Abstract: Novel nanowell microarrays are disclosed in optical contact with polymer waveguides wherein evanescent field associated with lightwaves propagated in the waveguide excite target substances in the nanowells either by a common waveguide or by individual waveguides. Fluid samples are conveyed to the nanowells by means of microfluidics. The presence of the target substances in fluid samples is detected by sensing fluorescent radiation generated by fluorescent tag bound to the target substances. The fluorescent tags generate fluorescent radiation as a result of their excitation by the evanescent field. One or more PMT detectors or a CCD detector are located at the side of the waveguide opposite to the nanowells. Fluorescent radiation is detected due to its coupling with the waveguide or its emission through the waveguide.

Abstract: Novel nanowell microarrays are disclosed in optical contact with polymer waveguides wherein evanescent field associated with lightwaves propagated in the waveguide excite target substances in the nanowells either by a common waveguide or by individual waveguides. Fluid samples are conveyed to the nanowells by means of microfluidics. The presence of the target substances in fluid samples is detected by sensing fluorescent radiation generated by fluorescent tag bound to the target substances. The fluorescent tags generate fluorescent radiation as a result of their excitation by the evanescent field. One or more PMT detectors or a CCD detector are located at the side of the waveguide opposite to the nanowells. Fluorescent radiation is detected due to its coupling with the waveguide or its emission through the waveguide.

Abstract: An improved, lower cost, optical fiber interconnect device of the type known as a “perfect shuffle” and processes for the preparation thereof. The present invention relates to devices that are smaller in size than prior art devices and that exhibit superior optical properties including lower attenuation loss (lower insertion loss) and to processes which produce such devices.

Abstract: Optical waveguide devices for interconnecting optical fibers and use in integrated optical systems. The invention includes a substantially dry method for making the devices and intermediate elements.

Abstract: Optical waveguide connectors for coupling arrays of waveguides and/or optical fibers and to methods of making the connectors. The connectors are optical waveguide or optical fiber connectors for coupling to mating optical waveguide or optical fiber connectors. Optical connector assemblies are provided which comprise optical waveguide or optical fiber connectors in combination with mating optical waveguide or optical fiber connectors. Methods of manufacturing the optical waveguide or optical fiber connectors and the optical connector assemblies are disclosed.

Abstract: A substantially dry method for making an optical waveguide device with at least one buried channel waveguide in a laminated and hardened matrix. The method begins with exposing to light a region of a substantially dry photohardenable film adhered to a support. Then a first substantially dry photohardenable layer which is adhered to a support is laminated to one side of the film. Then the support is removed from the film. Then a second substantially dry photohardenable layer which is adhered to a support is laminated to the other side of the film. Then the layers and film are hardened.

Abstract: This invention relates to organic optical waveguide devices which have improved barrier properties after having been coated with silicon monoxide, and then with silicon dioxide doped with certain metals.

Abstract: A method of coupling an optical fiber with an optical waveguide device at an elevated temperature, through a symmetrical opening, in the presence of a liquid photohardenable composition, in order to extend the operability of the coupling over a wide range of temperatures.

Abstract: A diffraction grating is created in the branching region of a photopolymer waveguide, preferably by directing onto the branching region coherent light through a hologram of a grating or by intersecting two or more coherent light beams on the branching region in a regular grating pattern.

Abstract: An optical waveguide device adaptable to be coupled with a similar optical waveguide device through commensurate slots on the devices, the slots guiding the ends of the respective waveguides into contact with each other, and into properly aligned optical coupling.

Abstract: Optical waveguide devices have improved barrier properties after having been coated with silicon dioxide doped with certain metals.

Abstract: An optical switch for switching light from one leg of an optical circuit to another leg is characterized by an arrangement for altering the index of refraction of one of the legs with respect to the other leg. This results in a disparity in light velocity and a change in phase relationship for the light being propagated through the legs. When the legs are brought into a coupling region, there occurs a predetermined transfer of light from one leg to the other, depending upon the magnitude of the alteration in phase relationship between the light propagated in the legs.

Abstract: Methods of making assemblies and assemblies for interconnecting optical fibers and use in integrated optical systems. The optical fiber connector assemblies include a pedestal having a step supporting an optical waveguide device having a buried waveguide. End portions of the step support means for receiving cores and cladding of optical fibers with the optical axes of the cores in alignment with the optical axis or axes of the waveguide.

Abstract: Methods of making assemblies and assemblies for interconnecting optical fibers and use in integrated optical systems. The optical fiber connector assemblies include a pedestal having a step supporting an optical waveguide device having a buried waveguide. End portions of the step support means for receiving cores and cladding of optical fibers with the optical axes of the cores in alignment with the optical axis or axes of the waveguide.