Patents by Inventor Bruce J. Richardson
Bruce J. Richardson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20230191100Abstract: Fluid communication devices and supporting structures may be provided for use with intraosseous devices. Apparatus and methods may also be provided to communicate fluids with an intraosseous device.Type: ApplicationFiled: February 20, 2023Publication date: June 22, 2023Inventors: Larry J. MILLER, David S. BOLLETER, Robert W. TITKEMEYER, Joseph J. MANNO, Matthew T. HARMON, Bruce J. RICHARDSON, Gary Emerson HART
-
Patent number: 11583668Abstract: Fluid communication devices and supporting structures may be provided for use with intraosseous devices. Apparatus and methods may also be provided to communicate fluids with an intraosseous device.Type: GrantFiled: April 1, 2019Date of Patent: February 21, 2023Assignee: TELEFLEX LIFE SCIENCES LIMITEDInventors: Larry J. Miller, David S. Bolleter, Robert W. Titkemeyer, Joseph J. Manno, Matthew T. Harmon, Bruce J. Richardson, Gary Emerson Hart
-
Publication number: 20190224464Abstract: Fluid communication devices and supporting structures may be provided for use with intraosseous devices. Apparatus and methods may also be provided to communicate fluids with an intraosseous device.Type: ApplicationFiled: April 1, 2019Publication date: July 25, 2019Inventors: Larry J. MILLER, David S. BOLLETER, Robert W. TITKEMEYER, Joseph J. MANNO, Matthew T. HARMON, Bruce J. RICHARDSON, Gary Emerson HART
-
Publication number: 20190194765Abstract: Systems and methods for detecting and/or identifying target cells (e.g., bacteria) using engineered transduction particles are described herein. In some embodiments, a method includes mixing a quantity of transduction particles within a sample. The transduction particles are associated with a target cell. The transduction particles are non-replicative, and are engineered to include a nucleic acid molecule formulated to cause the target cell to produce a series of reporter molecules. The sample and the transduction particles are maintained to express the series of the reporter molecules when target cell is present in the sample. A signal associated with a quantity of the reporter molecules is received. In some embodiments, a magnitude of the signal is independent from a quantity of the transduction particle above a predetermined quantity.Type: ApplicationFiled: February 27, 2019Publication date: June 27, 2019Applicant: GeneWeave Biosciences, Inc.Inventors: Diego Ariel REY, Shaunak ROY, Leonardo Maestri TEIXEIRA, Ryan C. GRISWOLD, Kenneth G. OLSON, Bruce J. RICHARDSON, Victor H. YEE, Werner FREI
-
Patent number: 10258783Abstract: Fluid communication devices and supporting structures may be provided for use with intraosseous devices. Apparatus and methods may also be provided to communicate fluids with an intraosseous device.Type: GrantFiled: March 10, 2015Date of Patent: April 16, 2019Assignee: TELEFLEX MEDICAL DEVICES S.À R.L.Inventors: Larry J. Miller, David S. Bolleter, Robert W. Titkemeyer, Joseph J. Manno, Matthew T. Harmon, Bruce J. Richardson, Gary Emerson Hart
-
Patent number: 10240212Abstract: Systems and methods for detecting and/or identifying target cells (e.g., bacteria) using engineered transduction particles are described herein. In some embodiments, a method includes mixing a quantity of transduction particles within a sample. The transduction particles are associated with a target cell. The transduction particles are non-replicative, and are engineered to include a nucleic acid molecule formulated to cause the target cell to produce a series of reporter molecules. The sample and the transduction particles are maintained to express the series of the reporter molecules when target cell is present in the sample. A signal associated with a quantity of the reporter molecules is received. In some embodiments, a magnitude of the signal is independent from a quantity of the transduction particle above a predetermined quantity.Type: GrantFiled: December 22, 2016Date of Patent: March 26, 2019Assignee: GeneWeave Biosciences, Inc.Inventors: Diego Ariel Rey, Shaunak Roy, Leonardo Maestri Teixeira, Ryan C. Griswold, Kenneth G. Olson, Bruce J. Richardson, Victor H. Yee, Werner Frei
-
