Patents by Inventor Bruce M. Held

Bruce M. Held has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7626077
    Abstract: This invention relates to glyphosate-resistant transgenic plants and methods of making the same. In a preferred embodiment, a DNA fragment which comprises an EPSPS 5? regulatory sequence and a glyphosate-resistant EPSPS coding sequence is introduced into regenerable plant cells. The encoded EPSPS has a chloroplast transit peptide. The DNA fragment does not contain a non-EPSPS enhancer. Cells are selected for stable transformation, and the selected cells can be used to regenerate glyphosate-resistant transgenic plants. The DNA fragment used for transformation preferably comprises a modified plant genomic sequence, such as SEQ ID NO: 2, SEQ ID NO:4 or SEQ ID NO: 6. In one embodiment, two DNA fragments of this invention are stably transformed into a plant to confer glyphosate-resistance.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: December 1, 2009
    Assignee: Mertec LLC
    Inventors: Bruce M. Held, Herbert M. Wilson, Philip E. Dykema, Carol J. Lewnau, Janelle C. Eby
  • Patent number: 7045684
    Abstract: This invention relates to glyphosate-resistant transgenic plants and methods of making the same. In a preferred embodiment, a DNA fragment which comprises an EPSPS 5? regulatory sequence and a glyphosate-resistant EPSPS coding sequence is introduced into regenerable plant cells. The encoded EPSPS has a chloroplast transit peptide. The DNA fragment does not contain a non-EPSPS enhancer. Cells are selected for stable transformation, and the selected cells can be used to regenerate glyphosate-resistant transgenic plants. The DNA fragment used for transformation preferably comprises a modified plant genomic sequence, such as SEQ ID NO: 2, SEQ ID NO:4 or SEQ ID NO: 6. In one embodiment, two DNA fragments of this invention are stably transformed into a plant to confer glyphosate-resistance.
    Type: Grant
    Filed: August 19, 2002
    Date of Patent: May 16, 2006
    Assignee: Mertec, LLC
    Inventors: Bruce M. Held, Herbert M. Wilson, Philip E. Dykema, Carol J. Lewnau, Janelle C. Eby
  • Patent number: 5633363
    Abstract: The present invention is directed to promoter fragments isolated from maize and particularly to a 4.7 kbp upstream promoter region designated ZRP2 of a ZRP2 genomic DNA clone, specific fragments thereof designated ZRP2(2.0) and ZRF2(1.0) and functional equivalents thereto. The promoter has particular utility in driving root preferential expression of heterologous genes that impart increased agronomic, horticultural and/or pesticidal characteristics to a given plant. This invention is also directed to DNA molecules including said promoters and transformed plant tissue including a DNA molecule comprising a promoter of the invention operably linked to a heterologous gene or genes and the seeds thereof.
    Type: Grant
    Filed: June 3, 1994
    Date of Patent: May 27, 1997
    Assignee: Iowa State University, Research Foundation In
    Inventors: James T. Colbert, Bruce M. Held, Eve S. Wurtele, Paul S. Dietrich