Patents by Inventor Bruce Hollander
Bruce Hollander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7863352Abstract: Polymer containing calcium sulfate particles as an implant material are provided. The polymer containing calcium sulfate particles include a calcium sulfate compound coated with a therapeutic polymer containing salicylate, with a coating thickness from about 2 ?m to about 50 ?m. The therapeutic polymer in the particles is in a range from about 0.1% to about 22% (w/w). The resorption of the particles in vivo is from about four weeks to about twenty weeks. The polymer containing calcium sulfate particles can be used as an implant material for bone repairing and bone augmentation.Type: GrantFiled: November 20, 2008Date of Patent: January 4, 2011Assignee: Orthogen LLCInventors: John L. Ricci, Harold Alexander, Bruce Hollander
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Publication number: 20090076188Abstract: Polymer containing calcium sulfate particles as an implant material are provided. The polymer containing calcium sulfate particles include a calcium sulfate compound coated with a therapeutic polymer containing salicylate, with a coating thickness from about 2 ?m to about 50 ?m. The therapeutic polymer in the particles is in a range from about 0.1% to about 22% (w/w). The resorption of the particles in vivo is from about four weeks to about twenty weeks. The polymer containing calcium sulfate particles can be used as an implant material for bone repairing and bone augmentation.Type: ApplicationFiled: November 20, 2008Publication date: March 19, 2009Inventors: John L. Ricci, Harold Alexander, Bruce Hollander
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Patent number: 7488761Abstract: An implant composition having controlled resorption rate in vivo for stimulating bone growth, a method of making the implant composition, and a kit of implant materials are disclosed. The implant composition includes a calcium sulfate compound, polymer containing particles, and a setting agent. The polymer is one or more poly(desaminotyrosyl-tyrosine alkyl ester carbonate). Upon setting, the calcium sulfate compound forms a matrix and the polymer containing particles settled within the matrix. The resorption rate of the implant composition in vivo can be controlled of between eight and twenty-four weeks, which substantially matches the rate of bone growth. The implant composition of the present invention can be used for the repair, augmentation, and other treatment of bone.Type: GrantFiled: July 14, 2004Date of Patent: February 10, 2009Assignee: Orthogen LLCInventors: John L. Ricci, Harold Alexander, Bruce Hollander
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Publication number: 20080015616Abstract: An orthopedic implant includes an implant element for surgical insertion into a bone of a patient, the implant element having a microgeometric repetitive surface pattern in the form of alternating ridges and grooves, each having a fixed or established width in a range of about 2.0 to about 25 microns (micrometers) and a fixed or established depth in a range of about 2 to about 25 microns, in which the microgemoetric repetitive patterns define a guide for preferential promotion of the rate, orientation and direction of growth colonies of cells of the bone which are in contact with the surface pattern.Type: ApplicationFiled: May 1, 2007Publication date: January 17, 2008Inventors: John Ricci, Harold Alexander, Charles Naiman, Harriet Naiman, Bruce Hollander, Ingo Kozak
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Publication number: 20050119758Abstract: An implant for surgical insertion into tissue of a patient includes a microgeometric, repetitive pattern, in the form of a multiplicity of alternating ridges and grooves, each having an established width in a range of about 2 to about 25 microns, and an established depth in a range of about 2 to about 25 microns, each groove having a base and a wall; and a microgeometric random surface pattern, applied over the repetitive surface pattern, defining a multiplicity of micro-pits having dimensions in a range of about 0.1 to about 4 microns.Type: ApplicationFiled: July 29, 2004Publication date: June 2, 2005Inventors: Harold Alexander, Bruce Hollander, John Ricci
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Publication number: 20050026798Abstract: A garbage disposal cleaning composition is disclosed, which includes a surfactant and a biodegradable natural particulate friction component. The biodegradable natural particulate friction component includes coffee grounds or ground nutshell such as black walnut shell, pecan shell, apricot shell or English walnut shell. The composition can further include antimicrobial, deodorizing agent, effervescent agent, builder, and fragrance. The garbage disposal cleaning composition can be in the form of tablet, liquid suspension, powder or gel. Also disclosed is the method of enhanced cleaning of a garbage disposal using the garbage disposal cleaning composition.Type: ApplicationFiled: July 27, 2004Publication date: February 3, 2005Inventor: Bruce Hollander
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Publication number: 20050026114Abstract: A method and devices for bone tissue expansion and compression for receiving a dental implant are disclosed. The method includes the steps of creating an initial osseotomy site in the maxilla or the mandable using a pilot drill; screwing a first threaded expander into the site to expand the site laterally; and allowing the expander staying in the site for a short time to impress the interior wall of the osseotomy site; then retrieving the first expander. These steps are repeated using a second, and/or third threaded expander having an increasing outer diameter to further expand the osseotomy site to a final diameter which is complementary, but narrower than the diameter of the dental implant so that expanded osseotomy site enables uniform engagement of the implant with the bone tissue. A preparation drilling to extend osseotomy site only at cortical level can be incorporated for hard bone and larger implants.Type: ApplicationFiled: July 30, 2003Publication date: February 3, 2005Inventors: Patricio Nilo, Bruce Hollander