Patent number: 10125386Abstract: An apparatus includes a housing and an actuator. The housing, which defines a reagent volume that can receive a reagent container, can be removably coupled to a reaction chamber. The housing includes a puncturer that defines a transfer pathway in fluid communication with the reagent volume. A delivery portion of the housing defines a delivery pathway between the transfer pathway and the reaction chamber when the housing is coupled to the reaction chamber. The actuator has a plunger portion disposed within the reagent volume. An engagement portion of the actuator can be manipulated to move the plunger portion within the reagent volume to deform the reagent container. The puncturer can pierce a frangible portion of the reagent container to convey a reagent from the reagent container into the reaction chamber via the transfer pathway and/or the delivery pathway.Type: GrantFiled: November 30, 2016Date of Patent: November 13, 2018Assignee: GeneWeave Biosciences, Inc.Inventors: Nikol De Forest, Werner Frei, Diego Rey, Shaunak Roy, Soni Shukla, Ryan C. Griswold, Kenneth G. Olson, Bruce J. Richardson, Victor H. Yee
-
Publication number: 20170233783Abstract: An apparatus includes a housing and an actuator. The housing, which defines a reagent volume that can receive a reagent container, can be removably coupled to a reaction chamber. The housing includes a puncturer that defines a transfer pathway in fluid communication with the reagent volume. A delivery portion of the housing defines a delivery pathway between the transfer pathway and the reaction chamber when the housing is coupled to the reaction chamber. The actuator has a plunger portion disposed within the reagent volume. An engagement portion of the actuator can be manipulated to move the plunger portion within the reagent volume to deform the reagent container. The puncturer can pierce a frangible portion of the reagent container to convey a reagent from the reagent container into the reaction chamber via the transfer pathway and/or the delivery pathway.Type: ApplicationFiled: November 30, 2016Publication date: August 17, 2017Applicant: GeneWeave Biosciences, Inc.Inventors: Nikol DE FOREST, Werner FREI, Diego Rey, Shaunak Roy, Soni SHUKLA, Ryan C. GRISWOLD, Kenneth G. OLSON, Bruce J. RICHARDSON, Victor H. Yee
-
Publication number: 20170152576Abstract: Systems and methods for detecting and/or identifying target cells (e.g., bacteria) using engineered transduction particles are described herein. In some embodiments, a method includes mixing a quantity of transduction particles within a sample. The transduction particles are associated with a target cell. The transduction particles are non-replicative, and are engineered to include a nucleic acid molecule formulated to cause the target cell to produce a series of reporter molecules. The sample and the transduction particles are maintained to express the series of the reporter molecules when target cell is present in the sample. A signal associated with a quantity of the reporter molecules is received. In some embodiments, a magnitude of the signal is independent from a quantity of the transduction particle above a predetermined quantity.Type: ApplicationFiled: December 22, 2016Publication date: June 1, 2017Applicant: GeneWeave Biosciences, Inc.Inventors: Diego Ariel REY, Shaunak ROY, Leonardo Maestri TEIXEIRA, Ryan C. GRISWOLD, Kenneth G. OLSON, Bruce J. RICHARDSON, Victor H. YEE
-
Patent number: 9579646Abstract: An automated multi-function processing head for a laboratory work station having a table for supporting microtiter plates, other fluid receptacles, a movable arm, and a dual tip dispensing head affixed for reciprocal movement along the arm. The workstation combines into a single programmable system the capabilities for automation of a wide range of bioanalytical procedures including sample pipetting, serial dilution, reagent additions, mixing, reaction timing and washing of reaction vessels. The work station is adapted to transfer, dispense and aspirate liquid from one location to another automatically in accordance with user programmed instructions. Fluid is dispensed and aspirated using a dual tip dispensing head having two sets of tip couplers actuated by one drive system. The two sets of tip couplers allow the use of different sizes of pipette tips and tips at different pitches or distances between the centerlines.Type: GrantFiled: July 24, 2015Date of Patent: February 28, 2017Assignee: ACCEL BIOTECH, INC.Inventor: Bruce J. Richardson
-
