Patents by Inventor Bruce Devens

Bruce Devens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYPEPTIDE INHIBITORS OF VLA4
    Publication number: 20120135912
    Abstract: The invention provides novel 2D-VCAM-1 variant polypeptides and conjugates thereof that bind human VLA4. The invention also provides related polynucleotides, compositions, vectors, host cells, and methods.
    Type: Application
    Filed: May 10, 2011
    Publication date: May 31, 2012
    Applicant: PERSEID THERAPEUTICS LLC
    Inventors: MADAN M. PAIDHUNGAT, AMULYA NANISETTI, THOMAS BOUQUIN, KIM VILBOUR ANDERSEN, STEVEN J. CHAPIN, CLAUS KREBBER, RONG A. FAN, DANIEL MALASHOCK, AMY BRIDEAU-ANDERSEN, ERIK KARRER, BRUCE DEVENS, STEVEN H. BASS
  • COMPOSITIONS AND METHODS FOR MODULATING BONE MASS
    Publication number: 20090202572
    Abstract: The instant invention relates to compositions and methods for treating or preventing bone diseases. In certain aspects, the invention provides compositions comprising a ?-adrenergic antagonist or agonist associated to a bone-targeted molecule, as well as methods of modulating bone mass and/or growth in a mammal by administering a composition of the present invention. In other aspects, the invention provides methods of modulating bone mass and/or growth in a mammal by administering a composition comprising a ?2-selective antagonist or agonist.
    Type: Application
    Filed: May 13, 2006
    Publication date: August 13, 2009
    Inventors: Gerard Karsenty, Bruce Devens
  • Immunomodulation with novel pharmaceutical compositions
    Publication number: 20060167054
    Abstract: The synthesis and use of a novel class of tumor necrosis factor (TNF?) inhibitors and immunomodulators are provided. Examples are those having the structures: wherein a, b and c are integers from 0 to 12, X equals NH or CHNH2, R1 and R2 each is a hydrogen or a C1 to C20 aliphatic; aliphatic amine; an alicyclic; aromatic; heterocycle; and halogenated forms thereof; and wherein, a, b and c are integers from 0 to 12; R1, R2, R3, and R4 each is a hydrogen or a C1 to C20; aliphatic amine; an alicyclic; aromatic; a heterocycle; and halogenated forms thereof.
    Type: Application
    Filed: July 1, 2005
    Publication date: July 27, 2006
    Applicant: MediQuest Therapeutics, Inc.
    Inventors: Mark Burns, Maralee McVean, Kevin Kennedy, Arthur Yeung, Bruce Devens