Patents by Inventor Bruce N. Wilkie

Bruce N. Wilkie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for selecting and producing animals having a predicted level of immune response, disease resistance or susceptibility, and/or productivity
    Publication number: 20040235061
    Abstract: The invention relates to methods for selecting animals having a predicted level of immune response, disease resistance or susceptibility, and/or productivity based on an Estimated Breeding Value (EBV) of the animal's immune responsiveness, methods for producing groups of animals having a predicted level of immune response, disease resistance or susceptibility, and/or a predicted productivity based on the EBV; and methods of using such animals.
    Type: Application
    Filed: June 14, 2004
    Publication date: November 25, 2004
    Inventors: Bruce N. Wilkie, Bonnie A Mallard
  • Process for the production of vaccine for prevention of Pasteurella haemolytica pneumonia in bovine
    Patent number: 5378615
    Abstract: A serum-free vaccine effective against pneumonic pasteurellosis in cattle comprising a non-toxic leukotoxin specific for ruminant leukocytes is disclosed. The leukotoxin is prepared in a serum-free medium from a culture of Pasteurella haemolytica. The produced leukotoxin is harvested from the culture medium upon detecting a certain stage during the logarithmic phase of the cell growth to obtain the optimum concentration of produced cytotoxin in the serum-free medium. Cattle may be treated with the vaccine to develop anti-leukotoxic immunity to pneumonic pasterellosis.
    Type: Grant
    Filed: October 9, 1992
    Date of Patent: January 3, 1995
    Assignee: The University of Guelph
    Inventors: Patricia E. Shewen, Bruce N. Wilkie
  • Serum-free, cell-free vaccine effective against pneumonic pasteurellosis in cattle
    Patent number: 5165924
    Abstract: A serum-free vaccine effective against pneumonic pasteurellosis in cattle comprising a non-toxic leukotoxin specific for ruminant leukocytes is disclosed. The leukotoxin is prepared in a serum-free medium from a culture of Pasteurella haemolytica. The produced leukotoxin is harvested from the culture medium upon detecting a certain stage during the logarithmic phase of the cell growth to obtain the optimum concentration of produced cytotoxin in the serum-free medium. Cattle may be treated with the vaccine to develop anti-leukotoxic immunity to pneumonic pasterellosis.
    Type: Grant
    Filed: January 12, 1990
    Date of Patent: November 24, 1992
    Assignee: University of Guelph
    Inventors: Patricia E. Shewen, Bruce N. Wilkie