Patents by Inventor Bruce Kerwin

Bruce Kerwin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microneedle array patches (MAPs), systems, and methods for manufacturing and using same
    Patent number: 12636250
    Abstract: Dispensable formulations, microneedles, microarray patches (MAPs), and systems that can facilitate simple, substantially pain-free, and consistent delivery of a wide range of active pharmaceutical ingredients (APIs) and doses, as well as methods of manufacturing and using the same are described herein.
    Type: Grant
    Filed: March 5, 2025
    Date of Patent: May 26, 2026
    Assignee: Terrestrial Bio, Inc.
    Inventors: Lynda Tussey, Matthew Dirckx, Rebecca Crawley, Bruce Kerwin, Himabindu Nandivada Bailey, Jane Maeng, John Spiridigliozzi, Jonathan A. Kluge, Michael Isidoro, Logan McElhinney, Matthew Vargas
  • MICRONEEDLE ARRAY PATCHES (MAPS), SYSTEMS, AND METHODS FOR MANUFACTURING AND USING SAME
    Publication number: 20260007869
    Abstract: Dispensable formulations, microneedles, microarray patches (MAPs), and systems that can facilitate simple, substantially pain-free, and consistent delivery of a wide range of active pharmaceutical ingredients (APIs) and doses, as well as methods of manufacturing and using the same are described herein.
    Type: Application
    Filed: December 26, 2024
    Publication date: January 8, 2026
    Applicant: VAXESS TECHNOLOGIES, INC.
    Inventors: Lynda Tussey, Matthew Dirckx, Rebecca Crawley, Bruce Kerwin, Himabindu Nandivada Bailey, Jane Maeng, John Spiridigliozzi, Jonathan A. Kluge, Jonathan Portman, Anna Markowska, Michael Isidoro, Logan Mcelhinney, Matthew Vargas, Kathryn M. Kosuda, Cassie L. Caudill, Matthew Manganiello, Alexander Beliveau, Samir Gadhia, Dylan Miller
  • MICRONEEDLE ARRAY PATCHES (MAPS), SYSTEMS, AND METHODS FOR MANUFACTURING AND USING SAME
    Publication number: 20250248925
    Abstract: Dispensable formulations, microneedles, microarray patches (MAPs), and systems that can facilitate simple, substantially pain-free, and consistent delivery of a wide range of active pharmaceutical ingredients (APIs) and doses, as well as methods of manufacturing and using the same are described herein.
    Type: Application
    Filed: March 5, 2025
    Publication date: August 7, 2025
    Applicant: VAXESS TECHNOLOGIES, INC.
    Inventors: Lynda Tussey, Matthew Dirckx, Rebecca Crawley, Bruce Kerwin, Himabindu Nandivada Bailey, Jane Maeng, John Spiridigliozzi, Jonathan A. Kluge, Jonathan Portman, Anna Markowska, Michael Isidoro, Logan McElhinney, Matthew Vargas, Kathryn M. Kosuda, Cassie L. Caudill, Matthew Manganiello, Alexander Beliveau, Samir Gadhia, Dylan Miller
  • METHODS OF REDUCING AGGREGATION OF IL-1RA
    Publication number: 20210121571
    Abstract: Methods of reducing aggregation of an aggregating IL-1ra comprising incubating IL-1ra with at least one accessory molecule are provided. Kits comprising IL-1ra and at least one accessory molecule are also provided. Pharmaceutical compositions comprising IL-1ra and at least one accessory molecule are also provided.
