Abstract: Amniotic fluid stem cell clones are provided. Also provided are pharmaceutical compositions comprising the amniotic fluid stem cell clones, methods of generating the amniotic fluid stem cell clones, and methods of using the amniotic fluid stem cell clones, including for treating subjects and for bioassays.

Abstract: Homogeneous human amniotic fluid stem cell clones are provided. The clones serve as direct bioassays to test the effect of drugs, nutraceuticals, vitamins and toxic agents on fetus growth, differentiation and development, and may be administered in form of pharmaceutical compositions for reconstructive engineering and for the treatment of cardiac, neurological and osteoarthritic diseases.

Abstract: A vaginal speculum comprising a supporting base oriented generally vertically. A blade extends from the base and the angle between the blade and the base is adjustable. A locking system has an unlocked position allowing the blade to be angularly moved with respect to the base and a locked position retaining the blade at that desired angle. The vaginal speculum may also have two blades, a posterior blade having the angular adjustment and an anterior blade adjustably affixed to the base such that the space between the blades may be selectively adjusted by the physician. One or both of the blades may have a plastic sleeves slidably affixed thereto. Preferably, there is a plurality of sleeves of different lengths and/or widths that can be selected and attached to the blades depending on the particular patient. That selection can be made from a kit readily available to the physician.