Patents by Inventor Bruce L. Gibbins
Bruce L. Gibbins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10251392Abstract: The present invention comprises methods and compositions for antimicrobial devices comprising metal containing compositions which are resistant to heat and light discoloration. The metal containing compositions may comprise salts or complexes of silver, copper or zinc. In one aspect the compositions comprise silver salts. In another aspect, the compositions comprise silver complexes. In one aspect, the metal salts may comprise metal salts of saccharin, acesulfame, long chain fatty acids, and alkyl dicarboxylic acids. The compositions further comprise polymers which form salts or complexes with silver, copper or zinc. The methods of the present invention comprise treating devices with the metal containing compositions, including, but not limited to, such devices as woven wound care materials, catheters, patient care devices, and collagen matrices. The present invention further comprises treatment of humans and animals with the antimicrobial devices described herein.Type: GrantFiled: August 1, 2005Date of Patent: April 9, 2019Assignee: Avent, Inc.Inventors: Bhalchandra M. Karandikar, Bruce L. Gibbins, Ken A. Cornell
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Patent number: 9888691Abstract: The present invention comprises methods and compositions for antimicrobial silver compositions comprising silver nanoparticles. The present invention further comprises compositions for preparing silver nanoparticles comprising at least one stabilizing agent, one or more silver compounds, at least one reducing agent and a solvent. In one aspect, the stabilizing agent comprises a surfactant or a polymer. The polymer may comprise polymers such as polyacrylamides, polyurethanes, and polyamides. In one aspect, the silver compound comprises a salt comprising a silver cation and an anion. The anion may comprise saccharinate derivatives, long chain fatty acids, and alkyl dicarboxylates. The methods of the present invention comprise treating devices with the silver nanoparticle compositions, including, but not limited to, such devices as woven wound care materials, catheters, patient care devices, and collagen matrices.Type: GrantFiled: November 18, 2014Date of Patent: February 13, 2018Assignee: Avent, Inc.Inventors: Bhalchandra M. Karandikar, Bruce L. Gibbins, Kenneth A. Cornell
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Patent number: 9783676Abstract: An antimicrobial polyurethane foam that is formed from: a multi-functional isocyanate component; an aqueous polyol component reactive with the multi-functional isocyanate component; an antimicrobial metallic compound; and a complexing agent. The complexing agent is used to form a stable blend of the antimicrobial metallic compound with the polyol component. Exemplary complexing agents include amine compounds, ammonium-containing compounds, and ammonia as well as combinations of these compounds. The antimicrobial metallic compound can be a silver, zinc, or copper compound. Desirably, the antimicrobial metallic compound is silver saccharinate. A process of making the antimicrobial polyurethane foam and stable blends used in the manufacture of the antimicrobial polyurethane foam are also disclosed.Type: GrantFiled: November 11, 2015Date of Patent: October 10, 2017Assignee: Avent, Inc.Inventors: Bhalchandra Karandikar, Bruce L. Gibbins
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Publication number: 20170258826Abstract: The present invention comprises methods and compositions for delivery devices More particularly, the present invention comprises methods and compositions for devices comprising a matrix comprising a polymer network and a non-gellable polysaccharide having oxygen and optionally active agents incorporated therein. The matrix may be formed into any desired shape for treatment of compromised tissue or for delivery of oxygen to a localized environment.Type: ApplicationFiled: May 25, 2017Publication date: September 14, 2017Inventors: Bruce L. Gibbins, Lance D. Hopman
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Patent number: 9687503Abstract: The present invention comprises methods and compositions for delivery devices More particularly, the present invention comprises methods and compositions for devices comprising a matrix comprising a polymer network and a non-gellable polysaccharide having oxygen and optionally active agents incorporated therein. The matrix may be formed into any desired shape for treatment of compromised tissue or for delivery of oxygen to a localized environment.Type: GrantFiled: January 8, 2014Date of Patent: June 27, 2017Assignee: Avent, Inc.Inventors: Bruce L. Gibbins, Lance D. Hopman
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Patent number: 9289378Abstract: The present invention comprises compositions and methods for providing antimicrobial compositions. The antimicrobial compositions comprise gel delivery vehicles comprising stabilized silver, wherein ionic silver is provided to a site for antimicrobial purposes. Methods of making and using such compositions are taught, including application of the silver-containing gel compositions to wounds, burns, abrasions, cuts, surgical incision, sites where skin or organ integrity has been breached, and other sites to supply an antimicrobial environment.Type: GrantFiled: September 19, 2005Date of Patent: March 22, 2016Assignee: Avent, Inc.Inventors: Bhalchandra M. Karandikar, Bruce L. Gibbins