Patent number: 9546391Abstract: Systems and methods for detecting and/or identifying target cells (e.g., bacteria) using engineered transduction particles are described herein. In some embodiments, a method includes mixing a quantity of transduction particles within a sample. The transduction particles are associated with a target cell. The transduction particles are non-replicative, and are engineered to include a nucleic acid molecule formulated to cause the target cell to produce a series of reporter molecules. The sample and the transduction particles are maintained to express the series of the reporter molecules when target cell is present in the sample. A signal associated with a quantity of the reporter molecules is received. In some embodiments, a magnitude of the signal is independent from a quantity of the transduction particle above a predetermined quantity.Type: GrantFiled: September 8, 2014Date of Patent: January 17, 2017Assignee: GeneWeave Biosciences, Inc.Inventors: Diego Ariel Rey, Shaunak Roy, Werner Frei, Bruce J. Richardson, Ryan C. Griswold, Damian S. Matthews, Kenneth G. Olson, Victor H. Yee
-
Patent number: 9540675Abstract: An apparatus includes a housing and an actuator. The housing, which defines a reagent volume that can receive a reagent container, can be removably coupled to a reaction chamber. The housing includes a puncturer that defines a transfer pathway in fluid communication with the reagent volume. A delivery portion of the housing defines a delivery pathway between the transfer pathway and the reaction chamber when the housing is coupled to the reaction chamber. The actuator has a plunger portion disposed within the reagent volume. An engagement portion of the actuator can be manipulated to move the plunger portion within the reagent volume to deform the reagent container. The puncturer can pierce a frangible portion of the reagent container to convey a reagent from the reagent container into the reaction chamber via the transfer pathway and/or the delivery pathway.Type: GrantFiled: February 9, 2015Date of Patent: January 10, 2017Assignee: GeneWeave Biosciences, Inc.Inventors: Nikol De Forest, Werner Frei, Diego Rey, Shaunak Roy, Soni Shukla, Ryan C. Griswold, Kenneth G. Olson, Bruce J. Richardson, Victor H. Yee
-
Patent number: 9481903Abstract: Systems and methods for detecting and/or identifying target cells (e.g., bacteria) using engineered transduction particles are described herein. In some embodiments, a method includes mixing a quantity of transduction particles within a sample. The transduction particles are associated with a target cell. The transduction particles are non-replicative, and are engineered to include a nucleic acid molecule formulated to cause the target cell to produce a series of reporter molecules. The sample and the transduction particles are maintained to express the series of the reporter molecules when target cell is present in the sample. A signal associated with a quantity of the reporter molecules is received. In some embodiments, a magnitude of the signal is independent from a quantity of the transduction particle above a predetermined quantity.Type: GrantFiled: March 13, 2013Date of Patent: November 1, 2016Assignee: Roche Molecular Systems, Inc.Inventors: Diego Ariel Rey, Shaunak Roy, Leonardo Maestri Teixeira, Ryan C. Griswold, Kenneth G. Olson, Bruce J. Richardson, Victor Yee
-
Publication number: 20160023213Abstract: A tool which may be picked up by a dispense head and coupled to a pipette tip coupler. The pipette tip coupler can manipulate gripping arms of the tool using the tip ejection members. A microplate can be transported by this took, the tool parked at a parking location, and the pipette tip coupler used for other uses, such as aspirating or dispensing liquid when pipette tip is coupled onto the pipette tip coupler.Type: ApplicationFiled: July 24, 2015Publication date: January 28, 2016Applicant: Accel Biotech, Inc.Inventor: Bruce J. Richardson
-
Publication number: 20160023203Abstract: An automated multi-function processing head for a laboratory work station having a table for supporting microtiter plates, other fluid receptacles, a movable arm, and a dual tip dispensing head affixed for reciprocal movement along the arm. The workstation combines into a single programmable system the capabilities for automation of a wide range of bioanalytical procedures including sample pipetting, serial dilution, reagent additions, mixing, reaction timing and washing of reaction vessels. The work station is adapted to transfer, dispense and aspirate liquid from one location to another automatically in accordance with user programmed instructions. Fluid is dispensed and aspirated using a dual tip dispensing head having two sets of tip couplers actuated by one drive system. The two sets of tip couplers allow the use of different sizes of pipette tips and tips at different pitches or distances between the centerlines.Type: ApplicationFiled: July 24, 2015Publication date: January 28, 2016Applicant: ACCEL BIOTECH, INC.Inventor: Bruce J. Richardson
