Patents by Inventor Bruce Hammock

Bruce Hammock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of cis-Epoxyeicosantrienoic acids and inhibitors of soluble epoxide hydrolase to reduce pulmonary infiltration by neutrophils
    Publication number: 20050222252
    Abstract: It has now been discovered that inhibitors of soluble epoxide hydrolase (“sEH”) are useful in reducing the severity of or inhibiting the progression of obstructive pulmonary diseases, restrictive airway diseases, and asthma. Administering a cis-epoxyeicosantrienoic acid (“EET”) in addition to the inhibitor is at least additive, and may be synergistic, in reducing or inhibiting these conditions and diseases, as measured by reduced numbers of neutrophils present in the lung. The inhibitor of sEH may be a nucleic acid, such as a small interfering RNA.
    Type: Application
    Filed: March 31, 2004
    Publication date: October 6, 2005
    Applicant: The Regents of the University of California
    Inventors: Bruce Hammock, Kent Pinkerton, Kevin Smith, Takaho Watanabe, Seung Ma
  • Inhibitors for the soluble epoxide hydrolase
    Publication number: 20050164951
    Abstract: Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.
    Type: Application
    Filed: October 20, 2004
    Publication date: July 28, 2005
    Applicant: The Regents of the University of California
    Inventors: Bruce Hammock, In-Hae Kim, Christophe Morisseau, Takaho Watanabe, John Newman
  • Inhibitors for the soluble epoxide hydrolase
    Publication number: 20050026844
    Abstract: Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.
    Type: Application
    Filed: April 2, 2004
    Publication date: February 3, 2005
    Applicant: Regents of the University of California
    Inventors: Bruce Hammock, In-Hae Kim, Christophe Morisseau, Takaho Watanabe, John Newman
  • Linoleic acid diol and glucuronide conjugate levels as diagnostic markers of disorders of abnormal regulation of cytochrome P450 metabolism of unsaturated fatty acids
    Patent number: 6756210
    Abstract: The invention provides methods of using dihydroxy unsaturated fatty acids as markers for identifying patients with a disorder associated with abnormal regulation of the cytochrome P450 metabolism or oxidation of unsaturated fatty acids. For example, linoleic acid diols, including leukotoxindiol, can be used as a diagnostic tool for identifying patients with pre-eclampsia, eclampsia, and pregnancy-induced hypertension.
    Type: Grant
    Filed: May 29, 2001
    Date of Patent: June 29, 2004
    Assignee: The Regents of the University of California
    Inventors: Bruce Hammock, Gabriela Zurek, Shirley Gee, John W. Newman, Jiang Zheng
  • Dihydroxy unsaturated fatty acid levels as diagnostic markers
    Publication number: 20030113824
    Abstract: The invention provides methods of using dihydroxy unsaturated fatty acids as markers for identifying patients with a disorder associated with abnormal regulation of the cytochrome P450 metabolism or oxidation of unsaturated fatty acids. In preferred embodiments, linoleic acid diols, including, but not limited to, leukotoxindiol, are used as a diagnostic tool for identifying patients with pre-eclampsia, eclampsia, and pregnancy-induced hypertension.
    Type: Application
    Filed: May 29, 2001
    Publication date: June 19, 2003
    Inventors: Bruce Hammock, Gabriela Zurek, Shirley Gee, John William Newman