Patents by Inventor Bruce Markham

Bruce Markham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treating and preventing skeletal muscle deficiencies
    Patent number: 9107940
    Abstract: The present invention relates to compositions and methods for treating and preventing skeletal muscle deficiencies. In particular, the present invention provides compositions comprising poloxamers (e.g., poloxamer 188-P188) and methods of using the same for treating and preventing skeletal muscle deficiencies and injuries (e.g., dystrophin-deficient skeletal muscle; skeletal muscle having a contraction force deficit; skeletal muscle having a Ca2+ imbalance; skeletal muscle having microtears).
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: August 18, 2015
    Assignees: The Regents of the University of Michigan, Phrixus Pharmaceuticals, Inc.
    Inventors: Rainer Ng, Joseph M. Metzger, Lorraine Reeve, Bruce Markham
  • COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING SKELETAL MUSCLE DEFICIENCIES
    Publication number: 20150030559
    Abstract: The present invention relates to compositions and methods for treating and preventing skeletal muscle deficiencies. In particular, the present invention provides compositions comprising poloxamers (e.g., poloxamer 188-P188) and methods of using the same for treating and preventing skeletal muscle deficiencies and injuries (e.g., dystrophin-deficient skeletal muscle; skeletal muscle having a contraction force deficit; skeletal muscle having a Ca2+ imbalance; skeletal muscle having microtears).
    Type: Application
    Filed: October 7, 2014
    Publication date: January 29, 2015
    Inventors: Rainer Ng, Joseph M. Metzger, Lorraine Reeve, Bruce Markham
  • Compositions and methods for treating and preventing skeletal muscle deficiencies
    Patent number: 8852568
    Abstract: The present invention relates to compositions and methods for treating and preventing skeletal muscle deficiencies. In particular, the present invention provides compositions comprising poloxamers (e.g., poloxamer 188-P188) and methods of using the same for treating and preventing skeletal muscle deficiencies and injuries (e.g., dystrophin-deficient skeletal muscle; skeletal muscle having a contraction force deficit; skeletal muscle having a Ca2+ imbalance; skeletal muscle having microtears).
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: October 7, 2014
    Assignees: The Regents of the University of Michigan, Phrixus Pharmaceuticals, Inc.
    Inventors: Rainer Ng, Joseph M. Metzger, Lorraine Reeve, Bruce Markham
  • COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING SKELETAL MUSCLE DEFICIENCIES
    Publication number: 20110033412
    Abstract: The present invention relates to compositions and methods for treating and preventing skeletal muscle deficiencies. In particular, the present invention provides compositions comprising poloxamers (e.g., poloxamer 188-P188) and methods of using the same for treating and preventing skeletal muscle deficiencies and injuries (e.g., dystrophin-deficient skeletal muscle; skeletal muscle having a contraction force deficit; skeletal muscle having a Ca2+ imbalance; skeletal muscle having microtears).
    Type: Application
    Filed: December 17, 2008
    Publication date: February 10, 2011
    Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, PHRIXUS PHARMACEUTICALS, INC.
    Inventors: Rainer Ng, Joseph M. Metzger, Lorraine Reeve, Bruce Markham
  • Sample preparation and slide plating apparatus and method
    Publication number: 20020086431
    Abstract: A method of collecting cells from a specimen and plating such cells onto a slide to create a monolayer. A suspension of cells is filtered to remove unwanted material and monitored to determine if a desired quantity of cells are collected. If insufficient cells are present in the filtered sample, additional suspensions of cells are serially added to the sample and filtered until a desired quantity of cells have been obtained. Devices for collecting samples of cells, for isolating a quantity of cells, and for microscopic examination of a monolayer of cells are also disclosed.
    Type: Application
    Filed: August 16, 2001
    Publication date: July 4, 2002
    Inventors: Walter Bruce Markham, Kenneth Grant Kinsman, Jan Hendrikse, Gordon Robertson