Patents by Inventor Bruce D. Irvine

Bruce D. Irvine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Signal detection techniques for the detection of analytes
    Patent number: 9874542
    Abstract: The invention relates to the use of signal processing methods in order to achieve higher signal to noise ratios, to increase the detection limits of target analytes. These techniques include the monitoring of the output signal at higher harmonic frequencies.
    Type: Grant
    Filed: October 14, 2014
    Date of Patent: January 23, 2018
    Assignee: CLINICAL MICRO SENSORS, INC.
    Inventors: Robert M. Umek, Gary Blackburn, Bruce D. Irvine, Robert Terbrueggen, Changjun Yu, Jost G. Vielmetter
  • SIGNAL DETECTION TECHNIQUES FOR THE DETECTION OF ANALYTES
    Publication number: 20150126391
    Abstract: The invention relates to the use of signal processing methods in order to achieve higher signal to noise ratios, to increase the detection limits of target analytes. These techniques include the monitoring of the output signal at higher harmonic frequencies.
    Type: Application
    Filed: October 14, 2014
    Publication date: May 7, 2015
    Applicant: GenMark Diagnostics Inc.
    Inventors: Robert M. UMEK, Gary Blackburn, Bruce D. Irvine, Robert Terbrueggen, Changjun Yu, Jost G. Vielmetter
  • Sequence determination of nucleic acids using electronic detection
    Patent number: 7935481
    Abstract: The present invention is directed to methods and compositions for the use of self-assembled monolayers to electronically detect nucleic acids, particularly alterations such as nucleotide substitutions (mismatches) and single nucleotide polymorphisms (SNPs).
    Type: Grant
    Filed: July 26, 2000
    Date of Patent: May 3, 2011
    Assignee: Osmetech Technology Inc.
    Inventors: Robert M. Umek, Gary Blackburn, Bruce D. Irvine, Robert H. Terbrueggen, Changjun Yu, Jost G. Vielmetter
  • Binding acceleration techniques for the detection of analytes
    Patent number: 7655129
    Abstract: The invention relates to compositions and methods useful in the acceleration of binding of target analytes to capture ligands on surfaces. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, either directly or indirectly, to allow electronic detection of the ETM.
    Type: Grant
    Filed: April 12, 2004
    Date of Patent: February 2, 2010
    Assignee: Osmetech Technology Inc.
    Inventors: Gary Blackburn, Stephen E. Creager, Scott Fraser, Bruce D. Irvine, Thomas J. Meade, Stephen J. O'Connor, Robert H. Terbrueggen, Jost G. Vielmetter, Thomas W. Welch
  • Printed circuit boards with monolayers and capture ligands
    Patent number: 6761816
    Abstract: The invention relates to compositions and methods useful in the acceleration of binding of target analytes to capture ligands on surfaces. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, either directly or indirectly, to allow electronic detection of the ETM.
    Type: Grant
    Filed: March 8, 2000
    Date of Patent: July 13, 2004
    Assignee: Clinical Micro Systems, Inc.
    Inventors: Gary Blackburn, Stephen E. Creager, Scott Fraser, Bruce D. Irvine, Thomas J. Meade, Stephen D. O'Connor, Robert H. Terbrueggen, Jost G. Vielmetter, Thomas W. Welch
  • Amplification of nucleic acids with electronic detection
    Patent number: 6686150
    Abstract: The invention relates to compositions and methods useful in the detection of nucleic acids using a variety of amplification techniques, including both signal amplification and target amplification. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the nucleic acid, either directly or indirectly, to allow electronic detection of the ETM using an electrode.
    Type: Grant
    Filed: July 20, 2000
    Date of Patent: February 3, 2004
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Gary Blackburn, Bruce D. Irvine, Jon Faiz Kayyem, Edward Lewis Sheldon, III, Robert H. Terbrueggen
  • HIV probes for use in solution phase sandwich hybridization assays
    Patent number: 6300056
    Abstract: Novel DNA probe sequences for detection of HIV in a sample in a solution phase sandwich hybridization assay are described. Amplified nucleic acid hybridization assays using the probes are exemplified.
    Type: Grant
    Filed: December 17, 1993
    Date of Patent: October 9, 2001
    Assignee: Chiron Corporation
    Inventors: Bruce D. Irvine, Janice A. Kolberg, Michael S. Urdea
  • Binding acceleration techniques for the detection of analytes
    Patent number: 6264825
    Abstract: The invention relates to compositions and methods useful in the acceleration of binding of target analytes to capture ligands on surfaces. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, either directly or indirectly, to allow electronic detection of the ETM.
    Type: Grant
    Filed: June 23, 1999
    Date of Patent: July 24, 2001
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Gary Blackburn, Stephen E. Creager, Scott Fraser, Bruce D. Irvine, Thomas J. Meade, Stephen D. O'Connor, Robert H. Terbrueggen, Jost G. Vielmetter, Thomas W. Welch
  • Hepatitis C virus isolate polypeptides
    Patent number: 5856437
    Abstract: Two new isolates of the Hepatitis C virus (HCV), J1 and J7, are disclosed. These new isolates comprise nucleotide and amino acid sequences which are distinct from the prototype HCV isolate, HCV1. Thus, J1 and J7 provide new polynucleotides and polypeptides for use, inter alia, in diagnostics, recombinant protein production and vaccine development.
    Type: Grant
    Filed: November 3, 1994
    Date of Patent: January 5, 1999
    Assignees: Chiron Corporation, The Director General of the National Institute of Health of Japan
    Inventors: Tatsuo Miyamura, Izumi Saito, Michael Houghton, Amy J. Weiner, Jang Han, Janice A. Kolberg, Tai-An Cha, Bruce D. Irvine
  • HBV capture and amplifiers probes for use in solution phase sandwich hybridization assays
    Patent number: 5736316
    Abstract: Novel DNA probe sequences for detection of HBV in a sample in a solution phase sandwich hybridization assay are described. Amplified nucleic acid hybridization assays using the probes are exemplified.
    Type: Grant
    Filed: January 24, 1994
    Date of Patent: April 7, 1998
    Assignee: Chiron Corporation
    Inventors: Bruce D. Irvine, Janice A. Kolberg, Joyce A. Running, Michael S. Urdea
  • Hepatitis C virus isolates
    Patent number: 5372928
    Abstract: Two new isolates of the Hepatitis C virus (HCV), J1 and J7, are disclosed. These new isolates comprise nucleotide and amino acid sequences which are distinct from the prototype HCV isolate, HCV1. Thus, J1 and J7 provide new polynucleotides and polypeptides for use, inter alia, in diagnostics, recombinant protein production and vaccine development.
    Type: Grant
    Filed: February 24, 1994
    Date of Patent: December 13, 1994
    Assignees: Chiron Corporation, The Director General of the National Institute of Health of Japan
    Inventors: Tatsuo Miyamura, Izumi Saito, Michael Houghton, Amy J. Weiner, Jang Han, Janice A. Kolberg, Tai-An Cha, Bruce D. Irvine
  • Fluid sequestration apparatus
    Patent number: D886320
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: June 2, 2020
    Assignee: WAVESENSE, INC.
    Inventors: Timothy M. Bruemmer, Bruce D. Irvine, Christopher Feistel
  • Annular magnet housing
    Patent number: D890362
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: July 14, 2020
    Assignee: WAVESENSE, INC.
    Inventors: Timothy M. Bruemmer, Bruce D. Irvine, Christopher Feistel, Pawel Juraszek