Patents by Inventor Bruce E. Maryanoef

Bruce E. Maryanoef has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptidyl heterocyclic ketones useful as tryptase inhibitors
    Patent number: 7132418
    Abstract: The present invention relates to a series of peptidyl heterocyclic ketones which are inflammatory cell serine protease inhibitors and their compositions and methods for the prevention and treatment of a variety of immunomediated inflammatory disorders. More particularly, these compounds are potent and selective inhibitors of tryptase and are therefore effective for the prevention and treatment of inflammatory diseases associated with the respiratory tract, such as asthma and allergic rhinitis.
    Type: Grant
    Filed: July 25, 2002
    Date of Patent: November 7, 2006
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Michael J. Costanzo, Bruce E. Maryanoef, Stephen C. Yabut
  • Peptidyl heterocyclic ketones useful as tryptase inhibitors
    Publication number: 20030008829
    Abstract: The present invention relates to a series of peptidyl heterocyclic ketones which are inflammatory cell serine protease inhibitors and their compositions and methods for the prevention and treatment of a variety of immunomediated inflammatory disorders. More particularly, these compounds are potent and selective inhibitors of tryptase and are therefore effective for the prevention and treatment of inflammatory diseases associated with the respiratory tract, such as asthma and allergic rhinitis.
    Type: Application
    Filed: July 25, 2002
    Publication date: January 9, 2003
    Inventors: Michael J. Costanzo, Bruce E. Maryanoef, Stephen C. Yabut