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Publication number: 20040254259Abstract: An implant composition having controlled resorption rate in vivo for stimulating bone growth, a method of making the implant composition, and a kit of implant materials are disclosed. The implant composition includes a calcium sulfate compound, polymer containing particles, and a setting agent. The polymer is one or more poly(desaminotyrosyl-tyrosine alkyl ester carbonate). Upon setting, the calcium sulfate compound forms a matrix and the polymer containing particles settled within the matrix. The resorption rate of the implant composition in vivo can be controlled of between eight and twenty-four weeks, which substantially matches the rate of bone growth. The implant composition of the present invention can be used for the repair, augmentation, and other treatment of bone.Type: ApplicationFiled: July 14, 2004Publication date: December 16, 2004Inventors: John L. Ricci, Harold Alexander, Bruce Hollander
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Patent number: 6770695Abstract: An implant composition having controlled resorption rate in vivo for stimulating bone growth, a method of making the implant composition, and a kit of implant materials are disclosed. The implant composition includes a calcium sulfate compound, polymer containing particles, and a setting agent for setting the calcium sulfate compound and the polymer containing particles into a heterogeneous solid composition. Upon setting, the calcium sulfate compound forms a matrix and the polymer containing particles settled within the matrix. The resorption rate of the implant composition in vivo can be controlled of between eight and twenty-four weeks, which substantially matches the rate of bone growth. The implant composition of the present invention can be used for the repair, augmentation, and other treatment of bone.Type: GrantFiled: August 1, 2001Date of Patent: August 3, 2004Inventors: John L. Ricci, Harold Alexander, Bruce Hollander
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Patent number: 6582228Abstract: A surgical implant system includes an implant body and an osseostimulative surface applied to, or used with, the implant body, the surface including a calcium sulfate (CS) compound which is a member selected from the group consisting of CS dihydrate, CS hemihydrate, anhydrous CS, and mixtures thereof. The performance and rate of resorption of the osseostimulative surface may be improved or modified through the use of a stabilizing component, a viscosity modifier, a pH modifier, or a cell growth inductive microgeometry. The system is also definable in terms of an in situ system of bone augmentation in which a bio-resorbable CS matrix, in various physical forms, from a kit is disposed about the surgical implant positioned within an osseotomy site.Type: GrantFiled: January 22, 2001Date of Patent: June 24, 2003Inventors: John L. Ricci, Harold Alexander, Bruce Hollander, Ingo Kozak
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Patent number: 6406296Abstract: A dental implant for securement within a bore within a maxilla or mandible, inclusive of the cortical bone includes a threaded elongate anchor having a proximal upper portion having a larger outside diameter than that of an integral distal lower portion, the anchor defining, in axial cross-section, an envelope in which the upper portion substantially defines a cylinder and the lower portion substantially defines a conical section, and an engagable head integrally dependent from a proximal surface of the proximal portion of the anchor, the head having an outside diameter smaller than a greatest outside diameter of the proximal portion of the anchor, the outside diameter of the head also equal or less than a diameter of an entry region into the bore. A greatest axial length of the lower portion defines a length of about 6.0 mm.Type: GrantFiled: November 17, 2000Date of Patent: June 18, 2002Assignee: Bio-Lok International, Inc.Inventors: Bruce Hollander, Ingo Kozak
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Patent number: 6375464Abstract: A micromechanical seal between a first body and a second body is co-axially threadably securable about a portion of the first body. The seal is created by the combination of an annular planar radial surface within the first body; a surface of rotation of the first body disposed radially inwardly of the annular plane surface and defining, within a radial plane of the body, an obtuse angle, relative to the planar radial surface, in a range of about 90.Type: GrantFiled: September 25, 2000Date of Patent: April 23, 2002Assignee: BioLok International, Inc.Inventors: Bruce Hollander, Ingo Kozak
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Publication number: 20020016636Abstract: An implant composition having controlled resorption rate in vivo for stimulating bone growth, a method of making the implant composition, and a kit of implant materials are disclosed. The implant composition includes a calcium sulfate compound, polymer containing particles, and a setting agent for setting the calcium sulfate compound and the polymer containing particles into a heterogeneous solid composition. Upon setting, the calcium sulfate compound forms a matrix and the polymer containing particles settled within the matrix. The resorption rate of the implant composition in vivo can be controlled of between eight and twenty-four weeks, which substantially matches the rate of bone growth. The implant composition of the present invention can be used for the repair, augmentation, and other treatment of bone.Type: ApplicationFiled: August 1, 2001Publication date: February 7, 2002Inventors: John L. Ricci, Harold Alexander, Bruce Hollander