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Publication number: 20160060458Abstract: An antimicrobial polyurethane foam that is formed from: a multi-functional isocyanate component; an aqueous polyol component reactive with the multi-functional isocyanate component; an antimicrobial metallic compound; and a complexing agent. The complexing agent is used to form a stable blend of the antimicrobial metallic compound with the polyol component. Exemplary complexing agents include amine compounds, ammonium-containing compounds, and ammonia as well as combinations of these compounds. The antimicrobial metallic compound can be a silver, zinc, or copper compound. Desirably, the antimicrobial metallic compound is silver saccharinate. A process of making the antimicrobial polyurethane foam and stable blends used in the manufacture of the antimicrobial polyurethane foam are also disclosed.Type: ApplicationFiled: November 11, 2015Publication date: March 3, 2016Applicant: Avent, Inc.Inventors: Bhalchandra Karandikar, Bruce L. Gibbins
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Publication number: 20160038413Abstract: The present invention comprises compositions and methods for providing antimicrobial compositions. The antimicrobial compositions comprise gel delivery vehicles comprising stabilized silver, wherein ionic silver is provided to a site for antimicrobial purposes. Methods of making and using such compositions are taught, including application of the silver-containing gel compositions to wounds, burns, abrasions, cuts, surgical incision, sites where skin or organ integrity has been breached, and other sites to supply an antimicrobial environment.Type: ApplicationFiled: September 1, 2015Publication date: February 11, 2016Inventors: Bhalchandra M. Karandikar, Bruce L. Gibbins
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Patent number: 9193820Abstract: An antimicrobial polyurethane foam that is formed from: a multi-functional isocyanate component; an aqueous polyol component reactive with the multi-functional isocyanate component; an antimicrobial metallic compound; and a complexing agent. The complexing agent is used to form a stable blend of the antimicrobial metallic compound with the polyol component. Exemplary complexing agents include amine compounds, ammonium-containing compounds, and ammonia as well as combinations of these compounds. The antimicrobial metallic compound can be a silver, zinc, or copper compound. Desirably, the antimicrobial metallic compound is silver saccharinate. A process of making the antimicrobial polyurethane foam and stable blends used in the manufacture of the antimicrobial polyurethane foam are also disclosed.Type: GrantFiled: December 1, 2014Date of Patent: November 24, 2015Assignee: Avent, Inc.Inventors: Bhalchandra M. Karandikar, Bruce L. Gibbins
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Publication number: 20150087739Abstract: An antimicrobial polyurethane foam that is formed from: a multi-functional isocyanate component; an aqueous polyol component reactive with the multi-functional isocyanate component; an antimicrobial metallic compound; and a complexing agent. The complexing agent is used to form a stable blend of the antimicrobial metallic compound with the polyol component. Exemplary complexing agents include amine compounds, ammonium-containing compounds and ammonia as well as combinations these compounds. The antimicrobial metallic compound can be a silver, zinc or copper compound. Desirably, the antimicrobial metallic compound is silver saccharinate. A process of making the antimicrobial polyurethane foam and stable blends used in the manufacture of the antimicrobial polyurethane foam are also disclosed.Type: ApplicationFiled: December 1, 2014Publication date: March 26, 2015Inventors: Bhalchandra M. Karandikar, Bruce L. Gibbins
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Publication number: 20150072066Abstract: The present invention comprises methods and compositions for antimicrobial silver compositions comprising silver nanoparticles. The present invention further comprises compositions for preparing silver nanoparticles comprising at least one stabilizing agent, one or more silver compounds, at least one reducing agent and a solvent. In one aspect, the stabilizing agent comprises a surfactant or a polymer. The polymer may comprise polymers such as polyacrylamides, polyurethanes, and polyamides. In one aspect, the silver compound comprises a salt comprising a silver cation and an anion. The anion may comprise saccharinate derivatives, long chain fatty acids, and alkyl dicarboxylates. The methods of the present invention comprise treating devices with the silver nanoparticle compositions, including, but not limited to, such devices as woven wound care materials, catheters, patient care devices, and collagen matrices.Type: ApplicationFiled: November 18, 2014Publication date: March 12, 2015Inventors: Bhalchandra M. Karandikar, Bruce L. Gibbins, Kenneth A. Cornell
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Patent number: 8900624Abstract: The present invention comprises methods and compositions for antimicrobial silver compositions comprising silver nanoparticles. The present invention further comprises compositions for preparing silver nanoparticles comprising at least one stabilizing agent, one or more silver compounds, at least one reducing agent and a solvent. In one aspect, the stabilizing agent comprises a surfactant or a polymer. The polymer may comprise polymers such as polyacrylamides, polyurethanes, and polyamides. In one aspect, the silver compound comprises a salt comprising a silver cation and an anion. The anion may comprise saccharinate derivatives, long chain fatty acids, and alkyl dicarboxylates. The methods of the present invention comprise treating devices with the silver nanoparticle compositions, including, but not limited to, such devices as woven wound care materials, catheters, patient care devices, and collagen matrices.Type: GrantFiled: August 1, 2005Date of Patent: December 2, 2014Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Bhalchandra M. Karandikar, Bruce L. Gibbins, Ken A. Cornell
