Abstract: The present invention provides a retractor assembly capable of supporting at least a tissue engaging member in a manner allowing self alignment of the member subject to the pull force of the tissue engaged by the member. The retractor assembly comprises: (i) a frame member which supports a support member; (ii) at least one tissue engaging member which possesses at least a mounting arrangement which is capable of releasably engaging the support member; and (iii) a locking member which is capable of releasably engaging the tissue engaging member with the frame member and the support member to hold the tissue engaging member(s) in a substantially immovable position.

Abstract: A controlled release preparation comprises an ionic polymer matrix loaded with an active compound, particularly a pharmaceutically active compound such as doxorubicin or other cytotoxic or cytostatic drug, the active compound being complexed with a complexing agent such as a metal ion to modify the release of the active compound from the polymer matrix. The ionic polymer matrix may be provided in the form of microspheres, such as microspheres of crosslinked albumin/dextran sulphate.

Abstract: A particulate material which comprises hollow or cup-shaped ceramic microspheres having a diameter in the range of from 5 to 200 microns. The material may comprise a beta- or gamma-emitting radionuclide and be used in selective internal radiation therapy (SIRT) of various forms of cancer and tumours.