Patents by Inventor Bruce Onisko

Bruce Onisko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods to differentiate protein conformers
    Publication number: 20060110785
    Abstract: The invention is directed to methods to distinguish among different protein conformers of the same protein such as proteins which form amyloid deposits. Using the methods of the invention, one or more protein conformers in a sample can be detected, differentiated, and quantitated. An example of a protein which is known to exist in at least two conformations is the normal prion protein (PrPC) and its infectious isoform (PrPSc). The invention provides means to distinguish PrPC from PrPSc and allows quantitation of each individually, even when the conformers are present together in a mixture. Thus, the methods of the invention can provide important tools for human and animal health.
    Type: Application
    Filed: October 13, 2005
    Publication date: May 25, 2006
    Applicants: The U.S.A. as rep. by the Secretary of Agriculture, Universidade De Santiago De Compostela
    Inventors: Bruce Onisko, Christopher Silva, Jesus Requena