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Publication number: 20140120153Abstract: The present invention comprises methods and compositions for delivery devices More particularly, the present invention comprises methods and compositions for devices comprising a matrix comprising a polymer network and a non-gellable polysaccharide having oxygen and optionally active agents incorporated therein. The matrix may be formed into any desired shape for treatment of compromised tissue or for delivery of oxygen to a localized environment.Type: ApplicationFiled: January 8, 2014Publication date: May 1, 2014Applicant: Kimberly-Clark Worldwide, Inc.Inventors: Bruce L. Gibbins, Lance D. Hopman
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Patent number: 8679523Abstract: The present invention comprises methods and compositions for delivery devices. More particularly, the present invention comprises methods and compositions for devices comprising a matrix comprising a polymer network and a non-gellable polysaccharide having oxygen and optionally active agents incorporated therein. The matrix may be formed into any desired shape for treatment of compromised tissue or for delivery of oxygen to a localized environment.Type: GrantFiled: December 29, 2000Date of Patent: March 25, 2014Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Bruce L. Gibbins, Lance D. Hopman
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Publication number: 20130274341Abstract: The present invention comprises methods and compositions for the treatment of pathological conditions of the dermis and dermal structures of animals and humans. In particular, the present invention comprises the use of topical delivery vehicles, including hydrogels, which incorporate active agents such as organic acids, for the treatment of dermal conditions.Type: ApplicationFiled: June 14, 2013Publication date: October 17, 2013Inventors: Joseph C. Maley, Bruce L. Gibbins
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Patent number: 8486426Abstract: The present invention comprises methods and compositions for the treatment of pathological conditions of the dermis and dermal structures of animals and humans. In particular, the present invention comprises the use of topical delivery vehicles, including hydrogels, which incorporate active agents such as organic acids, for the treatment of dermal conditions.Type: GrantFiled: July 29, 2003Date of Patent: July 16, 2013Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Joseph C. Maley, Bruce L. Gibbins
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Patent number: 8361553Abstract: The present invention comprises methods and compositions comprising metal nanoparticles. The invention comprises metal nanoparticles and surfaces treated with a metal nanoparticle coating. The present invention further comprises compositions for preparing nanoparticles comprising at least one stabilizing agent, one or more metal compounds, at least one reducing agent and a solvent. In one aspect, the stabilizing agent comprises a surfactant or a polymer. The polymer may comprise polymers such as polyacrylamides, polyurethanes, and polyamides. In one aspect, the metal compound comprises a salt comprising a metal cation and an anion. The anion may comprise saccharinate derivatives, long chain fatty acids, and alkyl dicarboxylates.Type: GrantFiled: February 8, 2007Date of Patent: January 29, 2013Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Bhalchandra M. Karandikar, Bruce L. Gibbins
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Patent number: 8293965Abstract: The present invention comprises antimicrobial articles for use with a percutaneous device, comprising a matrix which may contact the percutaneous device in a three-dimensional mode and release antimicrobial agents (e.g., silver ions) to the percutaneous device access site. In addition, the antimicrobial article of the present invention may donate moisture to a dry dermal site (e.g., a dry wound bed) and/or absorb liquid or exudates of a dermal site. The present invention also comprises methods for treating and/or preventing an infection using the antimicrobial articles of the present invention.Type: GrantFiled: April 25, 2007Date of Patent: October 23, 2012Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Jack D. McMaken, Bruce L. Gibbins
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Patent number: 8203029Abstract: The present invention comprises methods and compositions for making a silver-containing antimicrobial hydrophilic material. More particularly, the present invention comprises methods and compositions for stabilized silver antimicrobial devices comprising a matrix comprising a polymer network and a non-gellable polysaccharide, and an active agent. The matrix may be formed into any desired shape for its desired uses.Type: GrantFiled: July 28, 2009Date of Patent: June 19, 2012Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Bruce L. Gibbins, Lance D. Hopman
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Publication number: 20100190004Abstract: The present invention comprises methods for making and using antimicrobial laminate constructs comprising an antimicrobial layer and optionally, an adhesive layer. The present invention comprises methods for making medical devices, surfaces that may be in contact with medical equipment, personnel or patients, or treatment areas antimicrobial comprising, for example, applying an antimicrobial laminate construct.Type: ApplicationFiled: November 24, 2009Publication date: July 29, 2010Inventors: Bruce L. Gibbins, Bhalchandra M. Karandikar