Patents by Inventor Bruce K. Hamilton

Bruce K. Hamilton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for using synthetic analogs of thrombospondin for inhibiting angiogenesis activity
    Patent number: 5506208
    Abstract: Methods of use of compounds and compositions comprising fragments and synthetic analogs of human thrombospondin are provided for promoting or inhibiting thrombospondin-like activity.
    Type: Grant
    Filed: March 22, 1995
    Date of Patent: April 9, 1996
    Assignees: W. R. Grace & Co.-Conn., The Medical College of Pennsylvania
    Inventors: Jacob Eyal, Bruce K. Hamilton, George P. Tuszynski
  • Cys-Ser-Val-Thr-Cys-Gly specific tumor cell adhesion receptor
    Patent number: 5367059
    Abstract: The present invention provides a cell matrix receptor specific for the Cys Ser Val Thr Cys Gly (SEQ ID NO: 1) region of thrombospondin. Also provided are purification, cloning and expression methods. Antibodies directed against the receptor protein are useful in numerous diagnostic, prophylactic and therapeutic areas.
    Type: Grant
    Filed: May 14, 1992
    Date of Patent: November 22, 1994
    Assignees: W. R. Grace & Co.-Conn., The Medical College of PA
    Inventors: George P. Tuszynski, Jacob Eyal, Bruce K. Hamilton
  • Method for using synthetic analogs of thrombospondin for inhibiting metastasis activity
    Patent number: 5190920
    Abstract: Compounds and compositions comprising fragments and methods for using synthetic analogs of thrombospondin for promoting or inhbiting thrombospondin-like activity are provided.
    Type: Grant
    Filed: September 24, 1990
    Date of Patent: March 2, 1993
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: Jacob Eyal, Bruce K. Hamilton, George P. Tuszynski