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Patent number: 6319005Abstract: A dental drill, formed of a substantially solid elongate body, includes (a) a longitudinal shank having a proximal and a distal end and having an axially disposed irrigation channel; (b) a working portion comprising (i) an annular boss integrally disposed distally of the shank; (ii) a neck of reduced radius relative to the boss, integrally disposed distally of the boss; (iii) a cutting region of uniform diameter integrally disposed distally of the neck; and (iv) a cutting region having a tapered external geometry, integrally dependant distally of the cutting region of uniform diameter, the cutting regions including at least four integral axi-symmetric flutes formed upon lateral surfaces of the regions, each of the flutes defining co-axial peripheral profiles, each of the flutes separated by substantially co-axial integral channels, each having at least one outlet therein, the working portion of the drill having an irrigation channel extending the entire length and integral with the shank irrigation, the one oType: GrantFiled: September 18, 2000Date of Patent: November 20, 2001Assignee: BioLok International Inc.Inventors: Bruce Hollander, Ingo Kozak
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Publication number: 20010032022Abstract: A surgical implant system includes an implant body and an osseostimulative surface applied to, or used with, the implant body, the surface including a calcium sulfate (CS) compound which is a member selected from the group consisting of CS dihydrate, CS hemihydrate, anhydrous CS, and mixtures thereof. The performance and rate of resorption of the osseostimulative surface may be improved or modified through the use of a stabilizing component, a viscosity modifier, a pH modifier, or a cell growth inductive microgeometry. The system is also definable in terms of an in situ system of bone augmentation in which a bio-resorbable CS matrix, in various physical forms, from a kit is disposed about the surgical implant positioned within an osseotomy site.Type: ApplicationFiled: January 22, 2001Publication date: October 18, 2001Inventors: John L. Ricci, Harold Alexander, Bruce Hollander, Ingo Kozak
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Patent number: 6224635Abstract: The present invention relates to techniques for the preparation and implantation of implants with surgical cements composed primarily of calcium sulfate (“CS”). The first of these novel techniques involves the steps of: (1.) precoating an implant with CS; (2.) permitting the implant to dry, and, (3.) thereafter grouting the implant in place with wet CS. The second embodiment involves: (1.) grouting an uncoated implant in place with wet CS. Finally, the third embodiment involves: (1.) precoating an implant with CS; (2.) permitting it to dry; and, (2.) subsequently press-fitting the implant in place without grouting.Type: GrantFiled: November 6, 1998Date of Patent: May 1, 2001Assignee: Hospital For Joint DiseasesInventors: John Ricci, Harold Alexander, Charles L. Berman, Sally Frenkel, Bruce Hollander, Gabriele Pecora
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Patent number: 6149432Abstract: A dental implant includes a rigid body having axially symmetric and radially circumferential spiral pitch surfaces, in a range of about 22 to about 28 pitch surfaces per axial inch, an upper concave bevel surface above each pitch surface, which is longer than a lower bevel surface beneath each pitch surface, and an intersection of each plane of each pitch surface, and each plane of each lower bevel surface defining a total included angle in a range of about 90 to about 130 degrees, the rigid body having minor thread diameters at intersections, between pitch surfaces, of the upper and lower bevel surfaces, the pitch surfaces and the minor thread diameters defining, at any axial radius of the rigid body, a ratio of thread pitch to thread depth in a range of about 1.25:1 to about 1.40:1. Each of the lower bevel surfaces define a total included angle in a range of about 20 to about 30 degrees relative to any given axial radius of the implant at a minor thread diameter.Type: GrantFiled: January 4, 1999Date of Patent: November 21, 2000Assignee: Biolok International, Inc.Inventors: Leon Shaw, Bruce Hollander
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Patent number: 6106292Abstract: A dental drill is formed of a solid elongate body, having a longitudinal shank including an axially disposed irrigation channel and a working portion having an annular boss and a neck of reduced radius relative to the boss, and a cutting region disposed distally of the neck, the cutting region including at least four axi-symmetric flutes formed upon lateral surfaces of the cutting region, each of the flutes defining co-axial peripheral profiles, each of the flutes separated by substantially co-axial channels, the working portion of the drill having an irrigation channel extending the entire length and having at least one outlet within each of the channels, the one outlet of each channel located proximally to a distal tip of the working portion, the tip defining a surface formed integrally and continuously with ends of the flutes and channels.Type: GrantFiled: August 2, 1999Date of Patent: August 22, 2000Assignee: Biolok International, Inc.Inventors: Bruce Hollander, Ingo Kozak