Abstract: Radionuclide emission imaging is improved by correcting emission-transmission data for attenuation along calculated path lengths and through calculated basis material. X-ray transmission data are used to develop an attenuation map through an object which is then used in reconstructing an image based on emission data, Radiation detection circuitry is provided which has different operating modes in detecting the x-ray and emission photons passing through the object. An iterative process is used to reconstruct the radionuclide distribution using the radionuclide projection data and the attenuation map based on physical characteristics of the object being imaged. Subsets of the complete radionuclide projection data are used to reconstruct image subsets of the radionuclide distribution. The image subsets can be generated concurrently with the acquisition of the radionuclide projection data or following acquisition of all data.

Abstract: Radionuclide emission imaging is improved by correcting emission transmission data for attenuation along calculated path lengths and through calculated basis material. Single or dual energy projector data can be simultaneously obtained with radionuclide emission data to improve localization of radionuclide uptake. Dual energy x-ray projection techniques are used to calculate the path lengths and basis material (bone, tissue, fat). The radionuclide emission data and the transmitted x-ray data are simultaneously obtained using an energy selective photon detector whereby problems of misregistration are overcome. The dual-energy x-ray projection data are utilized to determine material-specific properties and are recombined into an effectively monoenergetic image, eliminating inaccuracies in material property estimation due to beam hardening. Use of a single instrument for simultaneous data collection also reduces technician time and floor space in a hospital.

Abstract: X-ray compensation masks (51) are prepared by exposing an X-ray target object (43), such as a patient, to a first beam of X-rays. The X-ray fluence from the patient is received by an electronic image receptor (44) which provides an output signal indicating the intensity of the X-rays at all positions in the image field. The image information is converted by an image processor (47) to transformed X-ray intensity values for a plurality of pixels which cover the image field. A mask generating controller (48) determines the minimum transformed intensity value for any pixel, assigns to each pixel an attenuation number which is proportional to the difference between the transformed intensity value for the pixel and the minimum transformed intensity value, and issues control signals to a mask former (49) which deposits on a non-attenuating substrate (50) attenuating masses in a two dimensional array of pixels with the mass thickness in each pixel proportional to the attenuation number.