-
Publication number: 20160003717Abstract: The present invention generally discloses an extraction system that provides a locale for fluid processing and extraction on a post-microcapture transfer film. The extraction system includes a transfer film carrier and an extraction device forming a reservoir. The extraction system selectively excludes regions of the transfer film from the reservoir to advantageously reduce contamination due to matter adhered to the transfer film by non-specific transfer.Type: ApplicationFiled: July 10, 2015Publication date: January 7, 2016Inventors: Thomas M. BAER, Robert H. REAMEY, Keith E. MORAVICK, David F. HEAD, Bruce J. RICHARDSON, Derrick RICHARDSON
-
Publication number: 20150351797Abstract: Fluid communication devices and supporting structures may be provided for use with intraosseous devices. Apparatus and methods may also be provided to communicate fluids with an intraosseous device.Type: ApplicationFiled: March 10, 2015Publication date: December 10, 2015Applicant: VIDACARE LLCInventors: Larry J. Miller, David S. Bolleter, Robert W. Titkemeyer, Joseph J. Manno, Matthew T. Harmon, Bruce J. Richardson, Gary Emerson Hart
-
Publication number: 20150308957Abstract: A method and apparatus for performing melting curve analyses of nucleic acids on a microarray is described. The present method includes varying the temperature of a fluid on a microarray to dissociate and remove target DNA, scanning the mircoarray for fluorescence, collecting the target DNA removed from the microarray, and reusing the collected target DNA and the microarray. The apparatus of the present disclosure includes a microarray stage, a light source and detector, and a temperature controller, wherein the temperature controller is configured to adjust the temperature of a fluid within a sample chamber on the microarray such that the temperature of the fluid is varied during the analysis such that target DNA is dissociated from the microarray, and wherein the light source is directed to the microarray and the resulting fluorescence is perceived by the detector.Type: ApplicationFiled: July 7, 2015Publication date: October 29, 2015Inventors: Michael Okura, Bruce J. Richardson
-
Patent number: 9133497Abstract: Systems and methods for detecting and/or identifying target cells (e.g., bacteria) using engineered transduction particles are described herein. In some embodiments, a method includes mixing a quantity of transduction particles within a sample. The transduction particles are associated with a target cell. The transduction particles are non-replicative, and are engineered to include a nucleic acid molecule formulated to cause the target cell to produce a series of reporter molecules. The sample and the transduction particles are maintained to express the series of the reporter molecules when target cell is present in the sample. A signal associated with a quantity of the reporter molecules is received. In some embodiments, a magnitude of the signal is independent from a quantity of the transduction particle above a predetermined quantity.Type: GrantFiled: February 2, 2015Date of Patent: September 15, 2015Assignee: GeneWeave Biosciences, Inc.Inventors: Werner Frei, Diego Ariel Rey, Shaunak Roy, Ryan C. Griswold, Kenneth G. Olson, Bruce J. Richardson, Rick V. Stellmacher
-
Patent number: 9103785Abstract: A method and apparatus for performing melting curve analyses of nucleic acids on a microarray is described. The present method includes varying the temperature of a fluid on a microarray to dissociate and remove target DNA, scanning the mircoarray for fluorescence, collecting the target DNA removed from the microarray, and reusing the collected target DNA and the microarray. The apparatus of the present disclosure includes a microarray stage, a light source and detector, and a temperature controller, wherein the temperature controller is configured to adjust the temperature of a fluid within a sample chamber on the microarray such that the temperature of the fluid is varied during the analysis such that target DNA is dissociated from the microarray, and wherein the light source is directed to the microarray and the resulting fluorescence is perceived by the detector.Type: GrantFiled: June 25, 2009Date of Patent: August 11, 2015Assignee: Emergence Genomics, LLCInventors: Michael Okura, Bruce J. Richardson