    Type: Application
    Filed: July 31, 2020
    Publication date: April 29, 2021
    Applicant: SWEDISH ORPHAN BIOVITRUM AB (PUBL)
    Inventors: Andrei RAIBEKAS, Bruce KERWIN
  • Methods of reducing aggregation of IL-1ra
    Patent number: 10765747
    Abstract: Methods of reducing aggregation of an aggregating IL-1ra comprising incubating IL-1ra with at least one accessory molecule are provided. Kits comprising IL-1ra and at least one accessory molecule are also provided. Pharmaceutical compositions comprising IL-1ra and at least one accessory molecule are also provided.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: September 8, 2020
    Assignee: SWEDISH ORPHAN BIOVITRUM AB (PUBL)
    Inventors: Andrei Raibekas, Bruce Kerwin
  • COMPOSITIONS OF PEGYLATED SOLUBLE TUMOR NECROSIS FACTOR RECEPTORS AND METHODS OF PREPARING
    Publication number: 20100197751
    Abstract: The present invention provides for improved compositions comprising a PEGsTNF-R1 which, in addition to having useful higher concentrations, demonstrate decreased viscosity (<400 cP) and improved stability.
    Type: Application
    Filed: April 29, 2009
    Publication date: August 5, 2010
    Inventors: Bruce Kerwin, Byeong Chang, Lei Shi
  • Compositions of pegylated soluble tumor necrosis factor receptors and methods of preparing
    Patent number: 7700722
    Abstract: The present invention provides for improved compositions comprising a PEGsTNF-R1 which, in addition to having useful higher concentrations, demonstrate decreased viscosity (<400 cP) and improved stability.
    Type: Grant
    Filed: June 12, 2003
    Date of Patent: April 20, 2010
    Assignee: Amgen Inc.
    Inventors: Bruce Kerwin, Byeong Chang, Lei Shi
  • IL-1ra variants
    Patent number: 7619066
    Abstract: The present invention provides for an IL-1ra having reduced aggregation, methods of reducing aggregation of IL-1ra, and kits comprising an IL-1ra having reduced aggregation.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: November 17, 2009
    Assignee: Amgen Inc.
    Inventors: Andrei Raibekas, Bruce Kerwin
  • Methods of reducing aggregation of IL-1ra
    Publication number: 20070098684
    Abstract: Methods of reducing aggregation of an aggregating IL-1ra comprising incubating IL-1ra with at least one accessory molecule are provided. Kits comprising IL-1ra and at least one accessory molecule are also provided. Pharmaceutical compositions comprising IL-1ra and at least one accessory molecule are also provided.
    Type: Application
    Filed: April 1, 2005
    Publication date: May 3, 2007
    Inventors: Andrei Raibekas, Bruce Kerwin
  • IL-1ra variants
    Publication number: 20050282752
    Abstract: The present invention provides for an IL-1ra having reduced aggregation, methods of reducing aggregation of IL-1ra, and kits comprising an IL-1ra having reduced aggregation.
    Type: Application
    Filed: April 1, 2005
    Publication date: December 22, 2005
    Inventors: Andrei Raibekas, Bruce Kerwin
  • Methods of reducing aggregation of IL-1ra
    Publication number: 20050271618
    Abstract: Methods of reducing aggregation of an aggregating IL-1ra comprising incubating IL-1ra with at least one accessory molecule are provided. Kits comprising IL-1ra and at least one accessory molecule are also provided. Pharmaceutical compositions comprising IL-1ra and at least one accessory molecule are also provided.
    Type: Application
    Filed: April 1, 2005
    Publication date: December 8, 2005
    Inventors: Andrei Raibekas, Bruce Kerwin
  • Compositions of pegylated soluble tumor necrosis factor receptors and methods of preparing
    Publication number: 20040002451
    Abstract: The present invention provides for improved compositions comprising a PEGsTNF-R1 which, in addition to having useful higher concentrations, demonstrate decreased viscosity (<400 cP) and improved stability.
    Type: Application
    Filed: June 20, 2002
    Publication date: January 1, 2004
    Inventors: Bruce Kerwin, Byeong Chang, Lei Shi
  • Compositions of pegylated soluble tumor necrosis factor receptors and methods of preparing
    Publication number: 20030236196
    Abstract: The present invention provides for improved compositions comprising a PEGsTNF-R1 which, in addition to having useful higher concentrations, demonstrate decreased viscosity (<400 cP) and improved stability.
    Type: Application
    Filed: June 12, 2003
    Publication date: December 25, 2003
    Applicant: Amgen Inc.
    Inventors: Bruce Kerwin, Byeong Chang, Lei Shi