Patents by Inventor Bruce Darryl Hirsche

Bruce Darryl Hirsche has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIC HEPATITIS C VIRUS ANTIGENS FOR ELICITING AN IMMUNE RESPONSE
    Publication number: 20110223185
    Abstract: Disclosed herein are chimeric antigens, comprising an hepatitis C virus (HCV) antigen and a Fc fragment of an immunoglobulin for eliciting an immune response against said antigen. The immune response is enhanced by presenting the host immune system with an immune response domain (HCV antigen from HVC core, envelope, or non-structural protein fragments) and a target binding domain (an Fc fragment). By virtue of the target binding domain, antigen presenting cells internalize and process the chimeric antigens for antigen presentation, thereby eliciting both a humoral and cellular immune response.
    Type: Application
    Filed: May 18, 2011
    Publication date: September 15, 2011
    Inventors: Rajan George, Lorne Tyrrell, Antoine Noujaim, Dakun Wang, Allan Ma, Bruce Motyka, Bruce Darryl Hirsche
  • Chimeric Hepatitis C Virus Antigens For Eliciting an Immune Response
    Publication number: 20090238822
    Abstract: Disclosed herein are chimeric antigens, comprising an hepatitis C virus (HCV) antigen and a Fc fragment of an immunoglobulin for eliciting an immune response against said antigen. The immune response is enhanced by presenting the host immune system with an immune response domain (HCV antigen from HCV core, envelope, or non-structural protein fragments) and a target binding domain (an Fc fragment). By virtue of the target binding domain, antigen presenting cells internalize and process the chimeric antigens for antigen presentation, thereby eliciting both a humoral and cellular immune response.
    Type: Application
    Filed: October 13, 2006
    Publication date: September 24, 2009
    Applicant: VIREXX MEDICAL CORP.
    Inventors: Rajan George, Lorne Tyrrell, Antoine A. Noujaim, Bruce Darryl Hirsche, Dakun Wang, Allan Ma, Bruce Motyka
  • Reagents and methods for inducing an immune response to prostate specific antigen
    Publication number: 20090220493
    Abstract: The invention is an apparatus and method for the treatment of prostate cancer, and involves administering an antibody that specifically binds with prostate antigen.
    Type: Application
    Filed: October 31, 2007
    Publication date: September 3, 2009
    Applicant: AltaRex Medical Corp.
    Inventors: Beatrice Leveugle, Ragupathy Madiyalakan, Antoine A. Noujaim, Birgit C. Schultes, Bruce Darryl Hirsche
  • Method for diagnosing efficacy of xenotypic antibody therapy
    Publication number: 20090202560
    Abstract: The invention concerns methods and compositions for intiating and/or enhancing an immune response by contacting a binding reagent with a soluble antigen, wherein the binding reagent-antigen pair generates an immune response to the antigen.
    Type: Application
    Filed: October 31, 2007
    Publication date: August 13, 2009
    Applicant: AltaRex Medical Corp.
    Inventors: Ragupathy Madiyalakan, Antoine A. Noujaim, Richard P. Baum, Bruce Darryl Hirsche