Patents by Inventor Bruce Elliot Tabashnik

Bruce Elliot Tabashnik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Suppression of resistance in insects to bacillus thuringiensis cry toxins that do not require the cadherin receptor
    Patent number: 10704059
    Abstract: The present invention provides a method to obtain DNA constructs that encode 3-domain Cry toxins (also called Cry toxins, Bt toxins, or ?-endotoxins) lacking helix ?-1. These DNA constructs have been modified to encode proteins that kill insects that are resistant to the corresponding unmodified Cry toxins. The DNA constructs encoding the Modified 3-Domain Cry Toxins and the encoded Modified 3-Domain Cry Toxins are provided together with the molecular vectors and the host cell comprising said constructs and the recombinant methods to produce the Modified 3-Domain Cry Toxins. Additionally, compositions comprising the Modified 3-Domain Cry Toxins are disclosed. The resistance of the insects to unmodified Cry toxins is due to reduced toxin binding to the insects' midgut receptors. The invention further provides methods to overcome resistance in crop pests.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: July 7, 2020
    Inventors: Liliana Pardo-Lopez, Bruce Elliot Tabashnik, Mario Soberon-Chavez, Maria Alejandra Bravo De La Parra
  • SUPPRESSION OF RESISTANCE IN INSECTS TO BACILLUS THURINGIENSIS CRY TOXINS THAT DO NOT REQUIRE THE CADHERIN RECEPTOR
    Publication number: 20180282758
    Abstract: The present invention provides a method to obtain DNA constructs that encode 3-domain Cry toxins (also called Cry toxins, Bt toxins, or ?-endotoxins) lacking helix ?-1. These DNA constructs have been modified to encode proteins that kill insects that are resistant to the corresponding unmodified Cry toxins. The DNA constructs encoding the Modified 3-Domain Cry Toxins and the encoded Modified 3-Domain Cry Toxins are provided together with the molecular vectors and the host cell comprising said constructs and the recombinant methods to produce the Modified 3-Domain Cry Toxins. Additionally, compositions comprising the Modified 3-Domain Cry Toxins are disclosed. The resistance of the insects to unmodified Cry toxins is due to reduced toxin binding to the insects' midgut receptors. The invention further provides methods to overcome resistance in crop pests.
    Type: Application
    Filed: April 10, 2018
    Publication date: October 4, 2018
    Applicants: UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO, ARIZONA BOARD OF REGENTS ON BEHALF OF UNIVERSITY OF ARIZONA
    Inventors: LILIANA PARDO-LOPEZ, BRUCE ELLIOT TABASHNIK, MARIO SOBERON-CHAVEZ, MARIA ALEJANDRA BRAVO DE LA PARRA
  • Suppression of Resistance in Insects to Bacillus Thuringiensis Cry Toxins, Using Toxins that do not Require the Cadherin Receptor
    Publication number: 20100186123
    Abstract: The present invention provides a method to obtain DNA constructs that encode 3-domain Cry toxins (also called Cry toxins, Bt toxins, or ?-endotoxins) lacking helix ?-1. These DNA constructs have been modified to encode proteins that kill insects that are resistant to the corresponding unmodified Cry toxins. The DNA constructs encoding the Modified 3-Domain Cry Toxins and the encoded Modified 3-Domain Cry Toxins are provided together with the molecular vectors and the host cell comprising said constructs and the recombinant methods to produce the Modified 3-Domain Cry Toxins. Additionally, compositions comprising the Modified 3-Domain Cry Toxins are disclosed. The resistance of the insects to unmodified Cry toxins is due to reduced toxin binding to the insects' midgut receptors. The invention further provides methods to overcome resistance in crop pests.
    Type: Application
    Filed: June 8, 2007
    Publication date: July 22, 2010
    Inventors: Liliana Pardo-Lopez, Bruce Elliot Tabashnik, Mario Soberon-Chavez, Maria Alejandra Bravo-De La Parra