Patents by Inventor Bruce E. Watkins

Bruce E. Watkins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for immunodiagnostic detection of dioxins at low concentrations
    Patent number: 5429925
    Abstract: A method is described for the use of monoclonal antibodies in a sensitive immunoassay for halogenated dioxins and dibenzofurans in industrial samples which contain impurities. Appropriate sample preparation and selective enzyme amplification of the immunoassay sensitivity permits detection of dioxin contaminants in industrial or environmental samples at concentrations in the range of a few parts per trillion.
    Type: Grant
    Filed: October 26, 1992
    Date of Patent: July 4, 1995
    Assignee: The Regents of the University of California
    Inventors: Martin Vanderlaan, Larry H. Stanker, Bruce E. Watkins, Peter Petrovic, Siegbert Gorbach
  • Monoclonal antibodies to cyclodiene insecticides and method for detecting the same
    Patent number: 5334528
    Abstract: Methods are described for making specific monoclonal antibodies useful for detection of cyclodienes in foods and environmental samples. Monoclonal antibodies specifically reactive with cyclodienes can detect accumulated pesticides in food, tissue or environmental samples. Extraction and preparation of organic samples for immunoassay in a polar-nonpolar reaction medium permits detection of halogenated organic ring structures at concentrations in samples.
    Type: Grant
    Filed: October 30, 1989
    Date of Patent: August 2, 1994
    Assignee: The Regents of the University of California
    Inventors: Larry H. Stanker, Martin Vanderlaan, Bruce E. Watkins
  • Monoclonal antibodies to synthetic pyrethroids and method for detecting the same
    Patent number: 5108900
    Abstract: Methods are described for making specific monoclonal antibodies which may be used in a sensitive immunoassay for detection of synthetic pyrethroids in foods and environmental samples. Appropriate sample preparation and enzyme amplification of the immunoassay for this widely-used class of pesticides permits detection at low levels in laboratory and field tested samples.
    Type: Grant
    Filed: March 6, 1989
    Date of Patent: April 28, 1992
    Assignee: Regents of the University of California
    Inventors: Larry H. Stanker, Martin Vanderlaan, Bruce E. Watkins, Jeanette M. Van Emon, Carolyn L. Bigbee
  • Monoclonal antibodies for the separate detection of halodeoxyuridines and method for their use
    Patent number: 5053336
    Abstract: Monoclonal antibodies are described which have specific affinities for halogenated nucleoside analogs and are preferentially selective for one particular halogen. Such antibodies, when incorporated into immunochemical reagents, may be used to identify and independently quantify the cell division character of more than one population or subpopulation in flow cytometric measurements. Independent assessment of division activity in cell sub-populations facilitates selection of appropriate time and dose for administration of anti-proliferative agents. The hybridomas which secrete halogen selective antibodies and the method of making them are described.
    Type: Grant
    Filed: July 17, 1989
    Date of Patent: October 1, 1991
    Assignee: Regents of the University of California
    Inventors: Martin Vanderlaan, Bruce E. Watkins, Larry H. Stanker
  • Monoclonal antibodies and method for detecting dioxins and dibenzofurans
    Patent number: 4798807
    Abstract: Compositions of matter are described which include five monoclonal antibodies that react with dioxins and dibenzofurans, and the five hybridomas that produce these monoclonal antibodies. In addition, a method for the use of these antibodies in a sensitive immunoassay for dioxins and dibenzofurans is given, which permits detection of these pollutants in samples at concentrations in the range of a few parts per billion.
    Type: Grant
    Filed: June 24, 1986
    Date of Patent: January 17, 1989
    Assignee: The Regents of the University of California
    Inventors: Martin Vanderlaan, Larry H. Stanker, Bruce E. Watkins, Nina R. Bailey