Change control in a software release stream is managed by a computer implemented Request To Integrate (RTI) system, including at least one user unit having an input unit and a display. A server unit which is connected to the user unit(s) creates and stores RTI files representing requests to integrate changes into the software release stream, and enables a selected RTI file to be displayed on the display unit under control of the input unit. The server unit includes a database in which the RTI files are stored under the Source Code Control System (SCCS), and a search engine for searching the database and displaying selected RTI files and their histories. The RTI files are in World Wide Web (WWW) HyperText Markup Language (HTML) text format, and are accessible through a WWW browser in the user unit(s) and a cooperating WWW server in the server unit. The server unit stores and executes a program including a WWW home page, and developer, evaluator and gatekeeper pages which are accessible through the home page.