Patents by Inventor Bruce J. Dille

Bruce J. Dille has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleotide and amino acid sequences encoding an exported protein 1 derived from and uses thereof
    Patent number: 8318897
    Abstract: The present invention is directed to novel polynucleotides and polypeptides directed to EXP1 of Plasmodium vivax, and methods of using these polynucleotides and polypeptides in the detection of P. vivax antibodies or anti-P. vivax antibodies in a subject. The invention finds particular useful application in identifying recent exposure to P. vivax.
    Type: Grant
    Filed: August 29, 2011
    Date of Patent: November 27, 2012
    Assignee: Abbott Laboratories
    Inventors: Larry G. Birkenmeyer, Ruthie E. Coffey, George J. Dawson, Suresh M. Desai, Bruce J. Dille, Anthony Scott Muerhoff
  • and genes and uses thereof
    Patent number: 8268981
    Abstract: The subject invention relates to nucleic acid sequences and amino acid sequences encoded thereby, derived from the Merozoite Surface Protein (MSP1) gene of the Plasmodium species P. malariae and P. ovale. Such genes and proteins have many beneficial diagnostic as well as therapeutic uses.
    Type: Grant
    Filed: March 4, 2009
    Date of Patent: September 18, 2012
    Assignee: Abbott Laboratories
    Inventors: Larry G. Birkenmeyer, Anthony S. Muerhoff, Suresh M. Desai, George J. Dawson, Bruce J. Dille
  • NUCLEOTIDE AND AMINO ACID SEQUENCES ENCODING AN EXPORTED PROTEIN 1 DERIVED FROM PLASMODIUM VIVAX AND USES THEREOF
    Publication number: 20110311572
    Abstract: The present invention is directed to novel polynucleotides and polypeptides directed to EXP1 of Plasmodium vivax, and methods of using these polynucleotides and polypeptides in the detection of P. vivax antibodies or anti-P. vivax antibodies in a subject. The invention finds particular useful application in identifying recent exposure to P. vivax.
    Type: Application
    Filed: August 29, 2011
    Publication date: December 22, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Larry G. Birkenmeyer, Ruthie E. Coffey, George J. Dawson, Suresh M. Desai, Bruce J. Dille, Anthony S. Muerhoff
  • Nucleotide and amino acid sequences encoding an exported protein 1 derived from and uses thereof
    Patent number: 8063193
    Abstract: The present invention is directed to novel polynucleotides and polypeptides directed to EXP1 of Plasmodium vivax, and methods of using these polynucleotides and polypeptides in the detection of P. vivax antibodies or anti-P. vivax antibodies in a subject. The invention finds particular useful application in identifying recent exposure to P. vivax.
    Type: Grant
    Filed: March 27, 2009
    Date of Patent: November 22, 2011
    Assignee: Abbott Laboratories
    Inventors: Larry G. Birkenmeyer, Ruthie E. Coffey, George J. Dawson, Suresh M. Desai, Bruce J. Dille, Anthony S. Muerhoff
  • and genes and uses thereof
    Patent number: 8030471
    Abstract: The subject invention relates to nucleic acid sequences and amino acid sequences encoded thereby, derived from the Merozoite Surface Protein (MSP1) gene of the Plasmodium species P. malariae and P. ovale. Such genes and proteins have many beneficial diagnostic as well as therapeutic uses.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: October 4, 2011
    Assignee: Abbott Laboratories
    Inventors: Larry G. Birkenmeyer, Anthony S. Muerhoff, Suresh M. Desai, George J. Dawson, Bruce J. Dille
  • NUCLEOTIDE AND AMINO ACID SEQUENCES ENCODING AN EXPORTED PROTEIN 1 DERIVED FROM PLASMODIUM VIVAX AND USES THEREOF
    Publication number: 20100247576
    Abstract: The present invention is directed to novel polynucleotides and polypeptides directed to EXP1 of Plasmodium vivax, and methods of using these polynucleotides and polypeptides in the detection of P. vivax antibodies or anti-P. vivax antibodies in a subject. The invention finds particular useful application in identifying recent exposure to P. vivax.
    Type: Application
    Filed: March 27, 2009
    Publication date: September 30, 2010
    Applicant: Abbott Laboratories
    Inventors: Larry G. Birkenmeyer, Ruthie E. Coffey, George J. Dawson, Suresh M. Desai, Bruce J. Dille, Anthony S. Muerhoff
  • PLASMODIUM MALARIAE AND PLASMODIUM OVALE GENES AND USES THEREOF
    Publication number: 20090232797
    Abstract: The subject invention relates to nucleic acid sequences and amino acid sequences encoded thereby, derived from the Merozoite Surface Protein (MSP1) gene of the Plasmodium species P. malariae and P. ovale. Such genes and proteins have many beneficial diagnostic as well as therapeutic uses.
    Type: Application
    Filed: March 4, 2009
    Publication date: September 17, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: Larry G. Birkenmeyer, Anthony S. Muerhoff, Suresh M. Desai, George J. Dawson, Bruce J. Dille
  • PLASMODIUM MALARIAE AND PLASMODIUM OVALE GENES AND USES THEREOF
    Publication number: 20090226445
    Abstract: The subject invention relates to nucleic acid sequences and amino acid sequences encoded thereby, derived from the Merozoite Surface Protein (MSP1) gene of the Plasmodium species P. malariae and P. ovale. Such genes and proteins have many beneficial diagnostic as well as therapeutic uses.
    Type: Application
    Filed: June 20, 2008
    Publication date: September 10, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: Larry G. Birkenmeyer, Anthony S. Muerhoff, Suresh M. Desai, George J. Dawson, Bruce J. Dille
  • Amplification of target nucleic acids using gap filling ligase chain reaction
    Patent number: 5427930
    Abstract: An improved, "gap filling" embodiment of the Ligase Chain Reaction (LCR) is described. Gap filling LCR is LCR wherein at least one of the probes is recessed so that a gap is formed between the adjacent probes when they are hybridized to target. The gap is filled using polymerase and deoxyribonucleotide triphosphates before ligation of the probes together. There are single and double gap versions, depending on whether one or two probes are recessed and require filling before ligation. The improvement resides in selecting and using target sequences such that only a single type, or two types, of deoxyribonucleotide triphosphate(s) are required to fill double gaps each being 1-10 bases in length, preferably 1-3 bases. Probes having specific sequences are claimed for a number of pathogens.
    Type: Grant
    Filed: June 28, 1991
    Date of Patent: June 27, 1995
    Assignee: Abbott Laboratories
    Inventors: Larry G. Birkenmeyer, John J. Carrino, Bruce J. Dille, Hsiang-Yun Hu, Jon D. Kratochvil, Thomas G. Laffler, Ronald L. Marshall, Laurie A. Rinehardt, Natalie A. Solomon