Abstract: This invention relates to an oral dosage form containing between 1 mg and 100 mg of memantine, wherein said dosage form does not contain 10 mg of memantine or 20 mg of memantine, and wherein said dosage form is not prepared by the patient or a person administering the drug to the patient who divides the dosage form containing a larger dose of memantine. Other aspects of this invention relate to pharmaceutical products comprising said dosage forms and methods of administering memantine and treating disease with said dosage form.

Abstract: A capsule system for oral delivery of an active agent having low aqueous solubility generally includes, in combination with the active agent, a vehicle for preventing initial active agent dissolution within the gastrointestinal tract and an emulsifier for promoting self-emulsification of the active agent and vehicle in the gastrointestinal tract. A capsule shell is provided for encapsulating the active agent, vehicle and emulsifier with the shell being formulated to open upon ingestion into the gastrointestinal tract and release the active agent and vehicle.

Abstract: A capsule system for oral delivery of an active agent having low aqueous solubility generally includes, in combination with the active agent, a vehicle for preventing initial active agent dissolution within the gastrointestinal tract and an emulsifier for promoting self-emulsification of the active agent and vehicle in the gastrointestinal tract. A capsule shell is provided for encapsulating the active agent, vehicle and emulsifier with the shell being formulated to open upon ingestion into the gastrointestinal tract and release the active agent and vehicle.

Abstract: A method for enabling deliver of an active agent is provided which includes the preparation of doses of the active agent distributing educational materials and guidelines for counseling patients with regard to what the patients need to know and what the patients must do in order to both avoid adverse side effects while taking the dose and to receive prescriptions for the doses.

Abstract: A capsule system for oral delivery of an active agent having low aqueous solubility generally includes, in combination with the active agent, a vehicle for preventing initial active agent dissolution within the gastrointestinal tract and an emulsifier for promoting self-emulsification of the active agent and vehicle in the gastrointestinal tract. A capsule shell is provided for encapsulating the active agent, vehicle and emulsifier with the shell being formulated to open upon ingestion into the gastrointestinal tract and release the active agent and vehicle.

Abstract: A capsule system for oral delivery of an active agent having low aqueous solubility generally includes, in combination with the active agent, a vehicle for preventing initial active agent dissolution within the gastrointestinal tract and an emulsifier for promoting self-emulsification of the active agent and vehicle in the gastrointestinal tract. A capsule shell is provided for encapsulating the active agent, vehicle and emulsifier with the shell being formulated to open upon ingestion into the gastrointestinal tract and release the active agent and vehicle.

Abstract: A packaged pharmaceutical product having extended shelf life includes a pharmaceutical preparation and a dispensing container. The container has a hollow body, having an open end therein, and is formed from a blend of low density polyethylene, having high permeability of label-related extractables, and a polypropylene, having low permeability of label-related extractables. A body wall thickness enables both drop-by-drop dispensing of the pharmaceutical preparation by manual squeezing of the body, and, in combination with the blend of polymers, prevents significant ingress of label-related extractables through the body wall upon storage of the container with the body filled with the pharmaceutical preparation. A dropper tip fixed to the body open end is provided for forming droplets of pharmaceutical preparation upon manual squeezing of the body.

Abstract: A packaged pharmaceutical product having extended shelf life includes a pharmaceutical preparation comprising chlorobutanol and a dispensing container. The container has a hollow body, having an open end therein and is formed from a blend of low density polyethylene, having high chlorobutanol permeability, and a polypropylene, having low chlorobutanol permeability. A body wall thickness, enables both drop-by-drop dispensing of the pharmaceutical preparation by manual squeezing of the body, and, in combination with the blend of polymers, preventing significant loss of chlorobutanol through the body wall upon storage of the container with the body filled with the pharmaceutical preparation. A dropper tip fixed to the body open end is provided for forming droplets of pharmaceutical preparation upon manual squeezing of the body.