Patents by Inventor Bruce Cherksey

Bruce Cherksey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for gene transfer to the central nervous system
    Patent number: 6565845
    Abstract: The present invention relates to a method for implanting producer cells into the mammalian brain. The producer cells are engineered with a retroviral based recombinant vector encoding a tumorcidal factor or susceptibility factor that confers on tumor cells sensitivity to chemotherapeutic or radiotherapeutic agents. Prior to transplantation into the mammalian brain, the producer cells are first cultured in vitro on a support matrix to increase the long-term viability of the transplanted cells and to provide long-term functional benefit.
    Type: Grant
    Filed: December 4, 2000
    Date of Patent: May 20, 2003
    Assignees: Titan Pharmaceuticals, Inc., New York University Medical Center
    Inventors: Bruce Cherksey, Louis R. Bucalo
  • Method for gene transfer to the central nervous system
    Publication number: 20010003585
    Abstract: The present invention relates to a method for implanting producer cells into the mammalian brain. The producer cells are engineered with a retroviral based recombinant vector encoding a tumorcidal factor or susceptibility factor that confers on tumor cells sensitivity to chemotherapeutic or radiotherapeutic agents. Prior to transplantation into the mammalian brain, the producer cells are first cultured in vitro on a support matrix to increase the long-term viability of the transplanted cells and to provide long-term functional benefit.
    Type: Application
    Filed: December 4, 2000
    Publication date: June 14, 2001
    Inventors: Bruce Cherksey, Louis R. Bucalo
  • Method for gene transfer to the central nervous system
    Patent number: 6210664
    Abstract: The present invention relates to a method for implanting producer cells into the mammalian brain. The producer cells are engineered with a retroviral based recombinant vector encoding a tumorcidal factor or susceptibility factor that confers on tumor cells sensitivity to chemotherapeutic or radiotherapeutic agents. Prior to transplantation into the mammalian brain, the producer cells are first cultured in vitro on a support matrix to increase the long-term viability of the transplanted cells and to provide long-term functional benefit.
    Type: Grant
    Filed: April 8, 1996
    Date of Patent: April 3, 2001
    Assignees: New York University Medical Center, Titan Pharmaceuticals, Inc.
    Inventors: Bruce Cherksey, Louis R. Bucalo
  • Potassium channel activating compounds and methods of use thereof
    Patent number: 5234947
    Abstract: A method for activating potassium channels and for treating hypertension, addiction, asthma, incontinence, and other conditions treatable by potassium channel activators, such as spasms and convulsions, comprising administering a compound having the formula: ##STR1## wherein R is a saturated or unsaturated group having from 1 to 4 carbon atoms which is optionally substituted by lower alkyl, lower alkenyl or lower alkoxy groups; andwherein R' is hydrogen, lower alkyl, lower alkenyl, or aralkyl.
    Type: Grant
    Filed: November 7, 1991
    Date of Patent: August 10, 1993
    Assignee: New York University
    Inventor: Bruce Cherksey